Implications for Diverse Functions of the LINC Complexes Based on the Structure

Nesprin-2G, a Component of the Nuclear LINC Complex, Is Subject to Myosin-Dependent Tension

(2016) Paul T. Arsenovic et al.   BIOPHYSICAL JOURNAL

An Unresolved LINC in the Nuclear Envelope

(2016) Mehdi Torbati et al.   Cellular and Molecular Bioengineering

LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining

(2016) Katherine S. Lawrence et al.   JOURNAL OF CELL BIOLOGY

Nuclear migration events throughout development

(2016) Courtney R. Bone et al.   JOURNAL OF CELL SCIENCE

Coiled-Coil Domains of SUN Proteins as Intrinsic Dynamic Regulators

(2016) Si Nie et al.   STRUCTURE

SUN1 splice variants, SUN1_888, SUN1_785, and predominant SUN1_916, variably function in directional cell migration

(2016) Yu Nishioka et al.   Nucleus

SUN1 splice variants, SUN1_888, SUN1_785, and predominant SUN1_916, variably function in directional cell migration

(2016) Yu Nishioka et al.   Nucleus

A Disulfide Bond Is Required for the Transmission of Forces through SUN-KASH Complexes

(2015) Zeinab Jahed et al.   BIOPHYSICAL JOURNAL

Sun1 deficiency leads to cerebellar ataxia in mice

(2015) J.-Y. Wang et al.   Disease Models & Mechanisms

Nuclear–cytoskeletal linkages facilitate cross talk between the nucleus and intercellular adhesions

(2015) Rachel M. Stewart et al.   JOURNAL OF CELL BIOLOGY

Mechanism and Regulation of Rapid Telomere Prophase Movements in Mouse Meiotic Chromosomes

(2015) Chih-Ying Lee et al.   Cell Reports

Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts

(2015) Wakam Chang et al.   Nucleus

Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts

(2015) Wakam Chang et al.   Nucleus

KASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus

(2014) GW Gant Luxton et al.   CURRENT OPINION IN CELL BIOLOGY

SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown

(2014) Yagmur Turgay et al.   JOURNAL OF CELL BIOLOGY

The SUN protein UNC-84 is required only in force-bearing cells to maintain nuclear envelope architecture

(2014) Natalie E. Cain et al.   JOURNAL OF CELL BIOLOGY

Dysregulated interactions between lamin A and SUN1 induce abnormalities in the nuclear envelope and endoplasmic reticulum in progeric laminopathies

(2014) Z.-J. Chen et al.   JOURNAL OF CELL SCIENCE

Nuclear Lamins and Neurobiology

(2014) S. G. Young et al.   MOLECULAR AND CELLULAR BIOLOGY

The TRF1-binding protein TERB1 promotes chromosome movement and telomere rigidity in meiosis

(2014) Hiroki Shibuya et al.   NATURE CELL BIOLOGY

Mitotic phosphorylation of SUN1 loosens its connection with the nuclear lamina while the LINC complex remains intact

(2014) Jennifer T Patel et al.   Nucleus

Nuclear Positioning

(2013) Gregg G. Gundersen et al.   CELL

Nesprins: from the nuclear envelope and beyond

(2013) Dipen Rajgor et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling

(2013) Monika Zwerger et al.   HUMAN MOLECULAR GENETICS

A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton

(2013) Henning F. Horn et al.   JOURNAL OF CELL BIOLOGY

Matefin/SUN-1 Phosphorylation Is Part of a Surveillance Mechanism to Coordinate Chromosome Synapsis and Recombination with Meiotic Progression and Chromosome Movement

(2013) Alexander Woglar et al.   PLoS Genetics

LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins

(2012) Brian A. Sosa et al.   CELL

Structural insights into SUN-KASH complexes across the nuclear envelope

(2012) Wenjia Wang et al.   CELL RESEARCH

Localized Products of futile cycle/ lrmp Promote Centrosome-Nucleus Attachment in the Zebrafish Zygote

