High-resolution deep imaging of live cellular spheroids with light-sheet-based fluorescence microscopy

Three-Dimensional Microtissue Assay for High-Throughput Cytotoxicity of Nanoparticles

(2012) Yang Luo et al.   ANALYTICAL CHEMISTRY

Therapeutic Exploitation of Apoptosis and Autophagy for Glioblastoma

(2012) Donat Kogel et al.   Anti-Cancer Agents in Medicinal Chemistry

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Multicellular tumor spheroid model to evaluate spatio-temporal dynamics effect of chemotherapeutics: application to the gemcitabine/CHK1 inhibitor combination in pancreatic cancer

(2012) Isabelle Dufau et al.   BMC CANCER

Development of Multicellular Tumor Spheroid (MCTS) Culture from Breast Cancer Cell and a High Throughput Screening Method Using the MTT Assay

(2012) Wan Yong Ho et al.   PLoS One

Continuously perfused microbubble array for 3D tumor spheroid model

(2011) Sivaprakash Agastin et al.   Biomicrofluidics

STED-SPIM: Stimulated Emission Depletion Improves Sheet Illumination Microscopy Resolution

(2011) Mike Friedrich et al.   BIOPHYSICAL JOURNAL

Glioblastoma-Derived Epidermal Growth Factor Receptor Carboxyl-Terminal Deletion Mutants Are Transforming and Are Sensitive to EGFR-Directed Therapies

(2011) J. Cho et al.   CANCER RESEARCH

Nuclei of chicken neurons in tissues and three-dimensional cell cultures are organized into distinct radial zones

(2011) Doris Berchtold et al.   CHROMOSOME RESEARCH

Normal atmospheric oxygen tension and the use of antioxidants improve hepatocyte spheroid viability and function

(2011) Joseph B. Lillegard et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Light exposure and cell viability in fluorescence microscopy

(2011) H. SCHNECKENBURGER et al.   JOURNAL OF MICROSCOPY

Isolation and in vitro expansion of human colonic stem cells

(2011) Peter Jung et al.   NATURE MEDICINE

Rapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination

(2011) Thomas A Planchon et al.   NATURE METHODS

Direct stochastic optical reconstruction microscopy with standard fluorescent probes

(2011) Sebastian van de Linde et al.   Nature Protocols

Three-dimensional Fluorescence Lifetime Imaging with a Single Plane Illumination Microscope provides an improved Signal to Noise Ratio

(2011) Klaus Greger et al.   OPTICS EXPRESS

High-resolution live imaging of plant growth in near physiological bright conditions using light sheet fluorescence microscopy

(2011) Alexis Maizel et al.   PLANT JOURNAL

Quantitation of Cellular Dynamics in Growing Arabidopsis Roots with Light Sheet Microscopy

(2011) Giovanni Sena et al.   PLoS One

Kidney Spheroids Recapitulate Tubular Organoids Leading to Enhanced Tubulogenic Potency of Human Kidney-Derived Cells

(2011) Ella Buzhor et al.   TISSUE ENGINEERING PART A

Exploiting the balance between life and death: Targeted cancer therapy and “oncogenic shock”

(2010) Sreenath V. Sharma et al.   BIOCHEMICAL PHARMACOLOGY

Bioengineered 3D platform to explore cell–ECM interactions and drug resistance of epithelial ovarian cancer cells

(2010) Daniela Loessner et al.   BIOMATERIALS

Searching for a cure: Gene therapy for glioblastoma

(2010) Paul Dent et al.   CANCER BIOLOGY & THERAPY

3D collagen type I matrix inhibits the antimigratory effect of doxorubicin

(2010) Emilie Millerot-Serrurot et al.   Cancer Cell International

Synergistic Enhancement of Carboplatin Efficacy with Photodynamic Therapy in a Three-Dimensional Model for Micrometastatic Ovarian Cancer

(2010) I. Rizvi et al.   CANCER RESEARCH

Laminin regulates PI3K basal localization and activation to sustain STAT5 activation

(2010) Ren Xu et al.   CELL CYCLE

Epigenetic Modifications in 3D: Nuclear Organization of the Differentiating Mammary Epithelial Cell

(2010) Clémence Kress et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Gene Expression in the Third Dimension: The ECM-nucleus Connection

(2010) Virginia A. Spencer et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Multiphoton fluorescence lifetime imaging of 3D-stem cell spheroids during differentiation

(2010) Karsten König et al.   MICROSCOPY RESEARCH AND TECHNIQUE

A distinctive role for focal adhesion proteins in three-dimensional cell motility

(2010) Stephanie I. Fraley et al.   NATURE CELL BIOLOGY

Software for bead-based registration of selective plane illumination microscopy data

(2010) Stephan Preibisch et al.   NATURE METHODS

Fast, high-contrast imaging of animal development with scanned light sheet–based structured-illumination microscopy

(2010) Philipp J Keller et al.   NATURE METHODS

Single Plane Illumination Fluorescence Correlation Spectroscopy (SPIM-FCS) probes inhomogeneous three-dimensional environments

(2010) Thorsten Wohland et al.   OPTICS EXPRESS

A line scanned light-sheet microscope with phase shaped self-reconstructing beams

(2010) Florian O. Fahrbach et al.   OPTICS EXPRESS

Light Sheet Microscopy for Single Molecule Tracking in Living Tissue

(2010) Jörg Gerhard Ritter et al.   PLoS One

Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties

(2010) T. J. Bartosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Madin-Darby canine kidney cells are increased in aerobic glycolysis when cultured on flat and stiff collagen-coated surfaces rather than in physiological 3-D cultures

(2010) Francesco Pampaloni et al.   PROTEOMICS

Optogenetic Control of Cardiac Function

(2010) A. B. Arrenberg et al.   SCIENCE

Globally optimal stitching of tiled 3D microscopic image acquisitions

(2009) S. Preibisch et al.   BIOINFORMATICS

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

(2009) Britta Weigelt et al.   BREAST CANCER RESEARCH AND TREATMENT

Selective plane illumination microscopy techniques in developmental biology

(2009) J. Huisken et al.   DEVELOPMENT

Dynamic Three-Dimensional Culture Methods Enhance Mesenchymal Stem Cell Properties and Increase Therapeutic Potential

(2009) Jessica E. Frith et al.   TISSUE ENGINEERING PART C-METHODS

Biodegradable poly(ethylene glycol)–peptide hydrogels with well-defined structure and properties for cell delivery

(2008) Shao Qiong Liu et al.   BIOMATERIALS

Culturing of Human Mesenchymal Stem Cells as Three-dimensional Aggregates Induces Functional Expression of CXCR4 That Regulates Adhesion to Endothelial Cells

(2008) Irina A. Potapova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ultramicroscopy: 3D reconstruction of large microscopical specimens

(2008) K. Becker et al.   Journal of Biophotonics

Fast Three-Dimensional Fluorescence Imaging of Activity in Neural Populations by Objective-Coupled Planar Illumination Microscopy

(2008) Terrence F. Holekamp et al.   NEURON

Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab

(2008) M Pickl et al.   ONCOGENE

Reconstruction of Zebrafish Early Embryonic Development by Scanned Light Sheet Microscopy

(2008) P. J. Keller et al.   SCIENCE