Mechanochemical Rhodium(III)- and Gold(I)-Catalyzed C−H Bond Alkynylations of Indoles under Solventless Conditions in Mixer Mills

Increasing Catalyst Efficiency in C−H Activation Catalysis

(2018) Tobias Gensch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidative Mechanochemistry: Direct, Room-Temperature, Solvent-Free Conversion of Palladium and Gold Metals into Soluble Salts and Coordination Complexes

(2018) Jean-Louis Do et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

From Synthesis of Amino Acids and Peptides to Enzymatic Catalysis: A Bottom-Up Approach in Mechanochemistry

(2018) Carsten Bolm et al.   ChemSusChem

Mechanochemistry and organic synthesis: from mystical to practical

(2018) J. Andersen et al.   GREEN CHEMISTRY

Recent advances in mechanochemical C–H functionalization reactions

(2018) Shujuan Zhao et al.   TETRAHEDRON LETTERS

Mechanochemistry as an emerging tool for molecular synthesis: what can it offer?

(2018) Joseph L. Howard et al.   Chemical Science

Multicomponent mechanochemical synthesis

(2018) Marco Leonardi et al.   Chemical Science

Mechanochemical Cobalt-Catalyzed C−H Bond Functionalizations by Ball Milling

(2018) Hanchao Cheng et al.   ADVANCED SYNTHESIS & CATALYSIS

Mechanochemistry for Organic Chemists: An Update

(2017) Davin Tan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A3 -Coupling Reaction and [Ag(IPr)2 ]PF6 : A Successful Couple

(2017) Audrey Beillard et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Mechanochemical indole synthesis by rhodium-catalysed oxidative coupling of acetanilides and alkynes under solventless conditions in a ball mill

(2017) Gary N. Hermann et al.   GREEN CHEMISTRY

Altering Product Selectivity by Mechanochemistry

(2017) José G. Hernández et al.   JOURNAL OF ORGANIC CHEMISTRY

Cobalt(III)-Catalyzed Fast and Solvent-Free C–H Allylation of Indoles Using Mechanochemistry

(2017) Xinpeng Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanochemistry for facilitated access to N,N-diaryl NHC metal complexes

(2017) Audrey Beillard et al.   NEW JOURNAL OF CHEMISTRY

Mechanochemical Ruthenium-Catalyzed Hydroarylations of Alkynes under Ball-Milling Conditions

(2017) Hanchao Cheng et al.   ORGANIC LETTERS

Cu(0), O2 and mechanical forces: a saving combination for efficient production of Cu–NHC complexes

(2017) Audrey Beillard et al.   Chemical Science

Beyond C2 and C3: Transition-Metal-Catalyzed C–H Functionalization of Indole

(2017) Jamie A. Leitch et al.   ACS Catalysis

Mechanochemical Rhodium(III)-Catalyzed C–H Bond Amidation of Arenes with Dioxazolones under Solventless Conditions in a Ball Mill

(2017) Gary N. Hermann et al.   ACS Catalysis

Mechanochemical Iridium(III)-Catalyzed C−H Bond Amidation of Benzamides with Sulfonyl Azides under Solvent-Free Conditions in a Ball Mill

(2016) Gary N. Hermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-catalyzed annulation of arenes with alkynes through weak chelation-assisted C–H activation

(2016) Yudong Yang et al.   CHEMICAL COMMUNICATIONS

Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs)

(2016) Davin Tan et al.   CHEMICAL COMMUNICATIONS

Mild metal-catalyzed C–H activation: examples and concepts

(2016) T. Gensch et al.   CHEMICAL SOCIETY REVIEWS

Mechanically Induced Fe(III) Catalysis at Room Temperature: Solvent-Free Cross-Dehydrogenative Coupling of 3-Benzylic Indoles with Methylenes/Indoles

(2016) Jing-Bo Yu et al.   JOURNAL OF ORGANIC CHEMISTRY

Liquid-Assisted Grinding Accelerating: Suzuki–Miyaura Reaction of Aryl Chlorides under High-Speed Ball-Milling Conditions

