Crosstalk of the Androgen Receptor with Transcriptional Collaborators: Potential Therapeutic Targets for Castration-Resistant Prostate Cancer
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Crosstalk of the Androgen Receptor with Transcriptional Collaborators: Potential Therapeutic Targets for Castration-Resistant Prostate Cancer
Authors
Keywords
-
Journal
Cancers
Volume 9, Issue 12, Pages 22
Publisher
MDPI AG
Online
2017-02-28
DOI
10.3390/cancers9030022
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Dual Inhibition of RNA Pol I Transcription and PIM Kinase as a New Therapeutic Approach to Treat Advanced Prostate Cancer
- (2016) Richard J. Rebello et al. CLINICAL CANCER RESEARCH
- Androgen receptor signaling in castration-resistant prostate cancer: a lesson in persistence
- (2016) Isabel Coutinho et al. ENDOCRINE-RELATED CANCER
- SOX9 drives WNT pathway activation in prostate cancer
- (2016) Fen Ma et al. JOURNAL OF CLINICAL INVESTIGATION
- BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer
- (2016) I. A. Asangani et al. MOLECULAR CANCER RESEARCH
- Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth In Vivo
- (2016) Sorah Yoon et al. MOLECULAR THERAPY
- FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression
- (2016) J C Zhao et al. ONCOGENE
- Targeting Oct1 genomic function inhibits androgen receptor signaling and castration-resistant prostate cancer growth
- (2016) D Obinata et al. ONCOGENE
- Moving Beyond the Androgen Receptor (AR): Targeting AR-Interacting Proteins to Treat Prostate Cancer
- (2016) Christopher Foley et al. Hormones & Cancer
- NANOG reprograms prostate cancer cells to castration resistance via dynamically repressing and engaging the AR/FOXA1 signaling axis
- (2016) Collene R Jeter et al. Cell Discovery
- NKX3.1 Suppresses TMPRSS2-ERG Gene Rearrangement and Mediates Repair of Androgen Receptor-Induced DNA Damage
- (2015) C. Bowen et al. CANCER RESEARCH
- Identification of a novel E-box binding pyrrole-imidazole polyamide inhibiting MYC-driven cell proliferation
- (2015) Rajeev Mishra et al. CANCER SCIENCE
- Androgen Receptor Modulation Optimized for Response (ARMOR) Phase I and II Studies: Galeterone for the Treatment of Castration-Resistant Prostate Cancer
- (2015) B. Montgomery et al. CLINICAL CANCER RESEARCH
- The oncogene ERG: a key factor in prostate cancer
- (2015) P Adamo et al. ONCOGENE
- Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model
- (2015) Jun Igarashi et al. PLoS One
- STAT3 regulated ARF expression suppresses prostate cancer metastasis
- (2015) Jan Pencik et al. Nature Communications
- Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide
- (2015) Amanda E. Hargrove et al. PLoS One
- A novel peptide that inhibits E2F transcription and regresses prostate tumor xenografts
- (2015) Xiaoqi Xie et al. Oncotarget
- RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer
- (2015) Ken-ichi Takayama et al. Oncotarget
- Homozygous Deletions and Recurrent Amplifications Implicate New Genes Involved in Prostate Cancer
- (2015) Wennuan Liu et al. NEOPLASIA
- ERG Cooperates with Androgen Receptor in Regulating Trefoil Factor 3 in Prostate Cancer Disease Progression
- (2015) David S. Rickman et al. NEOPLASIA
- CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression
- (2014) K.-i. Takayama et al. CANCER RESEARCH
- Pyrrole-imidazole polyamide targeted to break fusion sites in TMPRSS2 and ERG gene fusion represses prostate tumor growth
- (2014) Daisuke Obinata et al. CANCER SCIENCE
- NFI Transcription Factors Interact with FOXA1 to Regulate Prostate-Specific Gene Expression
- (2014) Magdalena M. Grabowska et al. MOLECULAR ENDOCRINOLOGY
- Integrative Analysis of FOXP1 Function Reveals a Tumor-Suppressive Effect in Prostate Cancer
- (2014) Ken-ichi Takayama et al. MOLECULAR ENDOCRINOLOGY
- AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer
- (2014) Emmanuel S. Antonarakis et al. NEW ENGLAND JOURNAL OF MEDICINE
- Enzalutamide in Metastatic Prostate Cancer before Chemotherapy
- (2014) Tomasz M. Beer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Three-tiered role of the pioneer factor GATA2 in promoting androgen-dependent gene expression in prostate cancer
- (2014) Dayong Wu et al. NUCLEIC ACIDS RESEARCH
- FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer
- (2014) C Gong et al. ONCOGENE
- GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex
- (2014) Bin He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer
- (2014) S. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cooperativity and equilibrium with FOXA1 define the androgen receptor transcriptional program
- (2014) Hong-Jian Jin et al. Nature Communications
- Antitumor and modeling studies of a penetratin-peptide that targets E2F-1 in small cell lung cancer
- (2013) Xiaoqi Xie et al. CANCER BIOLOGY & THERAPY
- Castration-resistant prostate cancer: Adaptive responses in the androgen axis
- (2013) Alison Egan et al. CANCER TREATMENT REVIEWS
- Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer
- (2013) Ken-ichi Takayama et al. EMBO JOURNAL
- The Novel Orally Active Proteasome Inhibitor K-7174 Exerts Anti-myeloma Activityin Vitroandin Vivoby Down-regulating the Expression of Class I Histone Deacetylases
- (2013) Jiro Kikuchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A preclinical xenograft model of prostate cancer using human tumors
- (2013) Mitchell G Lawrence et al. Nature Protocols
- Targeted induction of endogenousNKX3-1by small activating RNA inhibits prostate tumor growth
- (2013) Shancheng Ren et al. PROSTATE
- Molecular Pathogenesis and Progression of Prostate Cancer
- (2013) Randy Schrecengost et al. SEMINARS IN ONCOLOGY
- The Androgen Receptor Induces a Distinct Transcriptional Program in Castration-Resistant Prostate Cancer in Man
- (2012) Naomi L. Sharma et al. CANCER CELL
- ETS1 transcriptional activity is increased in advanced prostate cancer and promotes the castrate-resistant phenotype
- (2012) A.M. Smith et al. CARCINOGENESIS
- Evidence for Efficacy of New Hsp90 Inhibitors Revealed by Ex Vivo Culture of Human Prostate Tumors
- (2012) M. M. Centenera et al. CLINICAL CANCER RESEARCH
- Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity
- (2012) Himisha Beltran et al. EUROPEAN UROLOGY
- Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
- (2012) Howard I. Scher et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines
- (2012) Raja Nhili et al. NUCLEIC ACIDS RESEARCH
- EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent
- (2012) K. Xu et al. SCIENCE
- Dual Roles of PARP-1 Promote Cancer Growth and Progression
- (2012) M. J. Schiewer et al. Cancer Discovery
- FOXA1 Promotes Tumor Progression in Prostate Cancer and Represents a Novel Hallmark of Castration-Resistant Prostate Cancer
- (2011) Josefine Gerhardt et al. AMERICAN JOURNAL OF PATHOLOGY
- Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1
- (2011) Changmeng Cai et al. CANCER CELL
- Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer
- (2011) J. Chad Brenner et al. CANCER CELL
- Phospho-MED1-enhanced UBE2C locus looping drives castration-resistant prostate cancer growth
- (2011) Zhong Chen et al. EMBO JOURNAL
- Randomised phase II study of siltuximab (CNTO 328), an anti-IL-6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer
- (2011) K. Fizazi et al. EUROPEAN JOURNAL OF CANCER
- Pioneer transcription factors: establishing competence for gene expression
- (2011) K. S. Zaret et al. GENES & DEVELOPMENT
- Oct1 regulates cell growth of LNCaP cells and is a prognostic factor for prostate cancer
- (2011) Daisuke Obinata et al. INTERNATIONAL JOURNAL OF CANCER
- Integration of Regulatory Networks by NKX3-1 Promotes Androgen-Dependent Prostate Cancer Survival
- (2011) P. Y. Tan et al. MOLECULAR AND CELLULAR BIOLOGY
- Abiraterone and Increased Survival in Metastatic Prostate Cancer
- (2011) Johann S. de Bono et al. NEW ENGLAND JOURNAL OF MEDICINE
- Enhancing the cellular uptake of Py–Im polyamides through next-generation aryl turns
- (2011) Jordan L. Meier et al. NUCLEIC ACIDS RESEARCH
- YK-4-279 Inhibits ERG and ETV1 Mediated Prostate Cancer Cell Invasion
- (2011) Said Rahim et al. PLoS One
- An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression
- (2010) Jindan Yu et al. CANCER CELL
- Integrative Genomic Profiling of Human Prostate Cancer
- (2010) Barry S. Taylor et al. CANCER CELL
- Overcoming Persistent Dependency on Androgen Signaling after Progression to Castration-Resistant Prostate Cancer
