Barriers-on-chips: Measurement of barrier function of tissues in organs-on-chips

A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood–brain barrier

(2017) Giulia Adriani et al.   LAB ON A CHIP

WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue

(2017) Peter Loskill et al.   LAB ON A CHIP

Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function

(2017) Olivier Y. F. Henry et al.   LAB ON A CHIP

Wet-AMD on a Chip: Modeling Outer Blood-Retinal Barrier In Vitro

(2017) Minhwan Chung et al.   Advanced Healthcare Materials

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance

(2017) Marinke W. van der Helm et al.   Jove-Journal of Visualized Experiments

Microfluidic co-cultures of retinal pigment epithelial cells and vascular endothelial cells to investigate choroidal angiogenesis

(2017) Li-Jiun Chen et al.   Scientific Reports

Microfluidics for cell-based high throughput screening platforms—A review

(2016) Guansheng Du et al.   ANALYTICA CHIMICA ACTA

Direct quantification of transendothelial electrical resistance in organs-on-chips

(2016) Marinke W. van der Helm et al.   BIOSENSORS & BIOELECTRONICS

Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening

(2016) Ying I. Wang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Geometric correction factor for transepithelial electrical resistance measurements in transwell and microfluidic cell cultures

(2016) J Yeste et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Organization of Endothelial Cells, Pericytes, and Astrocytes into a 3D Microfluidic in Vitro Model of the Blood–Brain Barrier

(2016) Jack D. Wang et al.   MOLECULAR PHARMACEUTICS

Dual flow bioreactor with ultrathin microporous TEER sensing membrane for evaluation of nanoparticle toxicity

(2016) Tommaso Sbrana et al.   SENSORS AND ACTUATORS B-CHEMICAL

A versatile lab-on-a-chip tool for modeling biological barriers

(2016) Fruzsina R. Walter et al.   SENSORS AND ACTUATORS B-CHEMICAL

A microfluidics-based in vitro model of the gastrointestinal human–microbe interface

(2016) Pranjul Shah et al.   Nature Communications

Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip

(2016) Anna Herland et al.   PLoS One

A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors

(2016) Hui Xu et al.   Scientific Reports

Collagen-based brain microvasculature model in vitro using three-dimensional printed template

(2015) Jeong Ah Kim et al.   Biomicrofluidics

Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor

(2015) Jacquelyn A. Brown et al.   Biomicrofluidics

Review: in vitro microvessel models

(2015) Max I. Bogorad et al.   LAB ON A CHIP

Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems

(2015) Mathieu Odijk et al.   LAB ON A CHIP

A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents

(2015) Ilka Maschmeyer et al.   LAB ON A CHIP

Organs-on-chips at the frontiers of drug discovery

(2015) Eric W. Esch et al.   NATURE REVIEWS DRUG DISCOVERY

Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology

(2015) Hansang Cho et al.   Scientific Reports

A Novel Dynamic Neonatal Blood-Brain Barrier on a Chip

(2015) Sudhir P. Deosarkar et al.   PLoS One

Permeability Analysis of Neuroactive Drugs Through a Dynamic Microfluidic In Vitro Blood–Brain Barrier Model

(2014) R. Booth et al.   ANNALS OF BIOMEDICAL ENGINEERING

LiveFaecalibacterium prausnitziiin an apical anaerobic model of the intestinal epithelial barrier

(2014) Dulantha Ulluwishewa et al.   CELLULAR MICROBIOLOGY

Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury

(2014) Mandy B. Esch et al.   LAB ON A CHIP

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Review on Impedance Detection of Cellular Responses in Micro/Nano Environment

(2014) Kin Lei   Micromachines

Materials for Microfluidic Chip Fabrication

(2013) Kangning Ren et al.   ACCOUNTS OF CHEMICAL RESEARCH

Microfluidic heart on a chip for higher throughput pharmacological studies

(2013) Ashutosh Agarwal et al.   LAB ON A CHIP

Capture and 3D culture of colonic crypts and colonoids in a microarray platform

(2013) Yuli Wang et al.   LAB ON A CHIP

In Vitro Perfused Human Capillary Networks

(2013) Monica L. Moya et al.   TISSUE ENGINEERING PART C-METHODS

Micro Total Bioassay System for Oral Drugs: Evaluation of Gastrointestinal Degradation, Intestinal Absorption, Hepatic Metabolism, and Bioactivity

(2012) Yuki IMURA et al.   ANALYTICAL SCIENCES

BBB ON CHIP: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function

(2012) L. M. Griep et al.   BIOMEDICAL MICRODEVICES

Organs-on-chips: breaking the in vitro impasse

(2012) Andries D. van der Meer et al.   Integrative Biology

Artificial lymphatic drainage systems for vascularized microfluidic scaffolds

(2012) Keith H. K. Wong et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Neurological Diseases in Relation to the Blood–Brain Barrier

(2012) Gary A Rosenberg   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Characterization of a microfluidic in vitro model of the blood-brain barrier (μBBB)

(2012) Ross Booth et al.   LAB ON A CHIP

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

SyM-BBB: a microfluidic blood brain barrier model

(2012) Balabhaskar Prabhakarpandian et al.   LAB ON A CHIP

Characterization of drug permeability in Caco-2 monolayers by mass spectrometry on a membrane-based microfluidic device

(2012) Dan Gao et al.   LAB ON A CHIP

NutriChip: nutrition analysis meets microfluidics

(2012) Qasem Ramadan et al.   LAB ON A CHIP

A modular approach to create a neurovascular unit-on-a-chip

(2012) Anil Kumar H. Achyuta et al.   LAB ON A CHIP

In vitro microvessels for the study of angiogenesis and thrombosis

(2012) Y. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Human Disease Model of Drug Toxicity–Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice

(2012) Dongeun Huh et al.   Science Translational Medicine

Microfluidic Transendothelial Electrical Resistance Measurement Device that Enables Blood Flow and Postgrowth Experiments

(2011) Paul A. Vogel et al.   ANALYTICAL CHEMISTRY

The role of shear stress in Blood-Brain Barrier endothelial physiology

(2011) Luca Cucullo et al.   BMC NEUROSCIENCE

Micro Total Bioassay System for Ingested Substances: Assessment of Intestinal Absorption, Hepatic Metabolism, and Bioactivity

(2010) Yuki Imura et al.   ANALYTICAL CHEMISTRY

Fabrication of Two-Layered Channel System with Embedded Electrodes to Measure Resistance Across Epithelial and Endothelial Barriers

(2010) Nicholas J. Douville et al.   ANALYTICAL CHEMISTRY

Permeability of Endothelial and Astrocyte Cocultures: In Vitro Blood–Brain Barrier Models for Drug Delivery Studies

(2010) Guanglei Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Effect of mechanical factors on the function of engineered human blood microvessels in microfluidic collagen gels

(2010) Gavrielle M. Price et al.   BIOMATERIALS

A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells

(2010) Nicholas Ferrell et al.   BIOTECHNOLOGY AND BIOENGINEERING

Blood-Retinal Barrier

(2010) José Cunha-Vaz et al.   EUROPEAN JOURNAL OF OPHTHALMOLOGY

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Parylene-coating in PDMS microfluidic channels prevents the absorption of fluorescent dyes

(2010) Hirotaka Sasaki et al.   SENSORS AND ACTUATORS B-CHEMICAL

Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity

(2009) Gretchen J. Mahler et al.   BIOTECHNOLOGY AND BIOENGINEERING

Integration and application of vitrified collagen in multilayered microfluidic devices for corneal microtissue culture

(2009) Christopher M. Puleo et al.   LAB ON A CHIP