Duhuo Jisheng Decoction inhibits SDF-1-induced inflammation and matrix degradation in human degenerative nucleus pulposus cells in vitro through the CXCR4/NF-κB pathway

Protective Effect of Gentianine, a compound from Du Huo Ji Sheng Tang, against Freund’s Complete Adjuvant-Induced Arthritis in Rats

(2017) Chen Wenjin et al.   INFLAMMATION

Du-Huo-Ji-Sheng-Tang and its active component Ligusticum chuanxiong promote osteogenic differentiation and decrease the aging process of human mesenchymal stem cells

(2017) Jir-You Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of Angelicae Pubescentis and Loranthi Decotion on repairing knee joint cartilages in rats

(2017) Shun Lyu et al.   Journal of Orthopaedic Surgery and Research

Iridoid–loganic acid versus anthocyanins from the Cornus mas fruits (cornelian cherry): Common and different effects on diet-induced atherosclerosis, PPARs expression and inflammation

(2016) Tomasz Sozański et al.   ATHEROSCLEROSIS

SDF-1/CXCR4 axis induces apoptosis of human degenerative nucleus pulposus cells via the NF-κB pathway

(2016) ZONGCHAO LIU et al.   Molecular Medicine Reports

Evidence of Chinese herbal medicine Duhuo Jisheng decoction for knee osteoarthritis: a systematic review of randomised clinical trials

(2016) Wenming Zhang et al.   BMJ Open

Fangjiomics: revealing adaptive omics pharmacological mechanisms of the myriad combination therapies to achieve personalized medicine

(2015) Dayue Darrel Duan et al.   ACTA PHARMACOLOGICA SINICA

Editorial (Thematic Issue): Combination Therapy of Vascular Diseases and Fangjiomics: When West Meets East in the Era of Phenomics

(2015) Zhong Wang et al.   Current Vascular Pharmacology

Osthole inhibits inflammatory cytokine release through PPARα/γ-mediated mechanisms in LPS-stimulated 3T3-L1 adipocytes

(2015) Xiao-li Wang et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Duhuo Jisheng decoction inhibits endoplasmic reticulum stress in chondrocytes induced by tunicamycin through the downregulation of miR-34a

(2015) FAYUAN LIU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Autophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells, as sustained by NF-κB and JNK inhibition

(2015) KANG XU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Osthole Attenuates Inflammatory Responses and Regulates the Expression of Inflammatory Mediators in HepG2 Cells Grown in Differentiated Medium from 3T3-L1 Preadipocytes

(2015) Shu-Ju Wu   JOURNAL OF MEDICINAL FOOD

Effects of Nuclear Factor Kappa B Signaling Pathway in Human Intervertebral Disc Degeneration

(2015) Sun Zhongyi et al.   SPINE

The Changes in the Expression of NF-KB in a Degenerative Human Intervertebral Disc model

(2014) Zhongyi Sun et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Stromal Cell-derived Factor-1 and its Receptor CXCR4 are Upregulated Expression in Degenerated Intervertebral Discs

(2014) Hua Zhang et al.   International Journal of Medical Sciences

Duhuo Jisheng decoction treatment inhibits the sodium nitroprussiate-induced apoptosis of chondrocytes through the mitochondrial-dependent signaling pathway

(2014) FAYUAN LIU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

NF-κB-inducing kinase is a key regulator of inflammation-induced and tumour-associated angiogenesis

(2014) Ae R Noort et al.   JOURNAL OF PATHOLOGY

Total Glucosides of Paeony Attenuate Renal Tubulointerstitial Injury in STZ-Induced Diabetic Rats: Role of Toll-Like Receptor 2

(2014) Wei Zhang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Duhuo Jisheng Decoction-containing serum promotes proliferation of interleukin-1β-induced chondrocytes through the p16-cyclin D1/CDK4-Rb pathway

(2014) GUANGWEN WU et al.   Molecular Medicine Reports

The protective effect of the Cornus mas fruits (cornelian cherry) on hypertriglyceridemia and atherosclerosis through PPARα activation in hypercholesterolemic rabbits

(2014) T. Sozański et al.   PHYTOMEDICINE

The Importance of the Prenyl Group in the Activities of Osthole in Enhancing Bone Formation and Inhibiting Bone ResorptionIn Vitro

(2014) Yuan-Kun Zhai et al.   International Journal of Endocrinology

Duhuo Jisheng Decoction promotes chondrocyte proliferation through accelerated G1/S transition in osteoarthritis

(2013) GUANGWEN WU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Computational approaches for exploring the potential synergy and polypharmacology of Duhuo Jisheng Decoction in the therapy of osteoarthritis

(2013) CHUN-SONG ZHENG et al.   Molecular Medicine Reports

Role of cytokines in intervertebral disc degeneration: pain and disc content

(2013) Makarand V. Risbud et al.   Nature Reviews Rheumatology

An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes

(2013) Dessislava Z Markova et al.   ARTHRITIS RESEARCH & THERAPY

Reciprocal Activation of CD4+ T Cells and Synovial Fibroblasts by Stromal Cell-Derived Factor 1 Promotes RANKL Expression and Osteoclastogenesis in Rheumatoid Arthritis

(2013) Hae-Rim Kim et al.   Arthritis & Rheumatology

Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis

(2012) Wei Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Expert Consensus on the Treatment of Rheumatoid Arthritis with Chinese Patent Medicines

(2012) Jing Zhao et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

TNF-α and IL-1β Promote a Disintegrin-like and Metalloprotease with Thrombospondin Type I Motif-5-mediated Aggrecan Degradation through Syndecan-4 in Intervertebral Disc

(2011) Jianru Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osthole stimulates osteoblast differentiation and bone formation by activation of β-catenin-BMP signaling

(2010) De-Zhi Tang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Is Duhuo Jisheng Tang containing Xixin safe? A four-week safety study

(2010) Shu-Ching Hsieh et al.   Chinese Medicine

Preventive effects of Flos Perariae (Gehua) water extract and its active ingredient puerarin in rodent alcoholism models

(2010) Zaijun Zhang et al.   Chinese Medicine

Effects of AIF on Knee Osteoarthritis Patients: Double-blind, Randomized Placebo-controlled Study

(2009) Sung-Hoon Park et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

The anticoagulant ability of ferulic acid and its applications for improving the blood compatibility of silk fibroin

(2008) Song Wang et al.   Biomedical Materials

Bone-derived SDF-1 stimulates IL-6 release via CXCR4, ERK and NF- B pathways and promotes osteoclastogenesis in human oral cancer cells

(2008) C.-H. Tang et al.   CARCINOGENESIS

Down-regulation of NR2B receptors partially contributes to analgesic effects of Gentiopicroside in persistent inflammatory pain

(2008) L CHEN et al.   NEUROPHARMACOLOGY