FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1

ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development

(2014) Young Choi et al.   CURRENT PHARMACEUTICAL DESIGN

PD173074, a selective FGFR inhibitor, reverses ABCB1-mediated drug resistance in cancer cells

(2013) Atish Patel et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Vitamin E reverses multidrug resistance in vitro and in vivo

(2013) Jingling Tang et al.   CANCER LETTERS

Regulation of LC3-Dependent Protective Autophagy in Ovarian Cancer Cells by Protein Phosphatase 2A

(2013) Xia Yin et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Signal Transduction Pathways and Transcriptional Mechanisms of ABCB1/Pgp-mediated Multiple Drug Resistance in Human Cancer Cells

(2013) H Sui et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

FTY720 inhibits tumor growth and enhances the tumor-suppressive effect of topotecan in neuroblastoma by interfering with the sphingolipid signaling pathway

(2013) Mei-Hong Li et al.   PEDIATRIC BLOOD & CANCER

BBA, a Synthetic Derivative of 23-hydroxybutulinic Acid, Reverses Multidrug Resistance by Inhibiting the Efflux Activity of MRP7 (ABCC10)

(2013) Jun-Jiang Chen et al.   PLoS One

Erlotinib antagonizes ABC transporters in acute myeloid leukemia

(2012) Elodie Lainey et al.   CELL CYCLE

Autophagy induced by FTY720 promotes apoptosis in U266 cells

(2012) Aijun Liao et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Effects of 3β-Acethyl Tormentic Acid (3ATA) on ABCC Proteins Activity

(2012) Gleice da Graça Rocha et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A randomized, controlled trial of fingolimod (FTY720) in Japanese patients with multiple sclerosis

(2012) T Saida et al.   Multiple Sclerosis Journal

Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma

(2012) A. Estrada-Bernal et al.   NEURO-ONCOLOGY

Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain

(2012) R. E. Cannon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death

(2011) L. Alinari et al.   BLOOD

Indomethacin and SC236 enhance the cytotoxicity of doxorubicin in human hepatocellular carcinoma cells via inhibiting P-glycoprotein and MRP1 expression

(2011) Cai-Guo Ye et al.   CANCER LETTERS

Fingolimod in multiple sclerosis: Mechanisms of action and clinical efficacy

(2011) Jens Ingwersen et al.   CLINICAL IMMUNOLOGY

Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases

(2011) Zhe-Sheng Chen et al.   FEBS Journal

Reversal of multidrug resistance in human breast cancer cells by Curcuma wenyujin and Chrysanthemum indicum

(2011) L. Yang et al.   PHYTOMEDICINE

Sensitive and Specific Fluorescent Probes for Functional Analysis of the Three Major Types of Mammalian ABC Transporters

(2011) Irina V. Lebedeva et al.   PLoS One

FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy

(2010) Ning Zhang et al.   Autophagy

FTY720 (Fingolimod) Sensitizes Prostate Cancer Cells to Radiotherapy by Inhibition of Sphingosine Kinase-1

(2010) D. Pchejetski et al.   CANCER RESEARCH

PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice

(2010) Tongsen Zheng et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Ceramide Synthesis Is Modulated by the Sphingosine Analog FTY720 via a Mixture of Uncompetitive and Noncompetitive Inhibition in an Acyl-CoA Chain Length-de pend ent Manner

(2009) Sujoy Lahiri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FTY720 Inhibits Ceramide Synthases and Up-regulates Dihydrosphingosine 1-Phosphate Formation in Human Lung Endothelial Cells

(2009) Evgeny V. Berdyshev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ganglioside composition of differentiated Caco-2 cells resembles human colostrum and neonatal rat intestine

(2008) Kareena L. Schnabl et al.   BRITISH JOURNAL OF NUTRITION

FTY720 Induces Apoptosis in Hepatocellular Carcinoma Cells through Activation of Protein Kinase C   Signaling

(2008) J.-H. Hung et al.   CANCER RESEARCH