Pleiotropic Roles of Non-Coding RNAs in TGF-β-Mediated Epithelial-Mesenchymal Transition and Their Functions in Tumor Progression

Circular RNAs in cancer: an emerging key player

(2017) Yeping Dong et al.   Journal of Hematology & Oncology

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

(2017) Angela M. Krebs et al.   NATURE CELL BIOLOGY

SPOt: A novel and streamlined microarray platform for observing cellular tRNA levels

(2017) Simon Grelet et al.   PLoS One

Grhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancer

(2017) J Xiang et al.   Oncogenesis

Tissue Factor Induced by Epithelial–Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells

(2016) Morgane Bourcy et al.   CANCER RESEARCH

Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression

(2016) Hani Goodarzi et al.   CELL

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Coordinating cell proliferation and differentiation: Antagonism between cell cycle regulators and cell type-specific gene expression

(2016) Suzan Ruijtenberg et al.   CELL CYCLE

High expression of long non-coding RNA ATB indicates a poor prognosis and regulates cell proliferation and metastasis in non-small cell lung cancer

(2016) L. Ke et al.   Clinical & Translational Oncology

MEG3 Long Noncoding RNA Contributes to the Epigenetic Regulation of Epithelial-Mesenchymal Transition in Lung Cancer Cell Lines

(2016) Minoru Terashima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications

(2016) Silvia Juliana Serrano-Gomez et al.   Molecular Cancer

Piwi-interacting RNAs in cancer: emerging functions and clinical utility

(2016) Kevin W. Ng et al.   Molecular Cancer

Long non-coding RNA ATB promotes growth and epithelial-mesenchymal transition and predicts poor prognosis in human prostate carcinoma

(2016) SONG XU et al.   ONCOLOGY REPORTS

Biogenesis and Function of Transfer RNA-Related Fragments (tRFs)

(2016) Pankaj Kumar et al.   TRENDS IN BIOCHEMICAL SCIENCES

Epithelialization of mouse ovarian tumor cells originating in the fallopian tube stroma

(2016) Yuanyuan Hua et al.   Oncotarget

Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States

(2016) Konrad L. M. Rudolph et al.   PLoS Genetics

Role of EMT in Metastasis and Therapy Resistance

(2016) Bethany Smith et al.   Journal of Clinical Medicine

Circulating biomarkers to monitor cancer progression and treatment

(2016) Suthee Rapisuwon et al.   Computational and Structural Biotechnology Journal

Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205

(2015) H. Hirata et al.   CANCER RESEARCH

The RNA Binding Protein Quaking Regulates Formation of circRNAs

(2015) Simon J. Conn et al.   CELL

Long Non-coding RNAs (LncRNA) Regulated by Transforming Growth Factor (TGF) β

(2015) Edward J. Richards et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The humanNANOS3gene contributes to lung tumour invasion by inducing epithelial-mesenchymal transition

(2015) Simon Grelet et al.   JOURNAL OF PATHOLOGY

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs

(2015) Eric Londin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elf5 inhibits TGF-β-driven epithelial-mesenchymal transition in prostate cancer by repressing SMAD3 activation

(2015) Bing Yao et al.   PROSTATE

MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures

(2015) Tanmoy Mondal et al.   Nature Communications

LncRNA-ATB promotes trastuzumab resistance and invasion-metastasis cascade in breast cancer

(2015) Sheng-Jia Shi et al.   Oncotarget

TGFβ1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT

(2015) Junlong Zhuang et al.   Scientific Reports

MicroRNA-720 promotes in vitro cell migration by targeting Rab35 expression in cervical cancer cells

(2015) Yunlan Tang et al.   Cell and Bioscience

Long Noncoding RNAs as New Architects in Cancer Epigenetics, Prognostic Biomarkers, and Potential Therapeutic Targets

(2015) Didier Meseure et al.   Biomed Research International

RNA sequencing identifies specific PIWI-interacting small non-coding RNA expression patterns in breast cancer

(2015) Adnan Hashim et al.   Oncotarget

Epigenetic plasticity: A central regulator of epithelial-to-mesenchymal transition in cancer

(2015) Upasana Bedi et al.   Oncotarget

Correlation of circular RNA abundance with proliferation – exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis and normal human tissues

(2015) Anna Bachmayr-Heyda et al.   Scientific Reports

The Roles of the Epithelial-Mesenchymal Transition Marker PRRX1 and miR-146b-5p in Papillary Thyroid Carcinoma Progression

