Recent Progress in Light Sheet Microscopy for Biological Applications

Single-Molecule Imaging in Living Drosophila Embryos with Reflected Light-Sheet Microscopy

(2016) Ferdinand Greiss et al.   BIOPHYSICAL JOURNAL

Rules and Self-Organizing Properties of Post-embryonic Plant Organ Cell Division Patterns

(2016) Daniel von Wangenheim et al.   CURRENT BIOLOGY

Light sheet fluorescence microscopy for in situ cell interaction analysis in mouse lymph nodes

(2016) Jun Abe et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Light-sheet imaging of mammalian development

(2016) Gustavo de Medeiros et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A crystal-clear zebrafish for in vivo imaging

(2016) Paride Antinucci et al.   Scientific Reports

3D print customized sample holders for live light sheet microscopy

(2015) Emeric Jeandupeux et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Light sheet-based fluorescence microscopy (LSFM) for the quantitative imaging of cells and tissues

(2015) Francesco Pampaloni et al.   CELL AND TISSUE RESEARCH

Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse

(2015) Alex T. Ritter et al.   IMMUNITY

Three-dimensional tracking of plus-tips by lattice light-sheet microscopy permits the quantification of microtubule growth trajectories within the mitotic apparatus

(2015) Norio Yamashita et al.   JOURNAL OF BIOMEDICAL OPTICS

3D Light-Sheet Fluorescence Microscopy of Cranial Neurons and Vasculature during Zebrafish Embryogenesis

(2015)   MOLECULES AND CELLS

Guide to light-sheet microscopy for adventurous biologists

(2015) Emmanuel G Reynaud et al.   NATURE METHODS

Whole-animal functional and developmental imaging with isotropic spatial resolution

(2015) Raghav K Chhetri et al.   NATURE METHODS

Preparation of plants for developmental and cellular imaging by light-sheet microscopy

(2015) Miroslav Ovečka et al.   Nature Protocols

Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

(2015) Etsuo A Susaki et al.   Nature Protocols

The unseen world: reflections on Leeuwenhoek (1677) 'Concerning little animals'

(2015) N. Lane   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Customized Light Sheet Microscope to Measure Spatio-Temporal Protein Dynamics in Small Model Organisms

(2015) Matthias Rieckher et al.   PLoS One

Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics

(2015) D. Li et al.   SCIENCE

Imaging the Zebrafish Dentition: From Traditional Approaches to Emerging Technologies

(2015) Bart Bruneel et al.   Zebrafish

Whole-central nervous system functional imaging in larval Drosophila

(2015) William C. Lemon et al.   Nature Communications

Dual-slit confocal light sheet microscopy for in vivo whole-brain imaging of zebrafish

(2015) Zhe Yang et al.   Biomedical Optics Express

Quantitative neuroanatomy of all Purkinje cells with light sheet microscopy and high-throughput image analysis

(2015) Ludovico Silvestri et al.   Frontiers in Neuroanatomy

Trans-Golgi network localized small GTPase RabA1d is involved in cell plate formation and oscillatory root hair growth

(2014) Tobias Berson et al.   BMC PLANT BIOLOGY

Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells

(2014) Jiji Chen et al.   CELL

iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging

(2014) Nicolas Renier et al.   CELL

Non-invasive long-term fluorescence live imaging of Tribolium castaneum embryos

(2014) F. Strobl et al.   DEVELOPMENT

Ligand Binding Shifts Highly Mobile Retinoid X Receptor to the Chromatin-Bound State in a Coactivator-Dependent Manner, as Revealed by Single-Cell Imaging

(2014) P. Brazda et al.   MOLECULAR AND CELLULAR BIOLOGY

Light-sheet functional imaging in fictively behaving zebrafish

(2014) Nikita Vladimirov et al.   NATURE METHODS

Fast, accurate reconstruction of cell lineages from large-scale fluorescence microscopy data

(2014) Fernando Amat et al.   NATURE METHODS

Functional organization of glomerular maps in the mouse accessory olfactory bulb

(2014) Gary F Hammen et al.   NATURE NEUROSCIENCE

3D live fluorescence imaging of cellular dynamics using Bessel beam plane illumination microscopy

(2014) Liang Gao et al.   Nature Protocols

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

(2014) Raju Tomer et al.   Nature Protocols

Dual-Color Fluorescence Cross-Correlation Spectroscopy on a Single Plane Illumination Microscope (SPIM-FCCS)

