Acute disruption of glucagon secretion or action does not improve glucose tolerance in an insulin-deficient mouse model of diabetes

Short-term administration of the glucagon receptor antagonist LY2409021 lowers blood glucose in healthy people and in those with type 2 diabetes

(2015) R. P. Kelly et al.   DIABETES OBESITY & METABOLISM

Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway

(2015) May-Yun Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibroblast Growth Factor 21 (FGF21) and Glucagon-Like Peptide 1 Contribute to Diabetes Resistance in Glucagon Receptor-Deficient Mice

(2013) B. A. Omar et al.   DIABETES

Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells

(2012) J Pedersen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Direct effect of GLP-1 infusion on endogenous glucose production in humans

(2012) M. Seghieri et al.   DIABETOLOGIA

Metabolic manifestations of insulin deficiency do not occur without glucagon action

(2012) Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice

(2011) Y. Lee et al.   DIABETES

Normal Glucagon Signaling and β-Cell Function After Near-Total α-Cell Ablation in Adult Mice

(2011) Fabrizio Thorel et al.   DIABETES

Metabolic impact of glucagon deficiency

(2011) Y. Hayashi   DIABETES OBESITY & METABOLISM

Dual elimination of the glucagon and GLP-1 receptors in mice reveals plasticity in the incretin axis

(2011) Safina Ali et al.   JOURNAL OF CLINICAL INVESTIGATION

Novel Glucagon Receptor Antagonists with Improved Selectivity over the Glucose-Dependent Insulinotropic Polypeptide Receptor

(2008) János T. Kodra et al.   JOURNAL OF MEDICINAL CHEMISTRY