Mapping the SUMOylated landscape

SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites

(2015) R. Gonzalez-Prieto et al.   EMBO REPORTS

System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability

(2015) Zhenyu Xiao et al.   MOLECULAR & CELLULAR PROTEOMICS

The SLX4 Complex Is a SUMO E3 Ligase that Impacts on Replication Stress Outcome and Genome Stability

(2015) Jean-Hugues Guervilly et al.   MOLECULAR CELL

Noncovalent Interactions with SUMO and Ubiquitin Orchestrate Distinct Functions of the SLX4 Complex in Genome Maintenance

(2015) Jian Ouyang et al.   MOLECULAR CELL

SUMO-mediated regulation of DNA damage repair and responses

(2015) Prabha Sarangi et al.   TRENDS IN BIOCHEMICAL SCIENCES

System-wide identification of wild-type SUMO-2 conjugation sites

(2015) Ivo A. Hendriks et al.   Nature Communications

SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage

(2015) Ivo A. Hendriks et al.   Cell Reports

SUMO2 is essential while SUMO3 is dispensable for mouse embryonic development

(2014) L. Wang et al.   EMBO REPORTS

Oxidative stress–induced assembly of PML nuclear bodies controls sumoylation of partner proteins

(2014) Umut Sahin et al.   JOURNAL OF CELL BIOLOGY

Uncovering SUMOylation Dynamics during Cell-Cycle Progression Reveals FoxM1 as a Key Mitotic SUMO Target Protein

(2014) Joost Schimmel et al.   MOLECULAR CELL

Uncovering global SUMOylation signaling networks in a site-specific manner

(2014) Ivo A Hendriks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

GPS-SUMO: a tool for the prediction of sumoylation sites and SUMO-interaction motifs

(2014) Qi Zhao et al.   NUCLEIC ACIDS RESEARCH

Proteome-Wide Identification of SUMO2 Modification Sites

(2014) T. Tammsalu et al.   Science Signaling

PML nuclear bodies: Assembly and oxidative stress-sensitive sumoylation

(2014) Umut Sahin et al.   Nucleus

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

Control of Nuclear Activities by Substrate-Selective and Protein-Group SUMOylation

(2013) Stefan Jentsch et al.   Annual Review of Genetics

SUMO-targeted ubiquitin ligases

(2013) Annie M. Sriramachandran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

SUMO: A Multifaceted Modifier of Chromatin Structure and Function

(2013) Caelin Cubeñas-Potts et al.   DEVELOPMENTAL CELL

Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response

(2013) Yung-Lin Hsieh et al.   EMBO JOURNAL

RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

(2013) Sara L. Poulsen et al.   JOURNAL OF CELL BIOLOGY

Targeted Identification of SUMOylation Sites in Human Proteins Using Affinity Enrichment and Paralog-specific Reporter Ions

(2013) Frederic Lamoliatte et al.   MOLECULAR & CELLULAR PROTEOMICS

Arkadia, a Novel SUMO-Targeted Ubiquitin Ligase Involved in PML Degradation

(2013) Y. Erker et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of DNA Damage Responses by Ubiquitin and SUMO

(2013) Stephen P. Jackson et al.   MOLECULAR CELL

Detecting endogenous SUMO targets in mammalian cells and tissues

(2013) Janina Becker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SUMO Rules: Regulatory Concepts and Their Implication in Neurologic Functions

(2013) Mathias Droescher et al.   NEUROMOLECULAR MEDICINE

Senp1 Is Essential for Desumoylating Sumo1-Modified Proteins but Dispensable for Sumo2 and Sumo3 Deconjugation in the Mouse Embryo

(2013) Prashant Sharma et al.   Cell Reports

Protein Group Modification and Synergy in the SUMO Pathway as Exemplified in DNA Repair

(2012) Ivan Psakhye et al.   CELL

SUMOylation in Control of Accurate Chromosome Segregation during Mitosis

(2012) Jun Wan et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions

(2012) Sarah Schulz et al.   EMBO REPORTS

Identification of protein SUMOylation sites by mass spectrometry using combined microwave-assisted aspartic acid cleavage and tryptic digestion

(2012) Omoruyi Osula et al.   JOURNAL OF MASS SPECTROMETRY

The RanBP2/RanGAP1∗SUMO1/Ubc9 Complex Is a Multisubunit SUMO E3 Ligase

(2012) Andreas Werner et al.   MOLECULAR CELL

Function and regulation of SUMO proteases

(2012) Christopher M. Hickey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phosphorylation of Ubc9 by Cdk1 Enhances SUMOylation Activity

(2012) Yee-Fun Su et al.   PLoS One

In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice

(2012) M. Tirard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uncovering Ubiquitin and Ubiquitin-like Signaling Networks

(2011) Alfred C. O. Vertegaal   CHEMICAL REVIEWS

Purification and identification of endogenous polySUMO conjugates

(2011) Roland Bruderer et al.   EMBO REPORTS

The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

(2011) Simon Bekker-Jensen et al.   FEBS LETTERS

Analysis of Oxygen/Glucose-Deprivation-Induced Changes in SUMO3 Conjugation Using SILAC-Based Quantitative Proteomics

(2011) Wei Yang et al.   JOURNAL OF PROTEOME RESEARCH

SUMO1-dependent modulation of SERCA2a in heart failure

(2011) Changwon Kho et al.   NATURE

SUMO chains: polymeric signals: Figure 1

(2010) Alfred C.O. Vertegaal   BIOCHEMICAL SOCIETY TRANSACTIONS

Site-Specific Identification of SUMO-2 Targets in Cells Reveals an Inverted SUMOylation Motif and a Hydrophobic Cluster SUMOylation Motif

(2010) Ivan Matic et al.   MOLECULAR CELL

PHOSIDA 2011: the posttranslational modification database

(2010) F. Gnad et al.   NUCLEIC ACIDS RESEARCH

Proteomic analyses identify a diverse array of nuclear processes affected by small ubiquitin-like modifier conjugation in Arabidopsis

(2010) M. J. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

System-Wide Changes to SUMO Modifications in Response to Heat Shock

(2009) F. Golebiowski et al.   Science Signaling

Activity profiling of human deSUMOylating enzymes (SENPs) with synthetic substrates suggests an unexpected specificity of two newly characterized members of the family

(2008) Marcin Drag et al.   BIOCHEMICAL JOURNAL

Resolution of Sister Centromeres Requires RanBP2-Mediated SUMOylation of Topoisomerase IIα

(2008) Meelad M. Dawlaty et al.   CELL

Structure of the Human SENP7 Catalytic Domain and Poly-SUMO Deconjugation Activities for SENP6 and SENP7

(2008) Christopher D. Lima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3

(2008) E. Evdokimov et al.   JOURNAL OF CELL SCIENCE

Ubc9 Sumoylation Regulates SUMO Target Discrimination

(2008) Puck Knipscheer et al.   MOLECULAR CELL

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

Emerging roles of the SUMO pathway in mitosis

(2008) Mary Dasso   Cell Division