(2016) Zhi-Jiang Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanochemically Activated Oxidative Coupling of Indoles with Acrylates through C–H Activation: Synthesis of 3-Vinylindoles and β,β-Diindolyl Propionates and Study of the Mechanism

(2016) Kan-Yan Jia et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanochemical Synthesis of Extended Iptycenes

(2016) Yanchuan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium-Catalyzed C–H Alkynylation of Aromatic Amides with Hypervalent Iodine–Alkyne Reagents

(2016) Ramadoss Boobalan et al.   ORGANIC LETTERS

The Choice Is Yours: Using Liquid-Assisted Grinding To Choose between Products in the Palladium-Catalyzed Dimerization of Terminal Alkynes

(2016) Longrui Chen et al.   ACS Catalysis

Fast and Selective Dehydrogenative C–H/C–H Arylation Using Mechanochemistry

(2016) Shao-Jie Lou et al.   ACS Catalysis

Mechanochemistry: A Force of Synthesis

(2016) Jean-Louis Do et al.   ACS Central Science

Transition Metal-Catalyzed CH Activation of Indoles

(2015) Alexander H. Sandtorv   ADVANCED SYNTHESIS & CATALYSIS

Rhodium-Catalyzed Direct C7 Alkynylation of Indolines

(2015) Ning Jin et al.   ADVANCED SYNTHESIS & CATALYSIS

Mechanochemical Rhodium(III)-Catalyzed CH Bond Functionalization of Acetanilides under Solventless Conditions in a Ball Mill

(2015) Gary N. Hermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

OH-Directed Alkynylation of 2-Vinylphenols with Ethynyl Benziodoxolones: A Fast Access to Terminal 1,3-Enynes

(2015) Peter Finkbeiner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Inexpensive and Recyclable Silver-Foil Catalyst for the Cyclopropanation of Alkenes with Diazoacetates under Mechanochemical Conditions

(2015) Longrui Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

[Cp*RhCl2]2: mechanosynthesis and applications in C–H bond functionalisations under ball-milling conditions

(2015) José G. Hernández et al.   CHEMICAL COMMUNICATIONS

Fast, solvent-free, highly enantioselective three-component coupling of aldehydes, alkynes, and amines catalysed by the copper(ii)pybox complex under high-vibration ball-milling

(2015) Zhenhua Li et al.   GREEN CHEMISTRY

Iridium(III)-Catalyzed C-7 Selective C–H Alkynylation of Indolines at Room Temperature

(2015) Yunxiang Wu et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanochemical Ruthenium-Catalyzed Olefin Metathesis

(2015) Jean-Louis Do et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt(III)-Catalyzed C2-Selective C–H Alkynylation of Indoles

(2015) Zhuo-Zhuo Zhang et al.   ORGANIC LETTERS

Rh(III) and Ru(II)-Catalyzed Site-Selective C–H Alkynylation of Quinolones

(2015) Dahye Kang et al.   ORGANIC LETTERS

Indole synthesis through transition metal-catalyzed C–H activation

(2015) Tenglong Guo et al.   TETRAHEDRON LETTERS

Metal-catalyzed organic reactions using mechanochemistry

(2015) José G. Hernández et al.   TETRAHEDRON LETTERS

Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups

(2015) Zhengkai Chen et al.   Organic Chemistry Frontiers

Carboxylate-Directed CH Functionalization

(2014) Guangfa Shi et al.   ADVANCED SYNTHESIS & CATALYSIS

Formal SN-Type Reactions in Rhodium(III)-Catalyzed CH Bond Activation

(2014) Nadine Kuhl et al.   ADVANCED SYNTHESIS & CATALYSIS

Development of CN Coupling Using Mechanochemistry: Catalytic Coupling of Arylsulfonamides and Carbodiimides

