Toll-like receptor signaling in parasitic infections

Topical Resiquimod Protects against Visceral Infection with Leishmania infantum chagasi in Mice

(2014) Noah Craft et al.   Clinical and Vaccine Immunology

Recruitment and Endo-Lysosomal Activation of TLR9 in Dendritic Cells Infected with Trypanosoma cruzi

(2014) D. C. Bartholomeu et al.   JOURNAL OF IMMUNOLOGY

Tick Saliva Inhibits Dendritic Cell Migration, Maturation, and Function while Promoting Development of Th2 Responses

(2014) Anna Skallová et al.   JOURNAL OF IMMUNOLOGY

TLR9-Dependent Activation of Dendritic Cells by DNA from Leishmania major Favors Th1 Cell Development and the Resolution of Lesions

(2014) F. Hkima Abou Fakher et al.   JOURNAL OF IMMUNOLOGY

Leishmania aethiopica Field Isolates Bearing an Endosymbiontic dsRNA Virus Induce Pro-inflammatory Cytokine Response

(2014) Haroun Zangger et al.   PLoS Neglected Tropical Diseases

A study of immunomodulatory genes responses to macrophages of Schistosoma japonicum infection during different stages by microarray analysis

(2013) Po-Ching Cheng et al.   ACTA TROPICA

Leishmaniaexpressed lipophosphoglycan interacts with Toll-like receptor (TLR)-2 to decrease TLR-9 expression and reduce anti-leishmanial responses

(2013) S. Srivastava et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

UNC93B1 and Nucleic Acid-sensing Toll-like Receptors Mediate Host Resistance to Infection withLeishmania major

(2013) Bruno Luiz Fonseca Schamber-Reis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of tick saliva on signalling pathways activated by TLR-2 ligand and Borrelia afzelii in dendritic cells

(2012) J. LIESKOVSKA et al.   PARASITE IMMUNOLOGY

Ixodes scapularis saliva mitigates inflammatory cytokine secretion during Anaplasma phagocytophilum stimulation of immune cells

(2012) Gang Chen et al.   Parasites & Vectors

Dissecting negative regulation of Toll-like receptor signaling

(2012) Takeshi Kondo et al.   TRENDS IN IMMUNOLOGY

Pathogen-Derived Oligosaccharides Improve Innate Immune Response to Intracellular Parasite Infection

(2011) Alex Osanya et al.   AMERICAN JOURNAL OF PATHOLOGY

Human Schistosomiasis Is Associated with Endotoxemia and Toll-Like Receptor 2- and 4-Bearing B Cells

(2011) Daniel Onguru et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Human cutaneous leishmaniasis: interferon-dependent expression of double-stranded RNA-dependent protein kinase (PKR) via TLR2

(2011) Áislan de Carvalho Vivarini et al.   FASEB JOURNAL

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Pathogenic bacteria prime the induction of Toll-like receptor signalling in human colonic cells by the Gal/GalNAc lectin Carbohydrate Recognition Domain of Entamoeba histolytica

(2011) José Manuel Galván-Moroyoqui et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Deconstructing Tick Saliva

(2011) Carlo José F. Oliveira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requirement of UNC93B1 Reveals a Critical Role for TLR7 in Host Resistance to Primary Infection with Trypanosoma cruzi

(2011) B. C. Caetano et al.   JOURNAL OF IMMUNOLOGY

Effect of tick saliva on immune interactions between Borrelia afzelii and murine dendritic cells

(2011) M. SLÁMOVÁ et al.   PARASITE IMMUNOLOGY

Toll-like receptor activation by helminths or helminth products to alleviate inflammatory bowel disease

(2011) ShuMin Sun et al.   Parasites & Vectors

Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria

(2011) Bernardo S. Franklin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leishmania RNA Virus Controls the Severity of Mucocutaneous Leishmaniasis

(2011) A. Ives et al.   SCIENCE

Pattern Recognition Receptors and the Innate Immune Response to Viral Infection

(2011) Mikayla R. Thompson et al.   Viruses-Basel

Critical Role of IRF-5 in the Development of T helper 1 responses to Leishmania donovani infection

(2011) Andrea Paun et al.   PLoS Pathogens

Insights into the role of Toll-like receptors in modulation of T cell responses

(2010) Raveendra Kulkarni et al.   CELL AND TISSUE RESEARCH

Cystatin cures visceral leishmaniasis by NF-κB-mediated proinflammatory response through co-ordination of TLR/MyD88 signaling with p105-Tpl2-ERK pathway

(2010) Susanta Kar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Important aspects of Toll-like receptors, ligands and their signaling pathways