- (2010) M. Yamaoka et al. CLINICAL CANCER RESEARCH
- A review of the electrophilic reaction chemistry involved in covalent DNA binding
- (2010) S. J. Enoch et al. CRITICAL REVIEWS IN TOXICOLOGY
- Conservation of gene linkage in dispersed vertebrate NK homeobox clusters
- (2010) Karl R. Wotton et al. DEVELOPMENT GENES AND EVOLUTION
- The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
- (2010) Ankur Sharma et al. JOURNAL OF CLINICAL INVESTIGATION
- Transcriptional inhibition of progressive renal disease by gene silencing pyrrole–imidazole polyamide targeting of the transforming growth factor-β1 promoter
- (2010) Hiroyuki Matsuda et al. KIDNEY INTERNATIONAL
- Ets-1 Regulates Energy Metabolism in Cancer Cells
- (2010) Meghan L. Verschoor et al. PLoS One
- ETS1 regulates NKX3.1 5′ promoter activity and expression in prostate cancer cells
- (2010) Darren M. Preece et al. PROSTATE
- Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer
- (2010) Karen E. Knudsen et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Pharmacokinetic Modeling and Prediction of Plasma Pyrrole-Imidazole Polyamide Concentration in Rats Using Simultaneous Urinary and Biliary Excretion Data
- (2009) Takashi Nagashima et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Pharmacokinetics of pyrrole-imidazole polyamides after intravenous administration in rat
- (2009) Akiko Fukasawa et al. BIOPHARMACEUTICS & DRUG DISPOSITION
- The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors
- (2009) Michael Hedvat et al. CANCER CELL
- Treatment-Dependent Androgen Receptor Mutations in Prostate Cancer Exploit Multiple Mechanisms to Evade Therapy
- (2009) M. P. Steinkamp et al. CANCER RESEARCH
- Reactivation of Androgen Receptor-Regulated TMPRSS2:ERG Gene Expression in Castration-Resistant Prostate Cancer
- (2009) C. Cai et al. CANCER RESEARCH
- Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer
- (2009) Chunru Lin et al. CELL
- Phase 1 Trial of High-Dose Exogenous Testosterone in Patients with Castration-Resistant Metastatic Prostate Cancer
- (2009) Michael J. Morris et al. EUROPEAN UROLOGY
- A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress
- (2009) J. Kang et al. GENES & DEVELOPMENT
- Androgen Modulation of Coregulator Expression in Prostate Cancer Cells
- (2009) Hannelore V. Heemers et al. MOLECULAR ENDOCRINOLOGY
- c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
- (2009) Ping Gao et al. NATURE
- Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
- (2009) Jennifer C King et al. NATURE GENETICS
- C/EBPα redirects androgen receptor signaling through a unique bimodal interaction
- (2009) J Zhang et al. ONCOGENE
- A role for GATA-2 in transition to an aggressive phenotype in prostate cancer through modulation of key androgen-regulated genes
- (2009) M Böhm et al. ONCOGENE
- Allosteric modulation of DNA by small molecules
- (2009) D. M. Chenoweth et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FOXP1 is an androgen-responsive transcription factor that negatively regulates androgen receptor signaling in prostate cancer cells
- (2008) Kenichi Takayama et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance
- (2008) S. M. Dehm et al. CANCER RESEARCH
- Loss of NKX3.1 Favors Vascular Endothelial Growth Factor-C Expression in Prostate Cancer
- (2008) Heyu Zhang et al. CANCER RESEARCH
- Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer
- (2008) R. Hu et al. CANCER RESEARCH
- FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription
- (2008) Mathieu Lupien et al. CELL
- TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation
- (2008) C Sun et al. ONCOGENE
- Genomic Androgen Receptor-Occupied Regions with Different Functions, Defined by Histone Acetylation, Coregulators and Transcriptional Capacity
- (2008) Li Jia et al. PLoS One
- Inhibition of AR-mediated transcription by binding of Oct1 to a motif enriched in AR-occupied regions
- (2008) Unnati Jariwala et al. PROSTATE
- Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer
- (2008) Scott A. Tomlins et al. NEOPLASIA
- ETS transcription factors: oncogenes and tumor suppressor genes as therapeutic targets for prostate cancer
- (2007) David P Turner et al. Expert Review of Anticancer Therapy
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started