(2014) Davin Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed CH Alkynylation of Arenes at Room Temperature

(2014) Chao Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Preparation of conjugated 1,3-enynes by Rh(iii)-catalysed alkynylation of alkenes via C–H activation

(2014) Karl D. Collins et al.   CHEMICAL COMMUNICATIONS

Mechanochemical C–H bond activation: rapid and regioselective double cyclopalladation monitored by in situ Raman spectroscopy

(2014) Marina Juribašić et al.   CHEMICAL COMMUNICATIONS

Rhodium(iii)-catalyzed olefinic C–H alkynylation of enamides at room temperature

(2014) Chao Feng et al.   CHEMICAL COMMUNICATIONS

A ball-milling strategy for the synthesis of benzothiazole, benzimidazole and benzoxazole derivatives under solvent-free conditions

(2014) Hemant Sharma et al.   GREEN CHEMISTRY

In(III) Triflate-Mediated Solvent-Free Synthesis and Activation of Thioglycosides by Ball Milling and Structural Analysis of Long Chain Alkyl Thioglycosides by TEM and Quantum Chemical Methods

(2014) Vajinder Kumar et al.   JOURNAL OF ORGANIC CHEMISTRY

Rh(III)- and Ir(III)-Catalyzed C–H Alkynylation of Arenes under Chelation Assistance

(2014) Fang Xie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed C–C Bond Formation of Quinoline N-Oxides at the C-8 Position under Mild Conditions

(2014) Jisu Jeong et al.   ORGANIC LETTERS

A Density Functional Theory (DFT) Mechanistic Study of Gold(I)-Catalyzed Alkynylation of the Indole and Pyrrole Substrates, Using a Hypervalent Iodine Reagent

(2014) Alireza Ariafard   ACS Catalysis

Mechanochemical milling promoted solvent-free imino Diels–Alder reaction catalyzed by FeCl3: diastereoselective synthesis of cis-2,4-diphenyl-1,2,3,4-tetrahydroquinolines

(2014) Ya-Jun Tan et al.   RSC Advances

Mechanosynthesis of pharmaceutically relevant sulfonyl-(thio)ureas

(2013) Davin Tan et al.   CHEMICAL COMMUNICATIONS

Mechanochemical organic synthesis

(2013) Guan-Wu Wang   CHEMICAL SOCIETY REVIEWS

Efficient ZnBr2-catalyzed reactions of allylic alcohols with indoles, sulfamides and anilines under high-speed vibration milling conditions

(2013) Guang-Peng Fan et al.   GREEN CHEMISTRY

Freedom: a copper-free, oxidant-free and solvent-free palladium catalysed homocoupling reaction

(2013) Longrui Chen et al.   GREEN CHEMISTRY

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Asymmetric direct aldol reactions catalyzed by chiral amine macrocycle–metal(ii) complexes under solvent-free conditions

(2013) Koichi Tanaka et al.   NEW JOURNAL OF CHEMISTRY

Fast, solvent-free asymmetric alkynylation of prochiral sp3 C–H bonds in a ball mill for the preparation of optically active tetrahydroisoquinoline derivatives

(2013) Jingbo Yu et al.   TETRAHEDRON LETTERS

Chelation-assisted Rh(iii)-catalyzed C2-selective oxidative C–H/C–H cross-coupling of indoles/pyrroles with heteroarenes

(2013) Xurong Qin et al.   Chemical Science

Controlling Site Selectivity in Palladium-Catalyzed C–H Bond Functionalization

(2012) Sharon R. Neufeldt et al.   ACCOUNTS OF CHEMICAL RESEARCH

Efficient and Versatile Synthesis of Indoles from Enamines and Imines by Cross-Dehydrogenative Coupling

(2012) Zhuangzhi Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Beyond Directing Groups: Transition-Metal-Catalyzed CH Activation of Simple Arenes

(2012) Nadine Kuhl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanically activated synthesis of (E)-stilbene derivatives by high-speed ball milling

