Interplay among gut microbiota, intestinal mucosal barrier and enteric neuro-immune system: a common path to neurodegenerative diseases?

Unique expression pattern of KIBRA in the enteric nervous system of APP/PS1 mice

(2018) Jianli Feng et al.   NEUROSCIENCE LETTERS

Alzheimer’s disease and gut microbiota modifications: The long way between preclinical studies and clinical evidence

(2018) Cesare Mancuso et al.   PHARMACOLOGICAL RESEARCH

Longitudinal Analysis of Fecal Microbiome and Pathologic Processes in a Rotenone Induced Mice Model of Parkinson’s Disease

(2018) Xiaodong Yang et al.   Frontiers in Aging Neuroscience

Changes of the Enteric Nervous System in Amyloid-β Protein Precursor Transgenic Mice Correlate with Disease Progression

(2018) Sandra Semar et al.   JOURNAL OF ALZHEIMERS DISEASE

The gut-brain axis in Parkinson's disease: Possibilities for food-based therapies

(2017) Paula Perez-Pardo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Alzheimer’s Disease Histological and Behavioral Manifestations in Transgenic Mice Correlate with Specific Gut Microbiome State

(2017) Liang Shen et al.   JOURNAL OF ALZHEIMERS DISEASE

The Gut Microbiota and Alzheimer’s Disease

(2017) Chunmei Jiang et al.   JOURNAL OF ALZHEIMERS DISEASE

Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer’s Mouse Model

(2017) Carolin Brandscheid et al.   JOURNAL OF ALZHEIMERS DISEASE

The prodromal microbiome

(2017) Filip Scheperjans   MOVEMENT DISORDERS

Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome

(2017) Erin M. Hill-Burns et al.   MOVEMENT DISORDERS

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

Loss of nitrergic and cholinergic neurons in the enteric nervous system of APP/PS1 transgenic mouse model

(2017) Xiaolei Han et al.   NEUROSCIENCE LETTERS

Diet, Gut Microbiota, and Vitamins D + A in Multiple Sclerosis

(2017) Paolo Riccio et al.   Neurotherapeutics

Progression of Parkinson's disease is associated with gut dysbiosis: Two-year follow-up study

(2017) Tomomi Minato et al.   PLoS One

Gut Microbiota: A Potential Regulator of Neurodevelopment

(2017) Paola Tognini   Frontiers in Cellular Neuroscience

Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson’s disease patients

(2017) J. R. Bedarf et al.   Genome Medicine

Interactions between Intestinal Microbiota and Host Immune Response in Inflammatory Bowel Disease

(2017) Ming Zhang et al.   Frontiers in Immunology

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

(2017) T. Harach et al.   Scientific Reports

Microbiota modulation counteracts Alzheimer’s disease progression influencing neuronal proteolysis and gut hormones plasma levels

(2017) Laura Bonfili et al.   Scientific Reports

Gut microbiome alterations in Alzheimer’s disease

(2017) Nicholas M. Vogt et al.   Scientific Reports

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

The Intestinal Immune System in Obesity and Insulin Resistance

(2016) Daniel A. Winer et al.   Cell Metabolism

The Effect of Microbiota and the Immune System on the Development and Organization of the Enteric Nervous System

(2016) Yuuki Obata et al.   GASTROENTEROLOGY

Growing up in a Bubble: Using Germ-Free Animals to Assess the Influence of the Gut Microbiota on Brain and Behavior

(2016) Pauline Luczynski et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Altered intestinal permeability in patients with relapsing–remitting multiple sclerosis: A pilot study

(2016) Maria Chiara Buscarinu et al.   Multiple Sclerosis Journal

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

The bowel and beyond: the enteric nervous system in neurological disorders

(2016) Meenakshi Rao et al.   Nature Reviews Gastroenterology & Hepatology

Intestinal dysfunction in Parkinson's disease: Lessons learned from translational studies and experimental models

