Bacillus subtilis: from soil bacterium to super-secreting cell factory

Degradation of the Twin-Arginine Translocation Substrate YwbN by Extracytoplasmic Proteases of Bacillus subtilis

(2012) Laxmi Krishnappa et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

High-Salinity Growth Conditions Promote Tat-Independent Secretion of Tat Substrates in Bacillus subtilis

(2012) René van der Ploeg et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

High external pH enables more efficient secretion of alkaline α-amylase AmyK38 by Bacillus subtilis

(2012) Kenji Manabe et al.   Microbial Cell Factories

Comparative transcriptional analysis of Bacillus subtilis cells overproducing either secreted proteins, lipoproteins or membrane proteins

(2012) Bogumiła C Marciniak et al.   Microbial Cell Factories

The LIKE system, a novel protein expression toolbox for Bacillus subtilis based on the liaI promoter

(2012) Anna A Toymentseva et al.   Microbial Cell Factories

Recent advances in engineering the central carbon metabolism of industrially important bacteria

(2012) Maria Papagianni   Microbial Cell Factories

Rational improvement of the engineered isobutanol-producing Bacillus subtilis by elementary mode analysis

(2012) Shanshan Li et al.   Microbial Cell Factories

Membrane Proteases in the Bacterial Protein Secretion and Quality Control Pathway

(2012) R. E. Dalbey et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Structure of the TatC core of the twin-arginine protein transport system

(2012) Sarah E. Rollauer et al.   NATURE

Building the repertoire of dispensable chromosome regions in Bacillus subtilis entails major refinement of cognate large-scale metabolic model

(2012) Kosei Tanaka et al.   NUCLEIC ACIDS RESEARCH

Global Network Reorganization During Dynamic Adaptations of Bacillus subtilis Metabolism

(2012) J. M. Buescher et al.   SCIENCE

Condition-Dependent Transcriptome Reveals High-Level Regulatory Architecture in Bacillus subtilis

(2012) P. Nicolas et al.   SCIENCE

Efficient, Global-Scale Quantification of Absolute Protein Amounts by Integration of Targeted Mass Spectrometry and Two-Dimensional Gel-Based Proteomics

(2011) Sandra Maass et al.   ANALYTICAL CHEMISTRY

Combined Effect of Improved Cell Yield and Increased Specific Productivity Enhances Recombinant Enzyme Production in Genome-Reduced Bacillus subtilis Strain MGB874

(2011) Kenji Manabe et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Functional Implementation of the Posttranslational SecB-SecA Protein-Targeting Pathway in Bacillus subtilis

(2011) Liuyang Diao et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bacterial growth rate reflects a bottleneck in resource allocation

(2011) A. Goelzer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Salt Sensitivity of Minimal Twin Arginine Translocases

(2011) René van der Ploeg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heterologous expression, biochemical characterization, and overproduction of alkaline α-amylase from Bacillus alcalophilus in Bacillus subtilis

(2011) Haiquan Yang et al.   Microbial Cell Factories

Environmental Salinity Determines the Specificity and Need for Tat-Dependent Secretion of the YwbN Protein in Bacillus subtilis

(2011) René van der Ploeg et al.   PLoS One

Post-liberation cleavage of signal peptides is catalyzed by the site-2 protease (S2P) in bacteria

(2011) A. Saito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From the genome sequence to the protein inventory of Bacillus subtilis

(2011) Dörte Becher et al.   PROTEOMICS

Improvement of Sec-dependent secretion of a heterologous model protein in Bacillus subtilis by saturation mutagenesis of the N-domain of the AmyE signal peptide

(2010) Michael Caspers et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Enhanced Extracellular Production of Heterologous Proteins in Bacillus subtilis by Deleting the C-terminal Region of the SecA Secretory Machinery

(2010) Hiroshi Kakeshtia et al.   MOLECULAR BIOTECHNOLOGY

Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis

(2010) Andreas Otto et al.   Nature Communications

Applications of thiol-disulfide oxidoreductases for optimized in vivo production of functionally active proteins in Bacillus

(2009) Thijs R. H. M. Kouwen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Protein transport across and into cell membranes in bacteria and archaea

(2009) Jijun Yuan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later

(2009) V. Barbe et al.   MICROBIOLOGY-SGM

Modulation of Thiol-Disulfide Oxidoreductases for Increased Production of Disulfide-Bond-Containing Proteins in Bacillus subtilis

(2008) T. R. H. M. Kouwen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Reconstruction and analysis of the genetic and metabolic regulatory networks of the central metabolism of Bacillus subtilis

(2008) Anne Goelzer et al.   BMC Systems Biology

Enhanced Recombinant Protein Productivity by Genome Reduction in Bacillus subtilis

(2008) T. Morimoto et al.   DNA RESEARCH

The twin-arginine translocation (Tat) systems from Bacillus subtilis display a conserved mode of complex organization and similar substrate recognition requirements

(2008) James P. Barnett et al.   FEBS Journal

Towards the development of Bacillus subtilis as a cell factory for membrane proteins and protein complexes

(2008) Jessica C Zweers et al.   Microbial Cell Factories

Genetic or chemical protease inhibition causes significant changes in the Bacillus subtilis exoproteome

(2008) Lidia Westers et al.   PROTEOMICS

Ecology and genomics of Bacillus subtilis

(2008) Ashlee M. Earl et al.   TRENDS IN MICROBIOLOGY

Interchangeable modules in bacterial thiol-disulfide exchange pathways

(2008) Thijs R.H.M. Kouwen et al.   TRENDS IN MICROBIOLOGY