(2012) Robin E. Lindeman et al.   CURRENT BIOLOGY

Inner Nuclear Envelope Proteins SUN1 and SUN2 Play a Prominent Role in the DNA Damage Response

(2012) Kai Lei et al.   CURRENT BIOLOGY

Connecting the nucleus to the cytoskeleton by SUN–KASH bridges across the nuclear envelope

(2012) Erin C Tapley et al.   CURRENT OPINION IN CELL BIOLOGY

Altered chromatin organization and SUN2 localization in mandibuloacral dysplasia are rescued by drug treatment

(2012) Daria Camozzi et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Dynein-dependent processive chromosome motions promote homologous pairing inC. elegansmeiosis

(2012) David J. Wynne et al.   JOURNAL OF CELL BIOLOGY

Acetylation of the SUN protein Mps3 by Eco1 regulates its function in nuclear organization

(2012) Suman Ghosh et al.   MOLECULAR BIOLOGY OF THE CELL

The nuclear lamins: flexibility in function

(2012) Brian Burke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The nuclear envelope proteome differs notably between tissues

(2012) Nadia Korfali et al.   Nucleus

SPAG4L, a Novel Nuclear Envelope Protein Involved in the Meiotic Stage of Spermatogenesis

(2011) Xian-Zhen Jiang et al.   DNA AND CELL BIOLOGY

Structure of Sad1-UNC84 Homology (SUN) Domain Defines Features of Molecular Bridge in Nuclear Envelope

(2011) Zhaocai Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TAN lines

(2011) G.W. Gant Luxton et al.   Nucleus

Cell-specific and lamin-dependent targeting of novel transmembrane proteins in the nuclear envelope

(2010) Poonam Malik et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Leukocyte Nuclear Envelope Proteome Varies with Cell Activation and Contains Novel Transmembrane Proteins That Affect Genome Architecture

(2010) Nadia Korfali et al.   MOLECULAR & CELLULAR PROTEOMICS

Several Novel Nuclear Envelope Transmembrane Proteins Identified in Skeletal Muscle Have Cytoskeletal Associations

(2010) Gavin S. Wilkie et al.   MOLECULAR & CELLULAR PROTEOMICS

SPAG4L/SPAG4L-2 are testis-specific SUN domain proteins restricted to the apical nuclear envelope of round spermatids facing the acrosome

(2010) C. Frohnert et al.   MOLECULAR HUMAN REPRODUCTION

Mammalian Sperm Head Formation Involves Different Polarization of Two Novel LINC Complexes

(2010) Eva Göb et al.   PLoS One

Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement

(2010) E. S. Folker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

(2010) G. W. G. Luxton et al.   SCIENCE

Leptotene/Zygotene Chromosome Movement Via the SUN/KASH Protein Bridge in Caenorhabditis elegans

(2010) Antoine Baudrimont et al.   PLoS Genetics

The SUN Rises on Meiotic Chromosome Dynamics

(2009) Yasushi Hiraoka et al.   DEVELOPMENTAL CELL

Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins

(2009) C. Ostlund et al.   JOURNAL OF CELL SCIENCE

SUN1/2 and Syne/Nesprin-1/2 Complexes Connect Centrosome to the Nucleus during Neurogenesis and Neuronal Migration in Mice

(2009) Xiaochang Zhang et al.   NEURON

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

(2009) K. J. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sun1 forms immobile macromolecular assemblies at the nuclear envelope

(2008) Wenshu Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Expression of the myodystrophic R453W mutation of lamin A in C2C12 myoblasts causes promoter-specific and global epigenetic defects

(2008) Anne-Mari Håkelien et al.   EXPERIMENTAL CELL RESEARCH

Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness

(2008) P.J. Stewart-Hutchinson et al.   EXPERIMENTAL CELL RESEARCH

Disruption of nesprin-1 produces an Emery Dreifuss muscular dystrophy-like phenotype in mice

(2008) M. J. Puckelwartz et al.   HUMAN MOLECULAR GENETICS

Dictyostelium Sun-1 Connects the Centrosome to Chromatin and Ensures Genome Stability

(2008) Huajiang Xiong et al.   TRAFFIC