4.4 Article

Phylogenetic diversity and metabolic potential of microbiome of natural healing clay from Chamliyal (J&K)

Journal

ARCHIVES OF MICROBIOLOGY
Volume 200, Issue 9, Pages 1333-1343

Publisher

SPRINGER
DOI: 10.1007/s00203-018-1549-4

Keywords

Clay; Minerals; Microbes; Metagenomics; Phylogeny; Functional diversity

Categories

Funding

  1. Department of Science and Technology (DST), Govt. of India
  2. Council of Scientific and Industrial Research (CSIR), Government of India [38(1269)/10/EMR-II]
  3. Department of Biotechnology (DBT), Government of India

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Clay therapy for skin disease treatment is an ancient practice popular worldwide as a cheap alternative to pharmaceutical products. Effectiveness of clay against skin problems has been linked to its mineral composition and to microbial activity. The clay-water paste of a holy shrine Chamliyal in the Jammu region of J&K, India is used as an ointment to treat different skin disorders particularly psoriasis. Using the 16 SrDNA amplicon pyrosequencing and whole-metagenome direct shotgun Illumina sequencing, microbial phylogeny and potential metabolic functions were catalogued for Chamliyal's clay. Microbial diversity profile of the Chamliyal's clay is similar to other medicinal clays, particularly Dead Sea; there is some uniqueness as well. Although Proteobacteria, Actinomycetes and Firmicutes are common inhabitants of all the clay types, sulphur- and iron-reducing bacteria like Deferribacterales are particular to clays used for skin healing. In the present study it is proposed that healing properties of clay may be due to the microbes and microbial genes associated with metabolism of minerals like iron and sulphur, that lead to mineral acquisition in the Chamliyal's clay.

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