Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126

A path analysis of multiple neurotoxic chemicals and cognitive functioning in older US adults (NHANES 1999–2002)

(2017) Jennifer Przybyla et al.   Environmental Health

Pesticides, polychlorinated biphenyls and polycyclic aromatic hydrocarbons in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a case-control study

(2017) Marco Vinceti et al.   ENVIRONMENTAL RESEARCH

Tailored liquid chromatography–mass spectrometry analysis improves the coverage of the intracellular metabolome of HepaRG cells

(2017) Matthias Cuykx et al.   JOURNAL OF CHROMATOGRAPHY A

Endocrine-disrupting chemicals and fatty liver disease

(2017) Charles E. Foulds et al.   Nature Reviews Endocrinology

Metabolism disrupting chemicals and metabolic disorders

(2017) Jerrold J. Heindel et al.   REPRODUCTIVE TOXICOLOGY

Editor’s Highlight: Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis

(2017) Michelle M. Angrish et al.   TOXICOLOGICAL SCIENCES

Editor’s Highlight: Transcriptome Profiling Reveals Bisphenol A Alternatives Activate Estrogen Receptor Alpha in Human Breast Cancer Cells

(2017) Robin Mesnage et al.   TOXICOLOGICAL SCIENCES

Endocrine Disruptors Leading to Obesity and Related Diseases

(2017) Demetrios Petrakis et al.   International Journal of Environmental Research and Public Health

Obesogens: an emerging threat to public health

(2016) Amanda S. Janesick et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Computational methods to identify metabolic sub-networks based on metabolomic profiles

(2016) Clément Frainay et al.   BRIEFINGS IN BIOINFORMATICS

Sex-Dependent Effects of Cadmium Exposure in Early Life on Gut Microbiota and Fat Accumulation in Mice

(2016) Qian Ba et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The economic and clinical burden of nonalcoholic fatty liver disease in the United States and Europe

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Simulating real-life exposures to uncover possible risks to human health: A proposed consensus for a novel methodological approach

(2016) AM Tsatsakis et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown

(2016) Mihaela Pertea et al.   Nature Protocols

Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd

(2016) Zichen Wang et al.   Nature Communications

Environmental Contaminants and Pancreatic Beta-Cells

(2016) Gabriel Fabricio et al.   Journal of Clinical Research in Pediatric Endocrinology

Silica-Triggered Autoimmunity in Lupus-Prone Mice Blocked by Docosahexaenoic Acid Consumption

(2016) Melissa A. Bates et al.   PLoS One

Metabolism and metabolites of polychlorinated biphenyls

(2015) Fabian A. Grimm et al.   CRITICAL REVIEWS IN TOXICOLOGY

Dioxin-like PCB levels in maternal and umbilical cord sera of people living near dump sites in southern Italy: a pilot study of biomonitoring

(2015) Lucia Grumetto et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Pure non-dioxin-like PCB congeners suppress induction of AhR-dependent endpoints in rat liver cells

(2015) Petra Brenerová et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Altered hepatic gene expression in nonalcoholic fatty liver disease is associated with lower hepatic n-3 and n-6 polyunsaturated fatty acids

(2015) Bianca M. Arendt et al.   HEPATOLOGY

Ballgown bridges the gap between transcriptome assembly and expression analysis

(2015) Alyssa C Frazee et al.   NATURE BIOTECHNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Functional Analysis of the Dioxin Response Elements (DREs) of the Murine CYP1A1 Gene Promoter: Beyond the Core DRE Sequence

(2014) Shuaizhang Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Environmental Influences on Systemic Lupus Erythematosus Expression

(2014) Diane L. Kamen   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Identification of Environmental Chemicals Associated with the Development of Toxicant-associated Fatty Liver Disease in Rodents

(2014) Laila Al-Eryani et al.   TOXICOLOGIC PATHOLOGY

Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease

(2014) Banrida Wahlang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Association between prenatal polychlorinated biphenyl exposure and obesity development at ages 5 and 7 y: a prospective cohort study of 656 children from the Faroe Islands

(2013) Jeanett L Tang-Péronard et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

A community-driven global reconstruction of human metabolism

(2013) Ines Thiele et al.   NATURE BIOTECHNOLOGY

NAFLD, NASH and liver cancer

(2013) Gregory A. Michelotti et al.   Nature Reviews Gastroenterology & Hepatology

Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines

(2013) Sabine U. Vorrink et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

3D organotypic HepaRG cultures as in vitro model for acute and repeated dose toxicity studies

(2013) Daniel Mueller et al.   TOXICOLOGY IN VITRO

Putative Mechanisms of Environmental Chemical–Induced Steatosis

(2012) J. Phillip Kaiser et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Toxicant-associated Steatohepatitis

(2012) Banrida Wahlang et al.   TOXICOLOGIC PATHOLOGY

Toxic effects of pesticide mixtures at a molecular level: Their relevance to human health

(2012) Antonio F. Hernández et al.   TOXICOLOGY

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Differential gene expression and a functional analysis of PCB-exposed children: Understanding disease and disorder development

(2011) Sisir K. Dutta et al.   ENVIRONMENT INTERNATIONAL

Polychlorinated Biphenyls, Lead, and Mercury Are Associated with Liver Disease in American Adults: NHANES 2003–2004

(2010) Matt Cave et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

MetExplore: a web server to link metabolomic experiments and genome-scale metabolic networks

(2010) L. Cottret et al.   NUCLEIC ACIDS RESEARCH

Gene ontology analysis for RNA-seq: accounting for selection bias

(2010) Matthew D Young et al.   GENOME BIOLOGY

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Filtering for increased power for microarray data analysis

(2009) Amber J Hackstadt et al.   BMC BIOINFORMATICS

Toxicant-associated steatohepatitis in vinyl chloride workers

(2009) Matt Cave et al.   HEPATOLOGY

Toxicology for the twenty-first century

(2009) Thomas Hartung   NATURE

Anti‐histones antibodies in systemic lupus erythematosus: prevalence and frequency in neuropsychiatric lupus

(2008) Xiao‐Yun Sun et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

A Sparse PLS for Variable Selection when Integrating Omics Data

(2008) Kim-Anh Lê Cao et al.   Statistical Applications in Genetics and Molecular Biology