(2014) Jan Wolfgang Krieger et al.   OPTICS EXPRESS

Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution

(2014) Bi-Chang Chen et al.   SCIENCE

A Spatial Accommodation by Neighboring Cells Is Required for Organ Initiation in Arabidopsis

(2014) J. E. M. Vermeer et al.   SCIENCE

In-vivo Optical Tomography of Small Scattering Specimens: time-lapse 3D imaging of the head eversion process in Drosophila melanogaster

(2014) Alicia Arranz et al.   Scientific Reports

Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans

(2014) Jennifer T Wang et al.   eLife

3D imaging of Sox2 enhancer clusters in embryonic stem cells

(2014) Zhe Liu et al.   eLife

Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions

(2013) F. M. Coelho et al.   BLOOD

Genetically Targeted Optical Electrophysiology in Intact Neural Circuits

(2013) Guan Cao et al.   CELL

High-resolution deep imaging of live cellular spheroids with light-sheet-based fluorescence microscopy

(2013) Francesco Pampaloni et al.   CELL AND TISSUE RESEARCH

Fast Measurement of Sarcomere Length and Cell Orientation in Langendorff-Perfused Hearts Using Remote Focusing Microscopy

(2013) Edward J. Botcherby et al.   CIRCULATION RESEARCH

An Auxin Transport Mechanism Restricts Positive Orthogravitropism in Lateral Roots

(2013) Michel Ruiz Rosquete et al.   CURRENT BIOLOGY

ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue

(2013) T. Kuwajima et al.   DEVELOPMENT

Nanosecond ratio imaging of redox states in tumor cell spheroids using light sheet-based fluorescence microscopy

(2013) Sarah Schickinger et al.   JOURNAL OF BIOMEDICAL OPTICS

Light Sheet Microscopy for Tracking Single Molecules on the Apical Surface of Living Cells

(2013) Yu Li et al.   JOURNAL OF PHYSICAL CHEMISTRY B

In vivo imaging of zebrafish embryogenesis

(2013) Philipp J. Keller   METHODS

Structural and molecular interrogation of intact biological systems

(2013) Kwanghun Chung et al.   NATURE

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Whole-brain functional imaging at cellular resolution using light-sheet microscopy

(2013) Misha B Ahrens et al.   NATURE METHODS

Single-molecule imaging of transcription factor binding to DNA in live mammalian cells

(2013) J Christof M Gebhardt et al.   NATURE METHODS

SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction

(2013) Meng-Tsen Ke et al.   NATURE NEUROSCIENCE

Calcium Dynamics in Root Cells of Arabidopsis thaliana Visualized with Selective Plane Illumination Microscopy

(2013) Alex Costa et al.   PLoS One

Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy

(2013) Z. W. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lateral root morphogenesis is dependent on the mechanical properties of the overlaying tissues

(2013) M. Lucas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast functional imaging of multiple brain regions in intact zebrafish larvae using Selective Plane Illumination Microscopy

(2013) Thomas Panier et al.   Frontiers in Neural Circuits

High-speed panoramic light-sheet microscopy reveals global endodermal cell dynamics

(2013) Benjamin Schmid et al.   Nature Communications

Noninvasive Imaging beyond the Diffraction Limit of 3D Dynamics in Thickly Fluorescent Specimens

(2012) Liang Gao et al.   CELL

Quantitative Measurements in 3-Dimensional Datasets of Mouse Lymph Nodes Resolve Organ-Wide Functional Dependencies

(2012) Jürgen Mayer et al.   Computational and Mathematical Methods in Medicine

Mapping immune processes in intact tissues at cellular resolution

(2012) Christian Brede et al.   JOURNAL OF CLINICAL INVESTIGATION

Omnidirectional microscopy

(2012) Michael Weber et al.   NATURE METHODS

Multiview light-sheet microscope for rapid in toto imaging

(2012) Uros Krzic et al.   NATURE METHODS

Quantitative high-speed imaging of entire developing embryos with simultaneous multiview light-sheet microscopy

(2012) Raju Tomer et al.   NATURE METHODS

Three-dimensional imaging of solvent-cleared organs using 3DISCO

(2012) Ali Ertürk et al.   Nature Protocols

Confocal light sheet microscopy: micron-scale neuroanatomy of the entire mouse brain

