An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes

Inflammatory Cytokines Associated with Degenerative Disc Disease Control Aggrecanase-1 (ADAMTS-4) Expression in Nucleus Pulposus Cells through MAPK and NF-κB

(2013) Ye Tian et al.   AMERICAN JOURNAL OF PATHOLOGY

Inflammatory Cytokines Induce NOTCH Signaling in Nucleus Pulposus Cells

(2013) Hua Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prolyl Hydroxylase 3 (PHD3) Modulates Catabolic Effects of Tumor Necrosis Factor-α (TNF-α) on Cells of the Nucleus Pulposus through Co-activation of Nuclear Factor κB (NF-κB)/p65 Signaling

(2012) Nobuyuki Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Homing of Mesenchymal Stem Cells in Induced Degenerative Intervertebral Discs in a Whole Organ Culture System

(2012) Svenja Illien-Jünger et al.   SPINE

Development of an intact intervertebral disc organ culture system in which degeneration can be induced as a prelude to studying repair potential

(2011) Bernice Jim et al.   EUROPEAN SPINE JOURNAL

Variations in aggrecan localization and gene expression patterns characterize increasing stages of human intervertebral disk degeneration

(2011) Helen E. Gruber et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

TNF-α and IL-1β Promote a Disintegrin-like and Metalloprotease with Thrombospondin Type I Motif-5-mediated Aggrecan Degradation through Syndecan-4 in Intervertebral Disc

(2011) Jianru Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Time course investigation of intervertebral disc degeneration produced by needle-stab injury of the rat caudal spine

(2011) Huina Zhang et al.   JOURNAL OF NEUROSURGERY-SPINE

Mechanical Deformation and Glycosaminoglycan Content Changes in a Rabbit Annular Puncture Disc Degeneration Model

(2011) Deva D. Chan et al.   SPINE

Does Lumbar Disc Degeneration on Magnetic Resonance Imaging Associate With Low Back Symptom Severity in Young Finnish Adults?

(2011) Jani Takatalo et al.   SPINE

An organ culture system to model early degenerative changes of the intervertebral disc

(2011) Ravi K Ponnappan et al.   ARTHRITIS RESEARCH & THERAPY

Accelerated aging of intervertebral discs in a mouse model of progeria

(2010) Nam Vo et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Behavioral Signs of Chronic Back Pain in the SPARC-Null Mouse

(2010) IMagali Millecamps et al.   SPINE

Human Nucleus Pulposus Cells React to IL-6

(2010) Rebecca K. Studer et al.   SPINE

Modified expression of the ADAMTS enzymes and tissue inhibitor of metalloproteinases 3 during human intervertebral disc degeneration

(2009) Aneta J. Pockert et al.   ARTHRITIS AND RHEUMATISM

Intervertebral disc regeneration in an ex vivo culture system using mesenchymal stem cells and platelet-rich plasma

(2009) Wei-Hong Chen et al.   BIOMATERIALS

CCL20 produced in the cytokine network of rheumatoid arthritis recruits CCR6+ mononuclear cells and enhances the production of IL-6

(2009) Shimei Tanida et al.   CYTOKINE

Gene expression profiles of disc tissues and peripheral blood mononuclear cells from patients with degenerative discs

(2009) Yin-gang Zhang et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Proinflammatory Cytokines Synergistically Enhance the Production of Chemokine Ligand 20 (CCL20) from Rheumatoid Fibroblast-like Synovial Cells in vitro and Serum CCL20 Is Reduced in vivo by Biologic Disease-modifying Antirheumatic Drugs

(2009) S.-Y. KAWASHIRI et al.   JOURNAL OF RHEUMATOLOGY

Needle Puncture Injury Affects Intervertebral Disc Mechanics and Biology in an Organ Culture Model

(2009) Casey L. Korecki et al.   SPINE

A Continuous Observation of the Degenerative Process in the Intervertebral Disc of Smad3 Gene Knock-Out Mice

(2009) Chen-Guang Li et al.   SPINE

Therapeutic effects of adenovirus-mediated growth and differentiation factor-5 in a mice disc degeneration model induced by annulus needle puncture

(2009) Haixiang Liang et al.   Spine Journal

Reversine Enhances Generation of Progenitor-like Cells by Dedifferentiation of Annulus Fibrosus Cells

(2009) Mansi Saraiya et al.   TISSUE ENGINEERING PART A

Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc

(2009) Helen E Gruber et al.   ARTHRITIS RESEARCH & THERAPY

Association of the Asporin D14 Allele with Lumbar-Disc Degeneration in Asians

(2008) You-Qiang Song et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Bovine explant model of degeneration of the intervertebral disc

(2008) Sally Roberts et al.   BMC MUSCULOSKELETAL DISORDERS

Heterozygous disruption of Flk-1 receptor leads to myocardial ischaemia reperfusion injury in mice: application of affymetrix gene chip analysis

(2008) M. Thirunavukkarasu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE