NHR-49/HNF4 integrates regulation of fatty acid metabolism with a protective transcriptional response to oxidative stress and fasting

Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans

(2017) Christopher F. Bennett et al.   PLoS Genetics

Caenorhabditis elegans as a model for understanding ROS function in physiology and disease

(2017) Antonio Miranda-Vizuete et al.   Redox Biology

Roles for ROS and hydrogen sulfide in the longevity response to germline loss inCaenorhabditis elegans

(2016) Yuehua Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxic control of metastasis

(2016) E. B. Rankin et al.   SCIENCE

Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals

(2016) Shuhei Nakamura et al.   Nature Communications

The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK

(2016) Cheng-Wei Wu et al.   PLoS Genetics

TAF-4 is required for the life extension of isp-1, clk-1 and tpk-1 Mit mutants

(2016) Maruf H. Khan et al.   Aging-US

Gain-of-Function Alleles in Caenorhabditis elegans Nuclear Hormone Receptor nhr-49 Are Functionally Distinct

(2016) Kayoung Lee et al.   PLoS One

Autophagy-mediated longevity is modulated by lipoprotein biogenesis

(2015) Nicole E. Seah et al.   Autophagy

Stress-mediated translational control in cancer cells

(2015) Gabriel Leprivier et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal

(2015) Kristopher Burkewitz et al.   CELL

SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans

(2015) T. Keith Blackwell et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span

(2015) S. F. Leiser et al.   SCIENCE

Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans

(2015) A. Folick et al.   SCIENCE

Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence

(2015) Michael J Steinbaugh et al.   eLife

A novel kinase regulates dietary restriction-mediated longevity inCaenorhabditis elegans

(2014) Manish Chamoli et al.   AGING CELL

Germline Signals Deploy NHR-49 to Modulate Fatty-Acid β-Oxidation and Desaturation in Somatic Tissues of C. elegans

(2014) Ramesh Ratnappan et al.   PLoS Genetics

The conserved Mediator subunit MDT-15 is required for oxidative stress responses inCaenorhabditis elegans

(2013) Grace Y. S. Goh et al.   AGING CELL

MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability

(2013) Eyleen J. O’Rourke et al.   NATURE CELL BIOLOGY

Targeting the unfolded protein response in disease

(2013) Claudio Hetz et al.   NATURE REVIEWS DRUG DISCOVERY

A cytoprotective perspective on longevity regulation

(2013) David E. Shore et al.   TRENDS IN CELL BIOLOGY

The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans

(2013) Louis R. Lapierre et al.   Nature Communications

A Fasting-Responsive Signaling Pathway that Extends Life Span in C. elegans

(2013) Masaharu Uno et al.   Cell Reports

Dietary Restriction Induced Longevity Is Mediated by Nuclear Receptor NHR-62 in Caenorhabditis elegans

(2013) Bree N. Heestand et al.   PLoS Genetics

Coordinate Regulation of Lipid Metabolism by Novel Nuclear Receptor Partnerships

(2012) Pranali P. Pathare et al.   PLoS Genetics

Life Span Extension via eIF4G Inhibition Is Mediated by Posttranscriptional Remodeling of Stress Response Gene Expression in C. elegans

(2011) Aric N. Rogers et al.   Cell Metabolism

Taking a “good” look at free radicals in the aging process

(2011) Siegfried Hekimi et al.   TRENDS IN CELL BIOLOGY

Hypoxia signaling and resistance in C. elegans

(2010) Jo Anne Powell-Coffman   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Condition-adapted stress and longevity gene regulation byCaenorhabditis elegansSKN-1/Nrf

(2009) Riva P. Oliveira et al.   AGING CELL

Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways inC. elegans

(2009) Eric L. Greer et al.   AGING CELL

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans

(2008) Jennifer M.A. Tullet et al.   CELL

PhosphoPep—a database of protein phosphorylation sites in model organisms

(2008) Bernd Bodenmiller et al.   NATURE BIOTECHNOLOGY

A redox-sensitive peroxiredoxin that is important for longevity has tissue- and stress-specific roles in stress resistance

(2008) M. Olahova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A TRPV Channel Modulates C. elegans Neurosecretion, Larval Starvation Survival, and Adult Lifespan

(2008) Brian H. Lee et al.   PLoS Genetics

The Mediator Subunit MDT-15 Confers Metabolic Adaptation to Ingested Material

(2008) Stefan Taubert et al.   PLoS Genetics