Editor’s Highlight: Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis

Quantitative Adverse Outcome Pathways and Their Application to Predictive Toxicology

(2017) Rory B. Conolly et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

High-Throughput Screening of Chemical Effects on Steroidogenesis Using H295R Human Adrenocortical Carcinoma Cells

(2016) Agnes L. Karmaus et al.   TOXICOLOGICAL SCIENCES

Tipping the Balance: Hepatotoxicity and the 4 Apical Key Events of Hepatic Steatosis

(2016) Michelle M. Angrish et al.   TOXICOLOGICAL SCIENCES

Advantageous use of HepaRG cells for the screening and mechanistic study of drug-induced steatosis

(2016) Laia Tolosa et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Integrated Model of Chemical Perturbations of a Biological Pathway Using 18In VitroHigh-Throughput Screening Assays for the Estrogen Receptor

(2015) Richard S. Judson et al.   TOXICOLOGICAL SCIENCES

Adverse Outcome Pathway (AOP) Development I: Strategies and Principles

(2014) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Incorporating New Technologies Into Toxicity Testing and Risk Assessment: Moving From 21st Century Vision to a Data-Driven Framework

(2013) Russell S. Thomas et al.   TOXICOLOGICAL SCIENCES

Putative Mechanisms of Environmental Chemical–Induced Steatosis

(2012) J. Phillip Kaiser et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in heparg cells

(2011) Sébastien Anthérieu et al.   HEPATOLOGY

Peroxisome proliferator-activated receptor-α agonist, Wy 14 643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis

(2011) Claire Z Larter et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The liver X receptor modulator 22(S)-hydroxycholesterol exerts cell-type specific effects on lipid and glucose metabolism

(2011) Nina Pettersen Hessvik et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells

(2010) Anke Van Summeren et al.   TOXICOLOGICAL SCIENCES

Cytochrome P450 and Steatosis

(2009) Maria Gomez-Lechon et al.   CURRENT DRUG METABOLISM

Conceptualizing the healthscape: Contributions of time geography, location technologies and spatial ecology to place and health research

(2009) Daniel Rainham et al.   SOCIAL SCIENCE & MEDICINE

Evaluation of HepaRG Cells as an in Vitro Model for Human Drug Metabolism Studies

(2008) K. P. Kanebratt et al.   DRUG METABOLISM AND DISPOSITION

Thematic Review Series: Glycerolipids.DGAT enzymes and triacylglycerol biosynthesis

(2008) Chi-Liang Eric Yen et al.   JOURNAL OF LIPID RESEARCH