The Sphingosine 1-Phosphate Analogue FTY720 Alleviates Seizure-induced Overexpression of P-Glycoprotein in Rat Hippocampus
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Sphingosine 1-Phosphate Analogue FTY720 Alleviates Seizure-induced Overexpression of P-Glycoprotein in Rat Hippocampus
Authors
Keywords
-
Journal
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Volume 123, Issue 1, Pages 14-20
Publisher
Wiley
Online
2018-01-30
DOI
10.1111/bcpt.12973
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation
- (2017) Veit Rothhammer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction
- (2016) Fuyang Zhang et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Inhibition of p38 mitogen-activated protein kinase signaling reduces multidrug transporter activity and anti-epileptic drug resistance in refractory epileptic rats
- (2016) Yiye Shao et al. JOURNAL OF NEUROCHEMISTRY
- Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus
- (2016) Nicholas H. Varvel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTRup-regulation and astrocyte-mediated inflammation
- (2015) Andrés Miguez et al. HUMAN MOLECULAR GENETICS
- Fingolimod may support neuroprotection via blockade of astrocyte nitric oxide
- (2014) Emanuela Colombo et al. ANNALS OF NEUROLOGY
- FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1
- (2014) Ying Xing et al. Journal of Digestive Diseases
- Prominence of Central Sphingosine-1-Phosphate Receptor-1 in Attenuating Aβ-Induced Injury by Fingolimod
- (2014) Masoumeh Asle-Rousta et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- FTY720 does not protect from traumatic brain injury in mice despite reducing posttraumatic inflammation
- (2014) Stine Mencl et al. JOURNAL OF NEUROIMMUNOLOGY
- Neurorestorative effect of FTY720 in a rat model of Alzheimer's disease: Comparison with Memantine
- (2013) Fatemeh Hemmati et al. BEHAVIOURAL BRAIN RESEARCH
- Effects of Brain IKKβ Gene Silencing by Small Interfering RNA on P-Glycoprotein Expression and Brain Damage in the Rat Kainic Acid-Induced Seizure Model
- (2013) Nian Yu et al. CNS & Neurological Disorders-Drug Targets
- Adjunctive use of verapamil in patients with refractory temporal lobe epilepsy: A pilot study
- (2013) Ali A. Asadi-Pooya et al. EPILEPSY & BEHAVIOR
- P-glycoprotein expression and function in patients with temporal lobe epilepsy: a case-control study
- (2013) Maria Feldmann et al. LANCET NEUROLOGY
- FTY720 Ameliorates Acute Ischemic Stroke in Mice by Reducing Thrombo-Inflammation but Not by Direct Neuroprotection
- (2013) Peter Kraft et al. STROKE
- Neuropathology of the blood–brain barrier and pharmaco-resistance in human epilepsy
- (2012) Joan Y. W. Liu et al. BRAIN
- Sphingosine-1-phosphate inhibits interleukin-1β-induced inflammation in human articular chondrocytes
- (2012) MYUNG-HEE MOON et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Fingolimod (FTY720) inhibits neuroinflammation and attenuates spontaneous convulsions in lithium-pilocarpine induced status epilepticus in rat model
- (2012) Fei Gao et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain
- (2012) R. E. Cannon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis
- (2011) Jeffrey A. Cohen et al. ANNALS OF NEUROLOGY
- A Novel Positron Emission Tomography Imaging Protocol Identifies Seizure-Induced Regional Overactivity of P-Glycoprotein at the Blood-Brain Barrier
- (2011) J. P. Bankstahl et al. JOURNAL OF NEUROSCIENCE
- Nuclear Factor-Kappa B Activity Regulates Brain Expression of P-Glycoprotein in the Kainic Acid-Induced Seizure Rats
- (2011) Nian Yu et al. MEDIATORS OF INFLAMMATION
- Drug-Resistant Epilepsy
- (2011) Patrick Kwan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Celecoxib treatment restores pharmacosensitivity in a rat model of pharmacoresistant epilepsy
- (2010) J Schlichtiger et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mechanisms Underlying Inflammation in Neurodegeneration
- (2010) Christopher K. Glass et al. CELL
- Cyclooxygenase-2 inhibitors prevent trinitrobenzene sulfonic acid-induced P-glycoprotein up-regulation in vitro and in vivo
- (2010) Afraa Zrieki et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Regulation of Multidrug Resistance Protein 1 by Tumor Necrosis Factor in Cultured Glial Cells: Involvement of Nuclear Factor- B and c-Jun N-Terminal Kinase Signaling Pathways
- (2010) P. T. Ronaldson et al. MOLECULAR PHARMACOLOGY
- Regulation of BCRP (ABCG2) and P-Glycoprotein (ABCB1) by Cytokines in a Model of the Human Blood–Brain Barrier
- (2009) Birk Poller et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Targeting Prostaglandin E2 EP1 Receptors Prevents Seizure-Associated P-glycoprotein Up-Regulation
- (2009) A. Pekcec et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition
- (2009) Guido Zibell et al. NEUROPHARMACOLOGY
- COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats
- (2009) Erwin A. van Vliet et al. NEUROPHARMACOLOGY
- Activation of Sphingosine 1-Phosphate Receptor-1 by FTY720 Is Neuroprotective After Ischemic Stroke in Rats
- (2009) Yu Hasegawa et al. STROKE
- Resistance to antiepileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus
- (2008) Jens P. Bankstahl et al. EPILEPSY RESEARCH
- Central nervous system-directed effects of FTY720 (fingolimod)
- (2008) Veronique E. Miron et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Glutamate is critically involved in seizure-induced overexpression of P-glycoprotein in the brain
- (2008) Jens P. Bankstahl et al. NEUROPHARMACOLOGY
- Seizure-Induced Up-Regulation of P-Glycoprotein at the Blood-Brain Barrier through Glutamate and Cyclooxygenase-2 Signaling
- (2007) B. Bauer et al. MOLECULAR PHARMACOLOGY
- Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy
- (2007) Teresa Ravizza et al. NEUROBIOLOGY OF DISEASE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started