Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines

Ecteinascidin 743 Interferes with the Activity of EWS-FLI1 in Ewing Sarcoma Cells

(2015) Patrick J. Grohar et al.   NEOPLASIA

Targeting a DNA Binding Motif of the EVI1 Protein by a Pyrrole–Imidazole Polyamide

(2011) Yi Zhang et al.   BIOCHEMISTRY

The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis

(2011) G. M. Birdsey et al.   BLOOD

Novel peptide binds EWS-FLI1 and reduces the oncogenic potential in Ewing tumors

(2011) Hayriye V. Erkizan et al.   CELL CYCLE

Synthesis and biological evaluation of N-substituted benzo[c]phenanthrolines and benzo[c]phenanthrolinones as antiproliferative agents

(2011) Constance Genès et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Water-Mediated Binding of Agents that Target the DNA Minor Groove

(2011) Yang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening

(2011) Patrick J. Grohar et al.   JNCI-Journal of the National Cancer Institute

Abnormal Expression of the ERG Transcription Factor in Prostate Cancer Cells Activates Osteopontin

(2011) S. Flajollet et al.   MOLECULAR CANCER RESEARCH

YK-4-279 Inhibits ERG and ETV1 Mediated Prostate Cancer Cell Invasion

(2011) Said Rahim et al.   PLoS One

Comprehensive Study in the Inhibitory Effect of Berberine on Gene Transcription, Including TATA Box

(2011) Yugang Wang et al.   PLoS One

Modulation of NF- B-dependent gene transcription using programmable DNA minor groove binders

(2011) J. A. Raskatov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dicationic phenyl-2,2′-bichalcophenes and analogues as antiprotozoal agents

(2010) Mohamed A. Ismail et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A complex task? Direct modulation of transcription factors with small molecules

(2010) Angela N Koehler   CURRENT OPINION IN CHEMICAL BIOLOGY

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

(2010) Gong-Hong Wei et al.   EMBO JOURNAL

Novel Diamidino-Substituted Derivatives of Phenyl Benzothiazolyl and Dibenzothiazolyl Furans and Thiophenes: Synthesis, Antiproliferative and DNA Binding Properties

(2010) Livio Racané et al.   JOURNAL OF MEDICINAL CHEMISTRY

The E3 ubiquitin ligase complex component COP1 regulates PEA3 group member stability and transcriptional activity

(2010) J-L Baert et al.   ONCOGENE

Minor Groove Binding Compounds That Jump a GC Base Pair and Bind to Adjacent AT Base Pair Sites†

(2009) Maryam Rahimian et al.   BIOCHEMISTRY

Detection of FUS–ERG chimeric transcript in two cases of acute myeloid leukemia with t(16;21)(p11.2;q22) with unusual characteristics

(2009) Juwon Kim et al.   CANCER GENETICS AND CYTOGENETICS

ERG Is a Megakaryocytic Oncogene

(2009) S. Salek-Ardakani et al.   CANCER RESEARCH

ERGExpression Is an Independent Prognostic Factor and Allows Refined Risk Stratification in Cytogenetically Normal Acute Myeloid Leukemia: A Comprehensive Analysis ofERG, MN1, andBAALCTranscript Levels Using Oligonucleotide Microarrays

(2009) Klaus H. Metzeler et al.   JOURNAL OF CLINICAL ONCOLOGY

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

(2009) Hayriye V Erkizan et al.   NATURE MEDICINE

Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin

(2008) G. M. Birdsey et al.   BLOOD

Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer

(2008) Mari Björkman et al.   INTERNATIONAL JOURNAL OF CANCER

Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication

(2008) Paul Peixoto et al.   NUCLEIC ACIDS RESEARCH

Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer

(2008) Scott A. Tomlins et al.   NEOPLASIA