Modular pathway engineering of key carbon-precursor supply-pathways for improved N -acetylneuraminic acid production in Bacillus subtilis

In Vivo Multienzyme Complex Coconstruction of N-Acetylneuraminic Acid Lyase and N-Acetylglucosamine-2-epimerase for Biosynthesis of N-Acetylneuraminic Acid

(2017) Zhenfu Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Establishing a synergetic carbon utilization mechanism for non-catabolic use of glucose in microbial synthesis of trehalose

(2017) Yifei Wu et al.   METABOLIC ENGINEERING

Pathway optimization and key enzyme evolution of N -acetylneuraminate biosynthesis using an in vivo aptazyme-based biosensor

(2017) Peng Yang et al.   METABOLIC ENGINEERING

Total Biosynthesis of Legionaminic Acid, a Bacterial Sialic Acid Analogue

(2016) Mohamed I. Hassan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient immobilization of AGE and NAL enzymes onto functional amino resin as recyclable and high-performance biocatalyst

(2016) Jian Cheng et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Examining Escherichia coli glycolytic pathways, catabolite repression, and metabolite channeling using Δpfk mutants

(2016) Whitney D. Hollinshead et al.   Biotechnology for Biofuels

Metabolic engineering of Corynebacterium glutamicum for shikimate overproduction by growth-arrested cell reaction

(2016) Takahisa Kogure et al.   METABOLIC ENGINEERING

NANS-mediated synthesis of sialic acid is required for brain and skeletal development

(2016) Clara D M van Karnebeek et al.   NATURE GENETICS

Characterization of the N-acetylneuraminic acid synthase (NeuB) from the psychrophilic fish pathogen Moritella viscosa

(2015) Tor Olav Berg et al.   CARBOHYDRATE RESEARCH

A synthetic suicide riboswitch for the high-throughput screening of metabolite production in Saccharomyces cerevisiae

(2015) Sang-Woo Lee et al.   METABOLIC ENGINEERING

Rational design of a synthetic Entner–Doudoroff pathway for improved and controllable NADPH regeneration

(2015) Chiam Yu Ng et al.   METABOLIC ENGINEERING

Two-dimensional isobutyl acetate production pathways to improve carbon yield

(2015) Yohei Tashiro et al.   Nature Communications

Molecular characterization of a new N-acetylneuraminate synthase (NeuB1) from Idiomarina loihiensis

(2014) María Inmaculada García García et al.   GLYCOBIOLOGY

Spatial modulation of key pathway enzymes by DNA-guided scaffold system and respiration chain engineering for improved N-acetylglucosamine production by Bacillus subtilis

(2014) Yanfeng Liu et al.   METABOLIC ENGINEERING

Modular pathway engineering of Bacillus subtilis for improved N-acetylglucosamine production

(2014) Yanfeng Liu et al.   METABOLIC ENGINEERING

Engineering of Serine-Deamination pathway, Entner-Doudoroff pathway and pyruvate dehydrogenase complex to improve poly(3-hydroxybutyrate) production in Escherichia coli

(2014) Yan Zhang et al.   Microbial Cell Factories

Retro-biosynthetic screening of a modular pathway design achieves selective route for microbial synthesis of 4-methyl-pentanol

(2014) Micah J. Sheppard et al.   Nature Communications

Microbial production of glucosamine and N-acetylglucosamine: advances and perspectives

(2013) Long Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Pathway engineering of Bacillus subtilis for microbial production of N-acetylglucosamine

(2013) Yanfeng Liu et al.   METABOLIC ENGINEERING

Bacillus subtilis: from soil bacterium to super-secreting cell factory

(2013) Jan Maarten van Dijl et al.   Microbial Cell Factories

Transcriptional regulation is insufficient to explain substrate-induced flux changes in Bacillus subtilis

(2013) V. Chubukov et al.   Molecular Systems Biology

Glycolytic strategy as a tradeoff between energy yield and protein cost

(2013) A. Flamholz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced biofuel production through coupled acetic acid and xylose consumption by engineered yeast

(2013) Na Wei et al.   Nature Communications

Recruiting alternative glucose utilization pathways for improving succinate production

(2012) Jinlei Tang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Engineering of an N-acetylneuraminic acid synthetic pathway in Escherichia coli

(2012) Junhua Kang et al.   METABOLIC ENGINEERING

A Practical Synthesis of Zanamivir Phosphonate Congeners with Potent Anti-influenza Activity

(2011) Jiun-Jie Shie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Simple, fast and high-efficiency transformation system for directed evolution of cellulase in Bacillus subtilis

(2010) Xiao-Zhou Zhang et al.   Microbial Biotechnology

Sialic Acid Is an Essential Nutrient for Brain Development and Cognition

(2009) Bing Wang   Annual Review of Nutrition

Synthetic Approaches to the Neuraminidase Inhibitors Zanamivir (Relenza) and Oseltamivir Phosphate (Tamiflu) for the Treatment of Influenza

(2009) Javier Magano   CHEMICAL REVIEWS

Metabolic Fluxes during Strong Carbon Catabolite Repression by Malate inBacillus subtilis

(2009) Roelco J. Kleijn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cre/lox System and PCR-Based Genome Engineering in Bacillus subtilis

(2008) X. Yan et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY