The conserved Mediator subunit MDT-15 is required for oxidative stress responses inCaenorhabditis elegans

Direct and Indirect Gene Regulation by a Life-Extending FOXO Protein in C. elegans: Roles for GATA Factors and Lipid Gene Regulators

(2013) Peichuan Zhang et al.   Cell Metabolism

ROS in AgingCaenorhabditis elegans: Damage or Signaling?

(2012) Patricia Back et al.   Oxidative Medicine and Cellular Longevity

Coordinate Regulation of Lipid Metabolism by Novel Nuclear Receptor Partnerships

(2012) Pranali P. Pathare et al.   PLoS Genetics

Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways

(2012) David E. Shore et al.   PLoS Genetics

Function and Regulation of Lipid Biology in Caenorhabditis elegans Aging

(2012) Nicole Shangming Hou et al.   Frontiers in Physiology

New genes that extend Caenorhabditis elegans’ lifespan in response to reproductive signals

(2011) Mark McCormick et al.   AGING CELL

Redox Control of the Survival of Healthy and Diseased Cells

(2011) Yuxing Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Life Span Extension via eIF4G Inhibition Is Mediated by Posttranscriptional Remodeling of Stress Response Gene Expression in C. elegans

(2011) Aric N. Rogers et al.   Cell Metabolism

Function and regulation of the Mediator complex

(2011) Ronald C Conaway et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Taking a “good” look at free radicals in the aging process

(2011) Siegfried Hekimi et al.   TRENDS IN CELL BIOLOGY

Mechanism of Mediator Recruitment by Tandem Gcn4 Activation Domains and Three Gal11 Activator-Binding Domains

(2010) E. Herbig et al.   MOLECULAR AND CELLULAR BIOLOGY

Nuclear hormone receptors in nematodes: Evolution and function

(2010) Stefan Taubert et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation

(2010) Sohail Malik et al.   NATURE REVIEWS GENETICS

The Role of Nuclear Receptor NHR-64 in Fat Storage Regulation in Caenorhabditis elegans

(2010) Bin Liang et al.   PLoS One

RNAi Screening Implicates a SKN-1–Dependent Transcriptional Response in Stress Resistance and Longevity Deriving from Translation Inhibition

(2010) Jinling Wang et al.   PLoS Genetics

Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1

(2009) Sang-Kyu Park et al.   AGING CELL

Condition-adapted stress and longevity gene regulation byCaenorhabditis elegansSKN-1/Nrf

(2009) Riva P. Oliveira et al.   AGING CELL

Fatty-acid metabolism is involved in stress-resistance mechanisms of Caenorhabditis elegans

(2009) Makoto Horikawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nuclear receptor-like transcription factors in fungi

(2009) A. M. Naar et al.   GENES & DEVELOPMENT

Activator Gcn4 Employs Multiple Segments of Med15/Gal11, Including the KIX Domain, to Recruit Mediator to Target Genesin Vivo

(2009) Iness Jedidi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone

(2009) Aaron J. Przybysz et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The WD40 Repeat Protein WDR-23 Functions with the CUL4/DDB1 Ubiquitin Ligase To Regulate Nuclear Abundance and Activity of SKN-1 in Caenorhabditis elegans

(2009) K. P. Choe et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptional responses to oxidative stress: Pathological and toxicological implications

(2009) Qiang Ma   PHARMACOLOGY & THERAPEUTICS

Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans

(2008) Jennifer M.A. Tullet et al.   CELL

C. elegans dauer formation and the molecular basis of plasticity

(2008) N. Fielenbach et al.   GENES & DEVELOPMENT

Mediator Subunit Gal11p/MED15 Is Required for Fatty Acid-dependent Gene Activation by Yeast Transcription Factor Oaf1p

(2008) Jitendra K. Thakur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A nuclear receptor-like pathway regulating multidrug resistance in fungi

(2008) Jitendra K. Thakur et al.   NATURE

The Mediator Subunit MDT-15 Confers Metabolic Adaptation to Ingested Material

(2008) Stefan Taubert et al.   PLoS Genetics