Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells

ZEB-1, a Repressor of the Semaphorin 3F Tumor Suppressor Gene in Lung Cancer Cells

(2015) Jonathan Clarhaut et al.   NEOPLASIA

Distinct HIC1-SIRT1-p53 Loop Deregulation in Lung Squamous Carcinoma and Adenocarcinoma Patients

(2015) Ruo-Chia Tseng et al.   NEOPLASIA

Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers

(2012) Ramaswamy Govindan et al.   CELL

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

(2012) Marcin Imielinski et al.   CELL

Evolutionary functional analysis and molecular regulation of the ZEB transcription factors

(2012) Alexander Gheldof et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A new generation of EGFR tyrosine-kinase inhibitors in NSCLC

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Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

(2012) Rafael Rosell et al.   LANCET ONCOLOGY

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

(2012) Michael T. McCabe et al.   NATURE

DNA methylation profiling in the clinic: applications and challenges

(2012) Holger Heyn et al.   NATURE REVIEWS GENETICS

SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis

(2012) V Byles et al.   ONCOGENE

Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis

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Circulating Tumor Cells as a Window on Metastasis Biology in Lung Cancer

(2011) Jian-Mei Hou et al.   AMERICAN JOURNAL OF PATHOLOGY

Targets of the Tumor Suppressor miR-200 in Regulation of the Epithelial-Mesenchymal Transition in Cancer

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ATP-dependent chromatin remodeling: genetics, genomics and mechanisms

(2011) Diana C Hargreaves et al.   CELL RESEARCH

Multifaceted Role of Neuropilins in Cancer

(2011) S. Rizzolio et al.   CURRENT MEDICINAL CHEMISTRY

Rab25 and CLIC3 Collaborate to Promote Integrin Recycling from Late Endosomes/Lysosomes and Drive Cancer Progression

(2011) Marta A. Dozynkiewicz et al.   DEVELOPMENTAL CELL

Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer

(2011) Ali Aghdassi et al.   GUT

A ZEB1-HDAC pathway enters the epithelial to mesenchymal transition world in pancreatic cancer: Figure 1

(2011) Günter Schneider et al.   GUT

Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study

(2011) Caicun Zhou et al.   LANCET ONCOLOGY

Gefitinib as first-line treatment for patients with advanced non-small-cell lung cancer with activating Epidermal Growth Factor Receptor mutation: Implications for clinical practice and open issues

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The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non-Small Cell Lung Cancer

(2011) R. A. Juergens et al.   Cancer Discovery

Rab25 as a tumour suppressor in colon carcinogenesis

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Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) gene, suppresses anchorage-independent cell growth of lung cancer cells

(2010) Yoshihiro Takeyama et al.   CANCER LETTERS

ZEB1-responsive genes in non-small cell lung cancer

(2010) Robert M. Gemmill et al.   CANCER LETTERS

H3K9 Histone Methyltransferase G9a Promotes Lung Cancer Invasion and Metastasis by Silencing the Cell Adhesion Molecule Ep-CAM

(2010) M.-W. Chen et al.   CANCER RESEARCH

Histone methyltransferase G9a contributes to H3K27 methylation in vivo

(2010) Hui Wu et al.   CELL RESEARCH

The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?

(2010) Simone Brabletz et al.   EMBO REPORTS

Induction of E-Cadherin in Lung Cancer and Interaction with Growth Suppression by Histone Deacetylase Inhibition

(2010) Masatoshi Kakihana et al.   Journal of Thoracic Oncology

Cancer-Associated Fibroblasts Derived from EGFR-TKI-Resistant Tumors Reverse EGFR Pathway Inhibition by EGFR-TKIs

(2010) S. R. Mink et al.   MOLECULAR CANCER RESEARCH

Loss of miR-200c Expression Induces an Aggressive, Invasive, and Chemoresistant Phenotype in Non-Small Cell Lung Cancer

(2010) P. Ceppi et al.   MOLECULAR CANCER RESEARCH

ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1

(2010) E Sánchez-Tilló et al.   ONCOGENE

Lung cancer

(2010) Arnaud Van Den Broeck et al.   Cell Adhesion & Migration

Global Levels of Histone Modifications Predict Prognosis in Different Cancers

(2009) David B. Seligson et al.   AMERICAN JOURNAL OF PATHOLOGY

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The Emerging Role of the RAB25 Small GTPase in Cancer

(2009) Roshan Agarwal et al.   TRAFFIC

Rabs and cancer cell motility

(2009) Bor Luen Tang et al.   CELL MOTILITY AND THE CYTOSKELETON

Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells

(2008) Hideo Watanabe et al.   Cancer Cell International

Loss of Histone H4K20 Trimethylation Occurs in Preneoplasia and Influences Prognosis of Non-Small Cell Lung Cancer

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Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers

(2008) Michèle Sabbah et al.   DRUG RESISTANCE UPDATES