SUN1 splice variants, SUN1_888, SUN1_785, and predominant SUN1_916, variably function in directional cell migration

Nuclear migration events throughout development

(2016) Courtney R. Bone et al.   JOURNAL OF CELL SCIENCE

53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair

(2015) Francisca Lottersberger et al.   CELL

Sun1 deficiency leads to cerebellar ataxia in mice

(2015) J.-Y. Wang et al.   Disease Models & Mechanisms

SUN2 exerts tumor suppressor functions by suppressing the Warburg effect in lung cancer

(2015) Xiao-bin Lv et al.   Scientific Reports

Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts

(2015) Wakam Chang et al.   Nucleus

Global loss of a nuclear lamina component, lamin A/C, and LINC complex components SUN1, SUN2, and nesprin-2 in breast cancer

(2015) Ayaka Matsumoto et al.   Cancer Medicine

Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts

(2015) Wakam Chang et al.   Nucleus

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration

(2014) Samantha J. King et al.   Cytoskeleton

Muscular Dystrophy-Associated SUN1 and SUN2 Variants Disrupt Nuclear-Cytoskeletal Connections and Myonuclear Organization

(2014) Peter Meinke et al.   PLoS Genetics

LINCing lamin B2 to neuronal migration

(2014) Catherine Coffinier et al.   Nucleus

Mitotic phosphorylation of SUN1 loosens its connection with the nuclear lamina while the LINC complex remains intact

(2014) Jennifer T Patel et al.   Nucleus

SUN proteins and nuclear envelope spacing

(2014) Natalie E Cain et al.   Nucleus

Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motilityin vitroand drives tumor formationin vivo

(2013) Yuhki Yokoyama et al.   CANCER SCIENCE

Nuclear Positioning

(2013) Gregg G. Gundersen et al.   CELL

Nesprins: from the nuclear envelope and beyond

(2013) Dipen Rajgor et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The Reorientation of Cell Nucleus Promotes the Establishment of Front–Rear Polarity in Migrating Fibroblasts

(2013) Miloslava Maninová et al.   JOURNAL OF MOLECULAR BIOLOGY

The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction

(2013) Allison B. Chambliss et al.   Scientific Reports

Matefin/SUN-1 Phosphorylation Is Part of a Surveillance Mechanism to Coordinate Chromosome Synapsis and Recombination with Meiotic Progression and Chromosome Movement

(2013) Alexander Woglar et al.   PLoS Genetics

Accumulation of the Inner Nuclear Envelope Protein Sun1 Is Pathogenic in Progeric and Dystrophic Laminopathies

(2012) Chia-Yen Chen et al.   CELL

Structural insights into SUN-KASH complexes across the nuclear envelope

(2012) Wenjia Wang et al.   CELL RESEARCH

Inner nuclear membrane proteins: impact on human disease

(2012) Iván Méndez-López et al.   CHROMOSOMA

Inner Nuclear Envelope Proteins SUN1 and SUN2 Play a Prominent Role in the DNA Damage Response

(2012) Kai Lei et al.   CURRENT BIOLOGY

Acetylation of the SUN protein Mps3 by Eco1 regulates its function in nuclear organization

(2012) Suman Ghosh et al.   MOLECULAR BIOLOGY OF THE CELL

Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility

(2012) K. Tokuhiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The LINC complex and human disease

(2011) Peter Meinke et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

SPAG4L, a Novel Nuclear Envelope Protein Involved in the Meiotic Stage of Spermatogenesis

(2011) Xian-Zhen Jiang et al.   DNA AND CELL BIOLOGY

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

(2011) Maria L. Lombardi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons

(2011) Catherine Coffinier et al.   MOLECULAR BIOLOGY OF THE CELL

Actomyosin Tension Exerted on the Nucleus through Nesprin-1 Connections Influences Endothelial Cell Adhesion, Migration, and Cyclic Strain-Induced Reorientation

(2010) T.J. Chancellor et al.   BIOPHYSICAL JOURNAL

SPAG4L/SPAG4L-2 are testis-specific SUN domain proteins restricted to the apical nuclear envelope of round spermatids facing the acrosome

(2010) C. Frohnert et al.   MOLECULAR HUMAN REPRODUCTION

Mammalian Sperm Head Formation Involves Different Polarization of Two Novel LINC Complexes

(2010) Eva Göb et al.   PLoS One

Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency

(2010) C. Coffinier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

(2010) G. W. G. Luxton et al.   SCIENCE

The SUN Rises on Meiotic Chromosome Dynamics

(2009) Yasushi Hiraoka et al.   DEVELOPMENTAL CELL

SUN1/2 and Syne/Nesprin-1/2 Complexes Connect Centrosome to the Nucleus during Neurogenesis and Neuronal Migration in Mice

(2009) Xiaochang Zhang et al.   NEURON

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY