Cell confluence regulates claudin-2 expression: possible role for ZO-1 and Rac

Tumor Necrosis Factor-α Increases Claudin-1, 4, and 7 Expression in Tubular Cells: Role in Permeability Changes

(2017) Yasaman Amoozadeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tight junctions of the proximal tubule and their channel proteins

(2017) Michael Fromm et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Claudin-2-mediated cation and water transport share a common pore

(2016) R. Rosenthal et al.   Acta Physiologica

Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells

(2016) Naoko Fujii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paracellular epithelial sodium transport maximizes energy efficiency in the kidney

(2016) Lei Pei et al.   JOURNAL OF CLINICAL INVESTIGATION

Tight junctions: from simple barriers to multifunctional molecular gates

(2016) Ceniz Zihni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms and in vivo functions of contact inhibition of locomotion

(2016) Brian Stramer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Claudins: vital partners in transcellular and paracellular transport coupling

(2016) Dorothee Günzel   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate

(2016) Yiming Wang et al.   PLoS One

Tumor necrosis factor-α induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions

(2015) Yasaman Amoozadeh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Bradykinin increased the permeability of BTB via NOS/NO/ZONAB-mediating down-regulation of claudin-5 and occludin

(2015) Li-bo Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Clathrin-dependent endocytosis of claudin-2 by DFYSP peptide causes lysosomal damage in lung adenocarcinoma A549 cells

(2015) Akira Ikari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Syndecan-1 Acts in Synergy with Tight Junction Through Stat3 Signaling to Maintain Intestinal Mucosal Barrier and Prevent Bacterial Translocation

(2015) Zhongqiu Wang et al.   INFLAMMATORY BOWEL DISEASES

PKCι interacts with Rab14 and modulates epithelial barrier function through regulation of claudin-2 levels

(2015) Ruifeng Lu et al.   MOLECULAR BIOLOGY OF THE CELL

Claudin-2 Knockout by TALEN-Mediated Gene Targeting in MDCK Cells: Claudin-2 Independently Determines the Leaky Property of Tight Junctions in MDCK Cells

(2015) Shinsaku Tokuda et al.   PLoS One

Claudin switching: Physiological plasticity of the Tight Junction

(2015) Christopher T. Capaldo et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Claudins and cancer: Fall of the soldiers entrusted to protect the gate and keep the barrier intact

(2015) Amar B. Singh et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Nuclear distribution of claudin-2 increases cell proliferation in human lung adenocarcinoma cells

(2014) Akira Ikari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Rho protein GTPases and their interactions with NFκB: crossroads of inflammation and matrix biology

(2014) Louis Tong et al.   BIOSCIENCE REPORTS

EGF Regulates Claudin-2 and -4 Expression Through Src and STAT3 in MDCK Cells

(2014) Vicky García-Hernández et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins

(2014) Christopher T. Capaldo et al.   MOLECULAR BIOLOGY OF THE CELL

Impedance analysis of GPCR-mediated changes in endothelial barrier function: overview and fundamental considerations for stable and reproducible measurements

(2014) Judith A. Stolwijk et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Regulation of membrane-type 1 matrix metalloproteinase expression by zonula occludens-2 in human lung cancer cells

(2013) E. Luczka et al.   CLINICAL & EXPERIMENTAL METASTASIS

Emerging Roles of Claudins in Human Cancer

(2013) Mi Kwon   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epithelial barrier assembly requires coordinated activity of multiple domains of the tight junction protein ZO-1

(2013) L. S. Rodgers et al.   JOURNAL OF CELL SCIENCE

Central role of the exchange factor GEF-H1 in TNF-α–induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells

(2013) Faiza Waheed et al.   MOLECULAR BIOLOGY OF THE CELL

The Junctional Proteins Cingulin and Paracingulin Modulate the Expression of Tight Junction Protein Genes through GATA-4

(2013) Laurent Guillemot et al.   PLoS One

SUMOylation of claudin-2

(2012) Christina M. Van Itallie et al.   Annals of the New York Academy of Sciences

Tight junctions on the move: molecular mechanisms for epithelial barrier regulation

(2012) Le Shen   Annals of the New York Academy of Sciences

Loss of Claudins 2 and 15 From Mice Causes Defects in Paracellular Na+ Flow and Nutrient Transport in Gut and Leads to Death from Malnutrition

(2012) Masami Wada et al.   GASTROENTEROLOGY

Phosphorylation of claudin-2 on serine 208 promotes membrane retention and reduces trafficking to lysosomes

(2012) C. M. Van Itallie et al.   JOURNAL OF CELL SCIENCE

Claudin-1 induces epithelial–mesenchymal transition through activation of the c-Abl-ERK signaling pathway in human liver cells

(2012) Y Suh et al.   ONCOGENE

The PIKfyve Inhibitor YM201636 Blocks the Continuous Recycling of the Tight Junction Proteins Claudin-1 and Claudin-2 in MDCK cells

(2012) Joseph D. Dukes et al.   PLoS One

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates

(2012) Faiza Waheed et al.   Jove-Journal of Visualized Experiments

RhoA and Rho kinase mediate cyclosporine A and sirolimus-induced barrier tightening in renal proximal tubular cells

(2011) Natalia Martin-Martin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

β-Catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial–myofibroblast transition

(2011) Emmanuel Charbonney et al.   MOLECULAR BIOLOGY OF THE CELL

The Claudin family and its role in cancer and metastasis

(2010) Astrid Escudero-Esparza   Frontiers in Bioscience-Landmark

The Dual Role of Zonula Occludens (ZO) Proteins

(2010) H. Bauer et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling

(2010) Maren Amasheh et al.   JOURNAL OF CELL SCIENCE

Epidermal growth factor increases clathrin-dependent endocytosis and degradation of claudin-2 protein in MDCK II cells

(2010) Akira Ikari et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Decrease in claudin-2 expression enhances cell migration in renal epithelial madin-darby canine kidney cells

(2010) Akira Ikari et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ZONAB Promotes Proliferation and Represses Differentiation of Proximal Tubule Epithelial Cells

(2010) W. R. Lima et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Rho Signaling and Tight Junction Functions

(2010) Steve Terry et al.   PHYSIOLOGY

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

(2010) M. Buchert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth

(2010) B. W. Murray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Claudin-2–deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules

(2010) Shigeaki Muto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial Tight Junctions in Intestinal Inflammation

(2009) Joerg D. Schulzke et al.   Annals of the New York Academy of Sciences

Novel high-throughput screening system for identifying STAT3–SH2 antagonists

(2009) Yutaka Uehara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activated Rac1 requires gp130 for Stat3 activation, cell proliferation and migration

(2009) Rozanne Arulanandam et al.   EXPERIMENTAL CELL RESEARCH

ZO-1 Stabilizes the Tight Junction Solute Barrier through Coupling to the Perijunctional Cytoskeleton

(2009) Christina M. Van Itallie et al.   MOLECULAR BIOLOGY OF THE CELL

Physiology and Function of the Tight Junction

(2009) J. M. Anderson et al.   Cold Spring Harbor Perspectives in Biology

cAMP induced Rac 1-mediated cytoskeletal reorganization in microvascular endothelium

(2008) Y. Baumer et al.   HISTOCHEMISTRY AND CELL BIOLOGY