(2012) Xingyi Zhu et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Poly(ethylene glycol) as reaction medium for mild Mizoroki–Heck reaction in a ball-mill

(2012) Valérie Declerck et al.   CHEMICAL COMMUNICATIONS

Copper-mediated oxidative direct C–C (hetero)aromatic cross-coupling

(2012) Koji Hirano et al.   CHEMICAL COMMUNICATIONS

Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization

(2012) Percia Beatrice Arockiam et al.   CHEMICAL REVIEWS

From C(sp2)–H to C(sp3)–H: systematic studies on transition metal-catalyzed oxidative C–C formation

(2012) Bi-Jie Li et al.   CHEMICAL SOCIETY REVIEWS

C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation

(2012) Guoyong Song et al.   CHEMICAL SOCIETY REVIEWS

Progress in palladium-based catalytic systems for the sustainable synthesis of annulated heterocycles: a focus on indole backbones

(2012) Mélanie Platon et al.   CHEMICAL SOCIETY REVIEWS

Ethynyl Benziodoxolones for the Direct Alkynylation of Heterocycles: Structural Requirement, Improved Procedure for Pyrroles, and Insights into the Mechanism

(2012) Jonathan P. Brand et al.   CHEMISTRY-A EUROPEAN JOURNAL

Suzuki cross-couplings of (hetero)aryl chlorides in the solid-state

(2012) Giancarlo Cravotto et al.   NEW JOURNAL OF CHEMISTRY

Indole synthesis – something old, something new

(2012) Martyn Inman et al.   Chemical Science

Rhodium Catalyzed Chelation-Assisted C–H Bond Functionalization Reactions

(2011) Denise A. Colby et al.   ACCOUNTS OF CHEMICAL RESEARCH

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Fast, ligand- and solvent-free copper-catalyzed click reactions in a ball mill

(2011) Rico Thorwirth et al.   CHEMICAL COMMUNICATIONS

Update 1 of: Synthesis and Functionalization of Indoles Through Palladium-Catalyzed Reactions

(2011) Sandro Cacchi et al.   CHEMICAL REVIEWS

Ball milling in organic synthesis: solutions and challenges

(2011) Achim Stolle et al.   CHEMICAL SOCIETY REVIEWS

Mechanochemistry: opportunities for new and cleaner synthesis

(2011) Stuart L. James et al.   CHEMICAL SOCIETY REVIEWS

Fast, Ligand- and Solvent-Free Synthesis of 1,4-Substituted Buta-1,3-diynes by Cu-Catalyzed Homocoupling of Terminal Alkynes in a Ball Mill

(2011) Robert Schmidt et al.   CHEMISTRY-A EUROPEAN JOURNAL

Solvent-Free Cross-Dehydrogenative Coupling Reactions under High Speed Ball-Milling Conditions Applied to the Synthesis of Functionalized Tetrahydroisoquinolines

(2011) Weike Su et al.   JOURNAL OF ORGANIC CHEMISTRY

Solvent-free reactions of alkynes in ball mills: It is definitely more than mixing

(2011) Achim Stolle et al.   PURE AND APPLIED CHEMISTRY

Indole synthesis: a review and proposed classification

(2011) Douglass F. Taber et al.   TETRAHEDRON

Fast copper-, ligand- and solvent-free Sonogashira coupling in a ball mill

(2010) Rico Thorwirth et al.   GREEN CHEMISTRY

Rh Catalyzed Olefination and Vinylation of Unactivated Acetanilides

(2010) Frederic W. Patureau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Alkynylation of Indole and Pyrrole Heterocycles

(2009) Jonathan P. Brand et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Solvent-free Sonogashira coupling reaction via high speed ball milling

(2009) Dennis A. Fulmer et al.   GREEN CHEMISTRY

Organocatalytic reactions: effects of ball milling, microwave and ultrasound irradiation

(2008) Angelika Bruckmann et al.   GREEN CHEMISTRY