(2014) Heather Hardin et al.   AMERICAN JOURNAL OF PATHOLOGY

A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma

(2014) Ji-hang Yuan et al.   CANCER CELL

A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation

(2014) Hila Gingold et al.   CELL

TGF- -Induced Upregulation of malat1 Promotes Bladder Cancer Metastasis by Associating with suz12

(2014) Y. Fan et al.   CLINICAL CANCER RESEARCH

TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells

(2014) Horacio Cardenas et al.   Epigenetics

Angiogenin-Cleaved tRNA Halves Interact with Cytochrome c, Protecting Cells from Apoptosis during Osmotic Stress

(2014) M. Saikia et al.   MOLECULAR AND CELLULAR BIOLOGY

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long non-coding RNA HOTAIR is a powerful predictor of metastasis and poor prognosis and is associated with epithelial-mesenchymal transition in colon cancer

(2014) ZE-HUA WU et al.   ONCOLOGY REPORTS

Molecular function and regulation of long non-coding RNAs: paradigms with potential roles in cancer

(2014) Mohammadreza Hajjari et al.   TUMOR BIOLOGY

LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis

(2014) Xiaodan Ji et al.   eLife

Large noncoding RNA HOTAIR enhances aggressive biological behavior and is associated with short disease-free survival in human non-small cell lung cancer

(2013) Takayuki Nakagawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long non-coding RNAs: A new frontier in the study of human diseases

(2013) Xuefei Shi et al.   CANCER LETTERS

Circular RNA and miR-7 in Cancer

(2013) T. B. Hansen et al.   CANCER RESEARCH

Signaling between Transforming Growth Factor β (TGF-β) and Transcription Factor SNAI2 Represses Expression of MicroRNA miR-203 to Promote Epithelial-Mesenchymal Transition and Tumor Metastasis

(2013) Xiangming Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KLF8 involves in TGF-beta-induced EMT and promotes invasion and migration in gastric cancer cells

(2013) Hui Zhang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

An Autocrine Loop between TGF- 1 and the Transcription Factor Brachyury Controls the Transition of Human Carcinoma Cells into a Mesenchymal Phenotype

(2013) C. Larocca et al.   MOLECULAR CANCER THERAPEUTICS

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Promiscuous RNA binding by Polycomb repressive complex 2

(2013) Chen Davidovich et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Elevated snoRNA biogenesis is essential in breast cancer

(2013) H Su et al.   ONCOGENE

The expression of stem cell protein Piwil2 and piR-932 in breast cancer

(2013) Hao Zhang et al.   SURGICAL ONCOLOGY-OXFORD

Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells

(2013) Joëlle Roche et al.   Cancers

Altered expression of piRNAs and their relation with clinicopathologic features of breast cancer

(2012) G. Huang et al.   Clinical & Translational Oncology

A Transgenic Mouse Marking Live Replicating Cells Reveals In Vivo Transcriptional Program of Proliferation

(2012) Agnes Klochendler et al.   DEVELOPMENTAL CELL

MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms

(2012) Y-N Liu et al.   ONCOGENE

Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation

(2012) S M Kumar et al.   ONCOGENE

Establishment of a TGFβ-Induced Post-Transcriptional EMT Gene Signature

(2012) George S. Hussey et al.   PLoS One

An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

(2011) Philip A. Gregory et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of an mRNP Complex Regulating Tumorigenesis at the Translational Elongation Step

(2011) George S. Hussey et al.   MOLECULAR CELL

Determinants of translation efficiency and accuracy

(2011) H. Gingold et al.   Molecular Systems Biology

The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?

(2010) Simone Brabletz et al.   EMBO REPORTS

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

TGF-β-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI

(2010) Arindam Chaudhury et al.   NATURE CELL BIOLOGY

Translational Activation of Snail1 and Other Developmentally Regulated Transcription Factors by YB-1 Promotes an Epithelial-Mesenchymal Transition

(2009) Valentina Evdokimova et al.   CANCER CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

A novel class of small RNAs: tRNA-derived RNA fragments (tRFs)

(2009) Yong Sun Lee et al.   GENES & DEVELOPMENT

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

tRNA over-expression in breast cancer and functional consequences

(2009) Mariana Pavon-Eternod et al.   NUCLEIC ACIDS RESEARCH

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs

(2009) C. Cole et al.   RNA

TGFβ in Cancer

(2008) Joan Massagué   CELL

Stress induces tRNA cleavage by angiogenin in mammalian cells

(2008) Hanjiang Fu et al.   FEBS LETTERS

A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition

(2008) M. Beltran et al.   GENES & DEVELOPMENT

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY