Diversified transporters and pathways for bacteriocin secretion in gram-positive bacteria

Controlled functional expression of the bacteriocins pediocin PA-1 and bactofencin A in Escherichia coli

(2017) Beatriz Mesa-Pereira et al.   Scientific Reports

Novel Group of Leaderless Multipeptide Bacteriocins from Gram-Positive Bacteria

(2016) Kirill V. Ovchinnikov et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Insights into the Biosynthesis of Duramycin

(2016) Liujie Huo et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Structure and Substrate Recognition of the Bottromycin Maturation Enzyme BotP

(2016) Greg Mann et al.   CHEMBIOCHEM

An α/β-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization

(2016) Qingfei Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expanded Natural Product Diversity Revealed by Analysis of Lanthipeptide-Like Gene Clusters in Actinobacteria

(2015) Qi Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Pediocin PA-1 Accessory Protein Ensures Correct Disulfide Bond Formation in the Antimicrobial Peptide Pediocin PA-1

(2015) Camilla Oppegård et al.   BIOCHEMISTRY

Functional Analysis of Genes Involved in the Biosynthesis of Enterocin NKR-5-3B, a Novel Circular Bacteriocin

(2015) Rodney H. Perez et al.   JOURNAL OF BACTERIOLOGY

Biosynthesis and Transport of the Lantibiotic Mutacin 1140 Produced by Streptococcus mutans

(2015) Jerome Escano et al.   JOURNAL OF BACTERIOLOGY

Crystal structures of a polypeptide processing and secretion transporter

(2015) David Yin-wei Lin et al.   NATURE

Substrate Specificity of the Lanthipeptide Peptidase ElxP and the Oxidoreductase ElxO

(2014) Manuel A. Ortega et al.   ACS Chemical Biology

Circular Bacteriocins: Biosynthesis and Mode of Action

(2014) Christina Gabrielsen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria

(2014) Anne-Catrin Letzel et al.   BMC GENOMICS

Genome Mining Reveals a Minimum Gene Set for the Biosynthesis of 32-Membered Macrocyclic Thiopeptides Lactazoles

(2014) Shohei Hayashi et al.   CHEMISTRY & BIOLOGY

Structure and protective efficacy of the Staphylococcus aureus autocleaving protease EpiP

(2014) Misty L. Kuhn et al.   FASEB JOURNAL

Structure of the nisin leader peptidase NisP revealing a C-terminal autocleavage activity

(2014) Yueyang Xu et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Boundary of the Nucleotide-Binding Domain of Streptococcus ComA Based on Functional and Structural Analysis

(2013) Seiji Ishii et al.   BIOCHEMISTRY

Sec-secretion and sortase-mediated anchoring of proteins in Gram-positive bacteria

(2013) Olaf Schneewind et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Generation of an actagardine A variant library through saturation mutagenesis

(2012) Steven Boakes et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Synthetic Biotechnology to Study and Engineer Ribosomal Bottromycin Biosynthesis

(2012) Liujie Huo et al.   CHEMISTRY & BIOLOGY

ABC transporters of antimicrobial peptides in Firmicutes bacteria - phylogeny, function and regulation

(2012) Susanne Gebhard   MOLECULAR MICROBIOLOGY

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

(2012) Paul G. Arnison et al.   NATURAL PRODUCT REPORTS

The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A

(2012) Leif Flühe et al.   Nature Chemical Biology

Bacteriocins — a viable alternative to antibiotics?

(2012) Paul D. Cotter et al.   NATURE REVIEWS MICROBIOLOGY

Structure and Biosynthesis of the Antibiotic Bottromycin D

(2012) Yanpeng Hou et al.   ORGANIC LETTERS

Posttranslational β-methylation and macrolactamidination in the biosynthesis of the bottromycin complex of ribosomal peptide antibiotics

(2012) Juan Pablo Gomez-Escribano et al.   Chemical Science

Biosynthesis of the Antimicrobial Peptide Epilancin 15X and Its N-Terminal Lactate

(2011) Juan E. Velásquez et al.   CHEMISTRY & BIOLOGY

Lantibiotic Transporter Requires Cooperative Functioning of the Peptidase Domain and the ATP Binding Domain

(2011) Mami Nishie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of the thiazolyl peptide GE37468 gene cluster fromStreptomycesATCC 55365 and heterologous expression inStreptomyces lividans

(2011) Travis S. Young et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome mining for ribosomally synthesized natural products

(2010) Juan E Velásquez et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Crystal Structure of the Peptidase Domain ofStreptococcusComA, a Bifunctional ATP-binding Cassette Transporter Involved in the Quorum-sensing Pathway

(2010) Seiji Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Manipulation of Thiocillin Variants by Prepeptide Gene Replacement: Structure, Conformation, and Activity of Heterocycle Substitution Mutants

(2010) Albert A. Bowers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides

(2010) J. Claesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile

(2010) M. C. Rea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cloning and Characterization of the Gene Cluster Involved in the Production of the Circular Bacteriocin Carnocyclin A

(2010) Marco J. van Belkum et al.   Probiotics and Antimicrobial Proteins

Structure Determination and Total Synthesis of Bottromycin A2: A Potent Antibiotic against MRSA and VRE

(2009) Hiroyuki Shimamura et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular and Genetic Characterization of a Novel Bacteriocin Locus in Enterococcus avium Isolates from Infants

(2009) D. J. Birri et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biosynthesis and transcriptional analysis of thurincin H, a tandem repeated bacteriocin genetic locus, produced byBacillus thuringiensisSF361

(2009) Hyungjae Lee et al.   FEMS MICROBIOLOGY LETTERS

ATP-dependent leader peptide cleavage by NukT, a bifunctional ABC transporter, during lantibiotic biosynthesis

(2009) Mami Nishie et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Follow the leader: the use of leader peptides to guide natural product biosynthesis

(2009) Trent J Oman et al.   Nature Chemical Biology

Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin

(2009) Laura C. Wieland Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Contributions of the Nisin Biosynthesis Enzymes NisB and NisC and Transporter NisT to Prenisin Production by Lactococcus lactis

(2008) H. B. van den Berg van Saparoea et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Corynebacterium glutamicum possesses two secA homologous genes that are essential for viability

(2008) Michael Caspers et al.   ARCHIVES OF MICROBIOLOGY

In VitroReconstitution and Substrate Specificity of a Lantibiotic Protease†

(2008) L. A. Furgerson Ihnken et al.   BIOCHEMISTRY

The Importance of the Leader Sequence for Directing Lanthionine Formation in Lacticin 481†

(2008) Gregory C. Patton et al.   BIOCHEMISTRY