Identification of autophagy as a longevity-assurance mechanism in the aging modelPodospora anserina

Modulation of the glyoxalase system in the aging model Podospora anserina: effects on growth and lifespan

(2016) Christian Q. Scheckhuber et al.   Aging-US

PaCATB, a secreted catalase protecting Podospora anserina against exogenous oxidative stress

(2016) Sandra Zintel et al.   Aging-US

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

(2014) Anne Simonsen et al.   Autophagy

The effects of p53 on whole organism longevity are mediated by autophagy

(2014) Nektarios Tavernarakis et al.   Autophagy

Longevity pathways converge on autophagy genes to regulate life span inCaenorhabditis elegans

(2014) Márton L. Tóth et al.   Autophagy

A novel link between autophagy and the ubiquitin-proteasome system

(2014) Viktor I. Korolchuk et al.   Autophagy

Autophagy is required for extension of yeast chronological life span by rapamycin

(2014) Ashley L. Alvers et al.   Autophagy

Live-cell imaging ofAspergillus nidulansautophagy

(2013) Mario Pinar et al.   Autophagy

Structural basis for phosphorylation-triggered autophagic clearance ofSalmonella

(2013) Vladimir V. Rogov et al.   BIOCHEMICAL JOURNAL

Quality control of mitochondria during aging: Is there a good and a bad side of mitochondrial dynamics?

(2013) Marc Thilo Figge et al.   BIOESSAYS

Selective Autophagy: Talking with the UPS

(2013) Caroline Park et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast

(2013) John P. Aris et al.   EXPERIMENTAL GERONTOLOGY

Mitochondrial Quality Control: Impact on Aging and Life Span - A Mini-Review

(2013) Heinz D. Osiewacz et al.   GERONTOLOGY

Autophagic kinases SmVPS34 and SmVPS15 are required for viability in the filamentous ascomycete Sordaria macrospora

(2013) Oliver Voigt et al.   MICROBIOLOGICAL RESEARCH

A Genome-Wide Longitudinal Transcriptome Analysis of the Aging Model Podospora anserine

(2013) Oliver Philipp et al.   PLoS One

Human CLPP reverts the longevity phenotype of a fungal ClpP deletion strain

(2013) Fabian Fischer et al.   Nature Communications

Autophagy genesSmatg8andSmatg4are required for fruiting-body development, vegetative growth and ascospore germination in the filamentous ascomyceteSordaria macrospora

(2012) Oliver Voigt et al.   Autophagy

Mitochondrial quality control in aging and lifespan control of the fungal aging modelPodospora anserina: Figure 1

(2012) Heinz D. Osiewacz   BIOCHEMICAL SOCIETY TRANSACTIONS

Unmasking a temperature-dependent effect of theP. anserinai-AAA protease on aging and development

(2012) Andrea Weil et al.   CELL CYCLE

Loss of autophagy in hypothalamic POMC neurons impairs lipolysis

(2012) Susmita Kaushik et al.   EMBO REPORTS

Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans

(2012) Alfonso Schiavi et al.   EXPERIMENTAL GERONTOLOGY

Biological Roles of the Podospora anserina Mitochondrial Lon Protease and the Importance of Its N-Domain

(2012) Céline Adam et al.   PLoS One

Angiogenesis Impairment in Diabetes: Role of Methylglyoxal-Induced Receptor for Advanced Glycation Endproducts, Autophagy and Vascular Endothelial Growth Factor Receptor 2

(2012) Hongtao Liu et al.   PLoS One

Mitochondrial quality control: an integrated network of pathways

(2012) Fabian Fischer et al.   TRENDS IN BIOCHEMICAL SCIENCES

Deceleration of Fusion–Fission Cycles Improves Mitochondrial Quality Control during Aging

(2012) Marc Thilo Figge et al.   PLoS Computational Biology

Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

(2011) Mingzhan Xue et al.   BIOCHEMICAL JOURNAL

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans

(2010) Wen Yang et al.   AGING CELL

Cyclophilin D links programmed cell death and organismal aging in Podospora anserina

(2010) Diana Brust et al.   AGING CELL

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

(2010) Ivana Bjedov et al.   Cell Metabolism

Deletion of PaAif2 and PaAmid2, two genes encoding mitochondrial AIF-like oxidoreductases of Podospora anserina, leads to increased stress tolerance and lifespan extension

(2010) Diana Brust et al.   CURRENT GENETICS

Increasing mitochondrial superoxide dismutase abundance leads to impairments in protein quality control and ROS scavenging systems and to lifespan shortening

(2010) Sandra Zintel et al.   EXPERIMENTAL GERONTOLOGY

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

Fast, high-contrast imaging of animal development with scanned light sheet–based structured-illumination microscopy

(2010) Philipp J Keller et al.   NATURE METHODS

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

(2010) M. M. Lipinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monitoring mitophagy in yeast: The Om45-GFP processing assay

(2009) Tomotake Kanki et al.   Autophagy

TOR-dependent control of autophagy: biting the hand that feeds

(2009) Thomas P Neufeld   CURRENT OPINION IN CELL BIOLOGY

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

(2009) Martin Gamerdinger et al.   EMBO JOURNAL

Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems

(2009) Viktor I. Korolchuk et al.   FEBS LETTERS

SmATG7 is required for viability in the homothallic ascomycete Sordaria macrospora

(2009) Nicole Nolting et al.   FUNGAL GENETICS AND BIOLOGY

Effect of rapamycin on lifespan inDrosophila

(2009) Benjamin Harrison et al.   Geriatrics & Gerontology International

A potential impact of DNA repair on ageing and lifespan in the ageing model organism Podospora anserina: Decrease in mitochondrial DNA repair activity during ageing

(2009) Mette Soerensen et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Increasing organismal healthspan by enhancing mitochondrial protein quality control

(2009) Karin Luce et al.   NATURE CELL BIOLOGY

Over-expression of an S-adenosylmethionine-dependent methyltransferase leads to an extended lifespan ofPodospora anserinawithout impairments in vital functions

(2008) Birgit Kunstmann et al.   AGING CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Autophagy genes and ageing

(2008) T Vellai   CELL DEATH AND DIFFERENTIATION

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Autophagy in filamentous fungi

(2008) J POLLACK et al.   FUNGAL GENETICS AND BIOLOGY

Mitophagy in Yeast Occurs through a Selective Mechanism

(2008) Tomotake Kanki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

(2008) Claudine Kraft et al.   NATURE CELL BIOLOGY

Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement

(2008) Tianhong Pan et al.   NEUROBIOLOGY OF DISEASE

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

(2008) Malene Hansen et al.   PLoS Genetics

Apoptosis pathways in fungal growth, development and ageing

(2008) Andrea Hamann et al.   TRENDS IN MICROBIOLOGY