Reciprocal Activation of CD4+ T Cells and Synovial Fibroblasts by Stromal Cell-Derived Factor 1 Promotes RANKL Expression and Osteoclastogenesis in Rheumatoid Arthritis

Regulation of osteoclast function

(2014) Ichiro Nakamura et al.   Modern Rheumatology

Novel small-molecular therapeutics for rheumatoid arthritis

(2012) Roy Fleischmann   CURRENT OPINION IN RHEUMATOLOGY

Rituximab abrogates joint destruction in rheumatoid arthritis by inhibiting osteoclastogenesis

(2011) Maria J H Boumans et al.   ANNALS OF THE RHEUMATIC DISEASES

Pathogenesis of Joint Destruction in Rheumatoid Arthritis

(2011) Shunichi Shiozawa et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone

(2011) Joel M. Kremer et al.   ARTHRITIS AND RHEUMATISM

DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts

(2011) E Karouzakis et al.   GENES AND IMMUNITY

Why TNF-α inhibition is not sufficient to avoid juxta-articular erosions in chronic arthritis?

(2011) Nicola Maruotti et al.   Internal and Emergency Medicine

Stromal cell-derived factor-1/CXCR4 promotes IL-6 production in human synovial fibroblasts

(2011) Hsien-Te Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Osteoclastogenesis and arthritis

(2010) Nicola Maruotti et al.   CLINICAL AND EXPERIMENTAL MEDICINE

CXCL12 gene expression is upregulated by hypoxia and growth arrest but not by inflammatory cytokines in rheumatoid synovial fibroblasts

(2010) Begoña Santiago et al.   CYTOKINE

An Oral Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid Arthritis

(2010) Michael E. Weinblatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bone Damage in Rheumatoid Arthritis: Mechanistic Insights and Approaches to Prevention

(2010) Sougata Karmakar et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Erosive progression is minimal, but erosion healing rare, in patients with rheumatoid arthritis treated with adalimumab. A 1 year investigator-initiated follow-up study using high-resolution computed tomography as the primary outcome measure

(2008) U M. Dohn et al.   ANNALS OF THE RHEUMATIC DISEASES

Adalimumab therapy reduces hand bone loss in early rheumatoid arthritis: explorative analyses from the PREMIER study

(2008) M Hoff et al.   ANNALS OF THE RHEUMATIC DISEASES

Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: Fibroblast-mediated pathologic bone resorption

(2008) Miklos Tunyogi-Csapo et al.   ARTHRITIS AND RHEUMATISM

Bone-derived SDF-1 stimulates IL-6 release via CXCR4, ERK and NF- B pathways and promotes osteoclastogenesis in human oral cancer cells

(2008) C.-H. Tang et al.   CARCINOGENESIS

Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients

(2008) Takuji Iwamoto et al.   FEBS Journal

TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood

(2008) Qian Zhang et al.   ARTHRITIS RESEARCH & THERAPY