Cell-specific resetting of mouse islet cellular clocks by glucagon, glucagon-like peptide 1 and somatostatin

Glucose Homeostasis: Regulation by Peripheral Circadian Clocks in Rodents and Humans

(2017) Frédéric Gachon et al.   ENDOCRINOLOGY

Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression

(2017) Volodymyr Petrenko et al.   GENES & DEVELOPMENT

High-Resolution Recording of the Circadian Oscillator in Primary Mouse α- and β-Cell Culture

(2017) Volodymyr Petrenko et al.   Frontiers in Endocrinology

A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells

(2016) C. Saini et al.   DIABETES OBESITY & METABOLISM

Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

(2016) Alice E. Adriaenssens et al.   DIABETOLOGIA

Circadian Transcription from Beta Cell Function to Diabetes Pathophysiology

(2016) Mark Perelis et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets

(2016) Michael R. DiGruccio et al.   Molecular Metabolism

Somatostatin and insulin mediate glucose-inhibited glucagon secretion in the pancreatic α-cell by lowering cAMP

(2015) Amicia D. Elliott et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Circadian timing of metabolism in animal models and humans

(2015) C. Dibner et al.   JOURNAL OF INTERNAL MEDICINE

Pancreatic   cell enhancers regulate rhythmic transcription of genes controlling insulin secretion

(2015) M. Perelis et al.   SCIENCE

Oxyntomodulin regulates resetting of the liver circadian clock by food

(2015) Dominic Landgraf et al.   eLife

The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression

(2014) Christopher Benner et al.   BMC GENOMICS

The Role of β Cell Glucagon-like Peptide-1 Signaling in Glucose Regulation and Response to Diabetes Drugs

(2014) Eric P. Smith et al.   Cell Metabolism

Insulin-FOXO3 Signaling Modulates Circadian Rhythms via Regulation of Clock Transcription

(2014) Inês Chaves et al.   CURRENT BIOLOGY

Circadian Secretion of the Intestinal Hormone GLP-1 by the Rodent L Cell

(2014) Manuel Gil-Lozano et al.   DIABETES

Glucagon-CREB/CRTC2 Signaling Cascade Regulates Hepatic BMAL1 Protein

(2014) Xiujie Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Consequences of Exposure to Light at Night on the Pancreatic Islet Circadian Clock and Function in Rats

(2013) J. Qian et al.   DIABETES

Circadian Clock Characteristics Are Altered in Human Thyroid Malignant Nodules

(2013) Tiphaine Mannic et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Autonomous and self-sustained circadian oscillators displayed in human islet cells

(2012) P. Pulimeno et al.   DIABETOLOGIA

Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators

(2012) C. Saini et al.   GENES & DEVELOPMENT

Paracrine Interactions Within Islets of Langerhans

(2012) Duk-Su Koh et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Real-time monitoring in three-dimensional hepatocytes reveals that insulin acts as a synchronizer for liver clock

(2012) Daisuke Yamajuku et al.   Scientific Reports

Glucose- and Hormone-Induced cAMP Oscillations in  - and  -Cells Within Intact Pancreatic Islets

(2011) G. Tian et al.   DIABETES

GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis

(2010) Yang Z. De Marinis et al.   Cell Metabolism

An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice

(2010) L. A. Sadacca et al.   DIABETOLOGIA

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

A software solution for recording circadian oscillator features in time-lapse live cell microscopy

(2010) Daniel Sage et al.   Cell Division

Glucose Generates Coincident Insulin and Somatostatin Pulses and Antisynchronous Glucagon Pulses from Human Pancreatic Islets

(2009) Bo Hellman et al.   ENDOCRINOLOGY

Differential expression of glucagon and glucagon-like peptide 1 receptors in mouse pancreatic alpha and beta cells in two models of alpha cell hyperplasia

(2009) Mamdouh H. Kedees et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression

(2009) Christopher Vollmers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of the GLP-1 Receptor in Mouse, Rat, and Human Pancreas

(2008) Ditte Tornehave et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY