Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis

Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes

(2016) Nicolai J. Wewer Albrechtsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The biology of glucagon and the consequences of hyperglucagonemia

(2016) Nicolai J Wewer Albrechtsen et al.   Biomarkers in Medicine

Acute disruption of glucagon secretion or action does not improve glucose tolerance in an insulin-deficient mouse model of diabetes

(2015) Vivi R. Steenberg et al.   DIABETOLOGIA

Lack of glucagon receptor signaling and its implications beyond glucose homeostasis

(2015) M. J. Charron et al.   JOURNAL OF ENDOCRINOLOGY

Pancreatic alpha-cells from female mice undergo morphofunctional changes during compensatory adaptations of the endocrine pancreas to diet-induced obesity

(2015) Beatriz Merino et al.   Scientific Reports

Glucagon Couples Hepatic Amino Acid Catabolism to mTOR-Dependent Regulation of α-Cell Mass

(2015) Mark J. Solloway et al.   Cell Reports

Stability of glucagon-like peptide 1 and glucagon in human plasma

(2015) N. J. Wewer Albrechtsen et al.   Endocrine Connections

Absence of Glucagon and Insulin Action Reveals a Role for the GLP-1 Receptor in Endogenous Glucose Production

(2014) Lucy S. Jun et al.   DIABETES

Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

(2014) Nicolai J. Wewer Albrechtsen et al.   DIABETOLOGIA

GLP-1 Receptor Localization in Monkey and Human Tissue: Novel Distribution Revealed With Extensively Validated Monoclonal Antibody

(2014) Charles Pyke et al.   ENDOCRINOLOGY

Targeted Metabolomics of Dried Blood Spot Extracts

(2013) Sven Zukunft et al.   CHROMATOGRAPHIA

Making β Cells from Adult Cells Within the Pancreas

(2013) Philippe A. Lysy et al.   Current Diabetes Reports

Liver-Specific Disruption of the Murine Glucagon Receptor Produces  -Cell Hyperplasia: Evidence for a Circulating  -Cell Growth Factor

(2012) C. Longuet et al.   DIABETES

Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes

(2011) Jianxin Yang et al.   BMC GENOMICS

Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics

(2011) Werner Römisch-Margl et al.   Metabolomics

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Increased hepatic efficacy of urea synthesis from alanine in insulin-dependent diabetes mellitus

(2008) T. P. ALMDAL et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Novel Glucagon Receptor Antagonists with Improved Selectivity over the Glucose-Dependent Insulinotropic Polypeptide Receptor

(2008) János T. Kodra et al.   JOURNAL OF MEDICINAL CHEMISTRY