Inhibition of p38 mitogen-activated protein kinase signaling reduces multidrug transporter activity and anti-epileptic drug resistance in refractory epileptic rats

Exogenous Hydrogen Sulfide Protects against Doxorubicin-Induced Inflammation and Cytotoxicity by Inhibiting p38MAPK/NFκB Pathway in H9c2 Cardiac Cells

(2017) Runmin Guo et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Crotoxin induces apoptosis and autophagy in human lung carcinoma cells in vitro via activation of the p38MAPK signaling pathway

(2014) Rong Han et al.   ACTA PHARMACOLOGICA SINICA

Zuo Jin Wan reverses P-gp-mediated drug-resistance by inhibiting activation of the PI3K/Akt/NF-κB pathway

(2014) Hua Sui et al.   BMC Complementary and Alternative Medicine

A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury

(2014) Muhammad Ashraf et al.   Cell Communication and Signaling

Down-regulation of the P-glycoprotein relevant for multidrug resistance by intracellular acidification through the crosstalk of MAPK signaling pathways

(2014) Weina Jin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Beneficial effect of tetrandrine on refractory epilepsy via suppressing P-glycoprotein

(2014) Yinghui Chen et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

The Cross-Talk between Canonical and Non-Canonical Wnt-Dependent Pathways Regulates P-Glycoprotein Expression in Human Blood–Brain Barrier Cells

(2014) Martha L Pinzón-Daza et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The multidrug transporter P-glycoprotein in pharmacoresistance to antiepileptic drugs

(2014) Karolina M. Stępień et al.   Pharmacological Reports

The Inhibitory Effect of Pseudolaric Acid B on Gastric Cancer and Multidrug Resistance via Cox-2/PKC-α/P-gp Pathway

(2014) Qian Sun et al.   PLoS One

Downregulation ofMDR1Gene by Cepharanthine Hydrochloride Is Related to the Activation of c-Jun/JNK in K562/ADR Cells

(2014) Li Han et al.   Biomed Research International

Multidrug resistance-associated protein 1 decreases the concentrations of antiepileptic drugs in cortical extracellular fluid in amygdale kindling rats

(2013) Ying-hui Chen et al.   ACTA PHARMACOLOGICA SINICA

P-glycoprotein expression and function in patients with temporal lobe epilepsy: a case-control study

(2013) Maria Feldmann et al.   LANCET NEUROLOGY

Inhibition of p38 MAPK diminishes doxorubicin-induced drug resistance associated with P-glycoprotein in human leukemia K562 cells

(2013) Yinghui Chen et al.   MEDICAL SCIENCE MONITOR

The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer's disease

(2013) Ayman ElAli et al.   Frontiers in Physiology

Dual regulation of P-glycoprotein expression by Trichostatin A in cancer cell lines

(2012) Trinidad Balaguer et al.   BMC MOLECULAR BIOLOGY

Heat shock factor-1 knockout induces multidrug resistance gene, MDR1b, and enhances P-glycoprotein (ABCB1)-based drug extrusion in the heart

(2012) K. Krishnamurthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Up-regulation of P-glycoprotein is involved in the increased paclitaxel resistance in human esophageal cancer radioresistant cells

(2012) Yan Wang et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

The Abluminal Endothelial Membrane in Neurovascular Remodeling in Health and Disease

(2012) D. M. Hermann et al.   Science Signaling

Cerebral expression of drug transporters in epilepsy

(2011) Eleonora Aronica et al.   ADVANCED DRUG DELIVERY REVIEWS

ATP-Binding Cassette Transporters and Their Roles in Protecting the Brain

(2011) Ayman ElAli et al.   NEUROSCIENTIST

Association between temporal lobe P-glycoprotein expression and seizure recurrence after surgery for pharmacoresistant temporal lobe epilepsy

(2010) Patrick Kwan et al.   NEUROBIOLOGY OF DISEASE

Xenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral Function

(2009) F. Dutheil et al.   DRUG METABOLISM AND DISPOSITION

COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats

(2009) Erwin A. van Vliet et al.   NEUROPHARMACOLOGY

p38MAPK inhibition attenuates LPS-induced acute lung injury involvement of NF-κB pathway

(2008) Su Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Acidosis induces multi-drug resistance in rat prostate cancer cells (AT1)in vitroandin vivoby increasing the activity of the p-glycoproteinviaactivation of p38

(2008) Christoph Sauvant et al.   INTERNATIONAL JOURNAL OF CANCER

CDKL5 mutations in boys with severe encephalopathy and early-onset intractable epilepsy

(2008) M. Elia et al.   NEUROLOGY