(2016) C. Pellegrini et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Review: Sporadic Parkinson's disease: development and distribution ofα-synuclein pathology

(2016) K. Del Tredici et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease

(2016) Francesca Pistollato et al.   NUTRITION REVIEWS

Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls

(2016) Marcus M. Unger et al.   PARKINSONISM & RELATED DISORDERS

Microbiota-gut-brain signalling in Parkinson's disease: Implications for non-motor symptoms

(2016) Valeria D. Felice et al.   PARKINSONISM & RELATED DISORDERS

Alzheimer’s disease and gut microbiota

(2016) Xu Hu et al.   Science China-Life Sciences

Evaluation of the Microbial Diversity in Amyotrophic Lateral Sclerosis Using High-Throughput Sequencing

(2016) Xin Fang et al.   Frontiers in Microbiology

Aberrations in Peripheral Inflammatory Cytokine Levels in Parkinson Disease

(2016) Xiao-Yan Qin et al.   JAMA Neurology

Altered intestinal permeability in patients with relapsing–remitting multiple sclerosis: A pilot study

(2016) Maria Chiara Buscarinu et al.   Multiple Sclerosis Journal

Gastrointestinal Dysfunctions in Parkinson’s Disease: Symptoms and Treatments

(2016) Andrée-Anne Poirier et al.   Parkinsons Disease

The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new therapeutic directions

(2016) Stephen M. Vindigni et al.   Therapeutic Advances in Gastroenterology

Intestinal Microbiota Is Influenced by Gender and Body Mass Index

(2016) Carmen Haro et al.   PLoS One

Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls

(2016) Jun Chen et al.   Scientific Reports

Evaluation of dysphagia at the initial diagnosis of amyotrophic lateral sclerosis

(2015) Shigeyuki Murono et al.   AURIS NASUS LARYNX

Partial depletion of the proinflammatory monocyte population is neuroprotective in the myenteric plexus but not in the basal ganglia in a MPTP mouse model of Parkinson’s disease

(2015) M. Côté et al.   BRAIN BEHAVIOR AND IMMUNITY

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine

(2015) Aiden Haghikia et al.   IMMUNITY

Gut/brain axis and the microbiota

(2015) Emeran A. Mayer et al.   JOURNAL OF CLINICAL INVESTIGATION

Elevated fecal calprotectin in patients with Alzheimer’s dementia indicates leaky gut

(2015) Friedrich Leblhuber et al.   JOURNAL OF NEURAL TRANSMISSION

Colonic bacterial composition in Parkinson's disease

(2015) Ali Keshavarzian et al.   MOVEMENT DISORDERS

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Microbiota Controls the Homeostasis of Glial Cells in the Gut Lamina Propria

(2015) Panagiotis S. Kabouridis et al.   NEURON

Inflammation is genetically implicated in Parkinson’s disease

(2015) N. Dzamko et al.   NEUROSCIENCE

Gastric motor dysfunctions in Parkinson's disease: Current pre-clinical evidence

(2015) Carolina Pellegrini et al.   PARKINSONISM & RELATED DISORDERS

Structural alterations of the intestinal epithelial barrier in Parkinson’s disease

(2015) Thomas Clairembault et al.   Acta Neuropathologica Communications

Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters

(2015) Sachiko Miyake et al.   PLoS One

Intestinal Dysbiosis and Lowered Serum Lipopolysaccharide-Binding Protein in Parkinson’s Disease

(2015) Satoru Hasegawa et al.   PLoS One

Microglia Development and Function

(2014) Debasis Nayak et al.   Annual Review of Immunology

Intestinal permeability – a new target for disease prevention and therapy

(2014) Stephan C Bischoff et al.   BMC GASTROENTEROLOGY

Enteric Glial Cells: Recent Developments and Future Directions

(2014) Michel Neunlist et al.   GASTROENTEROLOGY

Enteric GFAP expression and phosphorylation in Parkinson's disease

(2014) Thomas Clairembault et al.   JOURNAL OF NEUROCHEMISTRY

Gut microbiota are related to Parkinson's disease and clinical phenotype

(2014) Filip Scheperjans et al.   MOVEMENT DISORDERS

Intestinal Barrier Dysfunction Develops at the Onset of Experimental Autoimmune Encephalomyelitis, and Can Be Induced by Adoptive Transfer of Auto-Reactive T Cells