(2010) Z. L. Chang   INFLAMMATION RESEARCH

Proinflammatory Clearance of Apoptotic Neutrophils Induces an IL-12lowIL-10high Regulatory Phenotype in Macrophages

(2010) A. A. Filardy et al.   JOURNAL OF IMMUNOLOGY

Applying TLR Synergy in Immunotherapy: Implications in Cutaneous Leishmaniasis

(2010) V. S. Raman et al.   JOURNAL OF IMMUNOLOGY

Protein-DNA Complex Is the Exclusive Malaria Parasite Component That Activates Dendritic Cells and Triggers Innate Immune Responses

(2010) X. Wu et al.   JOURNAL OF IMMUNOLOGY

Prophylactic and therapeutic implications of toll-like receptor ligands

(2010) Mona Hedayat et al.   MEDICINAL RESEARCH REVIEWS

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Toll-like receptor (TLR) 2 and TLR4 deficiencies exert differential in vivo effects against Schistosoma japonicum

(2010) M. ZHANG et al.   PARASITE IMMUNOLOGY

Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes

(2010) Kelly L Johnston et al.   Parasites & Vectors

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Macroparasites, innate immunity and immunoregulation: developing natural models

(2010) Ida M. Friberg et al.   TRENDS IN PARASITOLOGY

Combined TLR2 and TLR4 ligation in the context of bacterial or helminth extracts in human monocyte derived dendritic cells: molecular correlates for Th1/Th2 polarization

(2009) Elly van Riet et al.   BMC IMMUNOLOGY

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

TLRs and chronic inflammation

(2009) Caroline Ospelt et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Helminth Cysteine Proteases Inhibit TRIF-dependent Activation of Macrophages via Degradation of TLR3

(2009) Sheila Donnelly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preventive effects ofSchistosoma japonicumova on trinitrobenzenesulfonic acid-induced colitis and bacterial translocation in mice

(2009) Yuan Zhao et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7

(2009) Tomoko Hayashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Community Variation in Human Body Habitats Across Space and Time

(2009) E. K. Costello et al.   SCIENCE

Tick saliva induces regulatory dendritic cells: MAP-kinases and Toll-like receptor-2 expression as potential targets

(2009) Carlo José F. Oliveira et al.   VETERINARY PARASITOLOGY

Attenuation of Toll-Like Receptor Expression and Function in Latent Tuberculosis by Coexistent Filarial Infection with Restoration Following Antifilarial Chemotherapy

(2009) Subash Babu et al.   PLoS Neglected Tropical Diseases

Role of toll-like receptors in tissue repair and tumorigenesis

(2008) S. Rakoff-Nahoum et al.   BIOCHEMISTRY-MOSCOW

Inhibition of TLR3 and TLR4 function and expression in human dendritic cells by helminth parasites

(2008) R. T. Semnani et al.   BLOOD

Toll-like receptors expressed in tumor cells: targets for therapy

(2008) Li Yu et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Leishmania donovaniinfection down-regulates TLR2-stimulated IL-12p40 and activates IL-10 in cells of macrophage/monocytic lineage by modulating MAPK pathways through a contact-dependent mechanism

(2008) Dinesh Chandra et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Current Status of Vaccines for Schistosomiasis

(2008) D. P. McManus et al.   CLINICAL MICROBIOLOGY REVIEWS

Dermacentor variabilis: Regulation of fibroblast migration by tick salivary gland extract and saliva

(2008) Carolyn Kramer et al.   EXPERIMENTAL PARASITOLOGY

Activation and regulation of Toll-Like Receptors (TLRs) by helminth parasites

(2008) Priyanka Goel Venugopal et al.   IMMUNOLOGIC RESEARCH

Leishmania pifanoi Proteoglycolipid Complex P8 Induces Macrophage Cytokine Production through Toll-Like Receptor 4

(2008) S. M. Whitaker et al.   INFECTION AND IMMUNITY

Immunization with a Toll-Like Receptor 7 and/or 8 Agonist Vaccine Adjuvant Increases Protective Immunity against Leishmania major in BALB/c Mice

(2008) W.-W. Zhang et al.   INFECTION AND IMMUNITY

Enhanced Immunogenicity of Plasmodium falciparum Peptide Vaccines Using a Topical Adjuvant Containing a Potent Synthetic Toll-Like Receptor 7 Agonist, Imiquimod

(2008) C. Othoro et al.   INFECTION AND IMMUNITY

Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling

(2008) Wangsen Cao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toll-like receptors, wound healing, and carcinogenesis

(2008) Johannes Kluwe et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain–containing proteins

(2008) Christine Cirl et al.   NATURE MEDICINE

Salivating for Knowledge: Potential Pharmacological Agents in Tick Saliva

(2008) Joppe W. R Hovius et al.   PLOS MEDICINE