(2012) L. Silvestri et al.   OPTICS EXPRESS

Nuclear export of single native mRNA molecules observed by light sheet fluorescence microscopy

(2012) J. P. Siebrasse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STED-SPIM: Stimulated Emission Depletion Improves Sheet Illumination Microscopy Resolution

(2011) Mike Friedrich et al.   BIOPHYSICAL JOURNAL

Intravital Imaging

(2011) Mikael J. Pittet et al.   CELL

Light sheet microscopy for real-time developmental biology

(2011) Michael Weber et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Quantitative fluorescence imaging of protein diffusion and interaction in living cells

(2011) Jérémie Capoulade et al.   NATURE BIOTECHNOLOGY

Live-cell 3D super-resolution imaging in thick biological samples

(2011) Francesca Cella Zanacchi et al.   NATURE METHODS

Long-term single-cell imaging of mammalian stem cells

(2011) Timm Schroeder   NATURE METHODS

Deep and fast live imaging with two-photon scanned light-sheet microscopy

(2011) Thai V Truong et al.   NATURE METHODS

Rapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination

(2011) Thomas A Planchon et al.   NATURE METHODS

Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain

(2011) Hiroshi Hama et al.   NATURE NEUROSCIENCE

Three-dimensional Fluorescence Lifetime Imaging with a Single Plane Illumination Microscope provides an improved Signal to Noise Ratio

(2011) Klaus Greger et al.   OPTICS EXPRESS

High-resolution live imaging of plant growth in near physiological bright conditions using light sheet fluorescence microscopy

(2011) Alexis Maizel et al.   PLANT JOURNAL

Quantitation of Cellular Dynamics in Growing Arabidopsis Roots with Light Sheet Microscopy

(2011) Giovanni Sena et al.   PLoS One

Electrical Spiking in Escherichia coli Probed with a Fluorescent Voltage-Indicating Protein

(2011) Joel M. Kralj et al.   SCIENCE

Live cell division dynamics monitoring in 3D large spheroid tumor models using light sheet microscopy

(2011) Corinne Lorenzo et al.   Cell Division

Measurement and analysis of sarcomere length in rat cardiomyocytes in situ and in vitro

(2010) G. Bub et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Reconstructing embryonic development

(2010) Khaled Khairy et al.   GENESIS

Going deeper than microscopy: the optical imaging frontier in biology

(2010) Vasilis Ntziachristos   NATURE METHODS

Fast, high-contrast imaging of animal development with scanned light sheet–based structured-illumination microscopy

(2010) Philipp J Keller et al.   NATURE METHODS

Single Plane Illumination Fluorescence Correlation Spectroscopy (SPIM-FCS) probes inhomogeneous three-dimensional environments

(2010) Thorsten Wohland et al.   OPTICS EXPRESS

A simple scanless two-photon fluorescence microscope using selective plane illumination

(2010) Jonathan Palero et al.   OPTICS EXPRESS

Light Sheet Microscopy for Single Molecule Tracking in Living Tissue

(2010) Jörg Gerhard Ritter et al.   PLoS One

Quantitative in vivo imaging of entire embryos with Digital Scanned Laser Light Sheet Fluorescence Microscopy

(2009) Philipp J Keller et al.   CURRENT OPINION IN NEUROBIOLOGY

Cisternal Organization of the Endoplasmic Reticulum during Mitosis

(2009) Lei Lu et al.   MOLECULAR BIOLOGY OF THE CELL

Association between active genes occurs at nuclear speckles and is modulated by chromatin environment

(2008) Jill M. Brown et al.   JOURNAL OF CELL BIOLOGY

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

(2008) Christian Eggeling et al.   NATURE

High-density mapping of single-molecule trajectories with photoactivated localization microscopy

(2008) Suliana Manley et al.   NATURE METHODS

Fast Three-Dimensional Fluorescence Imaging of Activity in Neural Populations by Objective-Coupled Planar Illumination Microscopy

(2008) Terrence F. Holekamp et al.   NEURON

Reconstruction of Zebrafish Early Embryonic Development by Scanned Light Sheet Microscopy

(2008) P. J. Keller et al.   SCIENCE

Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy

(2008) B. Huang et al.   SCIENCE

Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy

(2008) L. Schermelleh et al.   SCIENCE