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Title
New Insights into the Mechanism of Action of Soluble Klotho
Authors
Keywords
-
Journal
Frontiers in Endocrinology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-11-17
DOI
10.3389/fendo.2017.00323
References
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- The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging
- (2016) C-C Hsieh et al. Aging-US
- Reduced expression and growth inhibitory activity of the aging suppressor klotho in epithelial ovarian cancer
- (2015) Irina Lojkin et al. CANCER LETTERS
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- (2015) I. R. Nabi et al. JOURNAL OF CELL SCIENCE
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- (2015) Kenneth Lim et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Renal Production, Uptake, and Handling of Circulating Klotho
- (2015) M. C. Hu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma
- (2015) Xiaowei Tang et al. LABORATORY INVESTIGATION
- Soluble Serum αKlotho Is a Potential Predictive Marker of Disease Progression in Clear Cell Renal Cell Carcinoma
- (2015) Margherita Gigante et al. MEDICINE
- microRNA miR-10b inhibition reduces cell proliferation and promotes apoptosis in non-small cell lung cancer (NSCLC) cells
- (2015) Junchao Huang et al. Molecular BioSystems
- Tumor Suppressor Activity of Klotho in Breast Cancer Is Revealed by Structure-Function Analysis
- (2015) H. Ligumsky et al. MOLECULAR CANCER RESEARCH
- Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling Pathways
- (2015) Reynolds K. Brobey et al. PLoS One
- α-Klotho protects against oxidative damage in pulmonary epithelia
- (2014) Priya Ravikumar et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
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- (2014) Ci-Di Chen et al. BIOCHEMISTRY
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- (2014) J. Xie et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
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- (2013) Biao Xie et al. Cancer Cell International
- Biochemical and Functional Characterization of the Klotho-VS Polymorphism Implicated in Aging and Disease Risk
- (2013) Tracey B. Tucker Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Klotho, phosphate and FGF-23 in ageing and disturbed mineral metabolism
- (2013) Makoto Kuro-o Nature Reviews Nephrology
- Klotho gene delivery suppresses Nox2 expression and attenuates oxidative stress in rat aortic smooth muscle cells via the cAMP-PKA pathway
- (2012) Yuhong Wang et al. AGING CELL
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- (2012) Bo Chen et al. CANCER BIOLOGY & THERAPY
- Vascular Klotho Deficiency Potentiates the Development of Human Artery Calcification and Mediates Resistance to Fibroblast Growth Factor 23
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- Serum levels of soluble secreted α-Klotho are decreased in the early stages of chronic kidney disease, making it a probable novel biomarker for early diagnosis
- (2012) Yoshiko Shimamura et al. Clinical and Experimental Nephrology
- Characteristics of urinary and serum soluble Klotho protein in patients with different degrees of chronic kidney disease
- (2012) Tetsu Akimoto et al. BMC Nephrology
- Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart
- (2012) Jian Xie et al. Nature Communications
- Restoration of klotho expression induces apoptosis and autophagy in hepatocellular carcinoma cells
- (2012) Guoshun Shu et al. CELLULAR ONCOLOGY
- Epigenetic silencing of the tumor suppressor klotho in human breast cancer
- (2011) Tami Rubinek et al. BREAST CANCER RESEARCH AND TREATMENT
- KL1 Internal Repeat Mediates Klotho Tumor Suppressor Activities and Inhibits bFGF and IGF-I Signaling in Pancreatic Cancer
- (2011) L. Abramovitz et al. CLINICAL CANCER RESEARCH
- Klotho protein diminishes endothelial apoptosis and senescence via a mitogen-activated kinase pathway
- (2011) Yoshihiro Maekawa et al. Geriatrics & Gerontology International
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- (2011) Shigehiro Doi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Christian Faul et al. JOURNAL OF CLINICAL INVESTIGATION
- Plasma Klotho and Cardiovascular Disease in Adults
- (2011) Richard D. Semba et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
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- (2011) Chou-Long Huang et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
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- (2011) Jie Pan et al. TUMOR BIOLOGY
- From endothelial dysfunction to atherosclerosis
- (2010) S. Sitia et al. AUTOIMMUNITY REVIEWS
- Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects
- (2010) Yuji Yamazaki et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2010) Stefano Taddei et al. HEART FAILURE REVIEWS
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- (2010) Bo Chen et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
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- (2010) Tijana Krajisnik et al. KIDNEY INTERNATIONAL
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- (2010) Jaehyouk Lee et al. Molecular Cancer
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- (2010) Vidya Ganapathy et al. Molecular Cancer
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- (2010) Tura C. Camilli et al. Pigment Cell & Melanoma Research
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- (2010) X. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) Hiroshi Kurosu et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
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- (2008) I Wolf et al. ONCOGENE
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- (2008) S.-K. Cha et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NON-CORONARY HEART DISEASE IN DIALYSIS PATIENTS: Hypertrophy and Fibrosis in the Cardiomyopathy of Uremia-Beyond Coronary Heart Disease
- (2008) Marie-Luise Gross et al. SEMINARS IN DIALYSIS
- Gene profile analysis implicates Klotho as an important contributor to aging changes in brain white matter of the rhesus monkey
- (2007) James A. Duce et al. GLIA
- THE CLINICAL EPIDEMIOLOGY OF CARDIOVASCULAR DISEASES IN CHRONIC KIDNEY DISEASE: Cardiovascular Disease in Chronic Renal Failure: Pathophysiologic Aspects
- (2004) Gérard M. London SEMINARS IN DIALYSIS
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