(2014) Mehrnaz Nouri et al.   PLoS One

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Enteric glial cells and their role in the intestinal epithelial barrier

(2014) Yan-Bo Yu   WORLD JOURNAL OF GASTROENTEROLOGY

Increased prevalence of bladder and intestinal dysfunction in amyotrophic lateral sclerosis

(2014) Georg S. Nübling et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Gut microbiota, enteroendocrine functions and metabolism

(2013) Patrice D Cani et al.   CURRENT OPINION IN PHARMACOLOGY

Toll-Like Receptor 2 Regulates Intestinal Inflammation by Controlling Integrity of the Enteric Nervous System

(2013) Paola Brun et al.   GASTROENTEROLOGY

Gender Bias in Autoimmunity Is Influenced by Microbiota

(2013) Leonid Yurkovetskiy et al.   IMMUNITY

Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease

(2013) Leo P. Kelly et al.   MOVEMENT DISORDERS

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

The prion hypothesis in Parkinson's disease: Braak to the future

(2013) Naomi P Visanji et al.   Acta Neuropathologica Communications

1-Heteroaromatic-Substituted Tetraphenylboroles: π–π Interactions Between Aromatic and Antiaromatic Rings Through a B–C Bond

(2012) Holger Braunschweig et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Is alpha-synuclein in the colon a biomarker for premotor Parkinson's Disease? Evidence from 3 cases

(2012) Kathleen M. Shannon et al.   MOVEMENT DISORDERS

Reciprocal interactions of the intestinal microbiota and immune system

(2012) Craig L. Maynard et al.   NATURE

The enteric nervous system and neurogastroenterology

(2012) John B. Furness   Nature Reviews Gastroenterology & Hepatology

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Colonic inflammation in Parkinson's disease

(2012) David Devos et al.   NEUROBIOLOGY OF DISEASE

The microbiome is essential for normal gut intrinsic primary afferent neuron excitability in the mouse

(2012) K. A. McVey Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The critical role of the MyD88-dependent pathway in non-CNS MPTP-mediated toxicity

(2011) M. Côté et al.   BRAIN BEHAVIOR AND IMMUNITY

Incidence of Serious Upper and Lower Gastrointestinal Events in Older Adults with and without Alzheimer's Disease

(2011) Jasmanda H. Wu et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease

(2011) Christopher B. Forsyth et al.   PLoS One

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbiota-stimulated immune mechanisms to maintain gut homeostasis

(2010) Hachung Chung et al.   CURRENT OPINION IN IMMUNOLOGY

Bacterial infection causes stress-induced memory dysfunction in mice

(2010) M. G. Gareau et al.   GUT

Molecular Modulation of Intestinal Epithelial Barrier: Contribution of Microbiota

(2010) Renu Sharma et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

A Novel Probiotic Mixture Exerts a Therapeutic Effect on Experimental Autoimmune Encephalomyelitis Mediated by IL-10 Producing Regulatory T Cells

(2010) Shahram Lavasani et al.   PLoS One

Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

(2010) Y. K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of gastrointestinal involvement and depressive symptoms in patients with systemic sclerosis

(2010) V. Bodukam et al.   RHEUMATOLOGY

Enteric glial cells protect neurons from oxidative stress in part via reduced glutathione

(2009) Hind Abdo et al.   FASEB JOURNAL

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NKT Cell-Dependent Amelioration of a Mouse Model of Multiple Sclerosis by Altering Gut Flora

(2008) Hiroaki Yokote et al.   AMERICAN JOURNAL OF PATHOLOGY