Modeled structural basis for the recognition of α2-3-sialyllactose by soluble Klotho

Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling

(2017) George Dalton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Combining Crystallography and Hydrogen-Deuterium Exchange to Study Galectin-Ligand Complexes

(2015) Federico M. Ruiz et al.   CHEMISTRY-A EUROPEAN JOURNAL

Streptococcus pneumoniaeNanC

(2015) C. David Owen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB

(2015) James A. Maier et al.   Journal of Chemical Theory and Computation

DOCK 6: Impact of new features and current docking performance

(2015) William J. Allen et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Life Extension Factor Klotho Prevents Mortality and Enhances Cognition in hAPP Transgenic Mice

(2015) D. B. Dubal et al.   JOURNAL OF NEUROSCIENCE

Soluble Klotho Protects against Uremic Cardiomyopathy Independently of Fibroblast Growth Factor 23 and Phosphate

(2014) J. Xie et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Prevention of influenza by targeting host receptors using engineered proteins

(2014) H. Connaris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Life Extension Factor Klotho Enhances Cognition

(2014) Dena B. Dubal et al.   Cell Reports

Biochemical and Functional Characterization of the Klotho-VS Polymorphism Implicated in Aging and Disease Risk

(2013) Tracey B. Tucker Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-resolution structures ofNeotermes koshunensisβ-glucosidase mutants provide insights into the catalytic mechanism and the synthesis of glucoconjugates

(2012) Wen-Yih Jeng et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart

(2012) Jian Xie et al.   Nature Communications

Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice

(2011) Shigehiro Doi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Klotho suppresses RIG-I-mediated senescence-associated inflammation

(2011) Feng Liu et al.   NATURE CELL BIOLOGY

Membrane Organization and Lipid Rafts

(2011) K. Simons et al.   Cold Spring Harbor Perspectives in Biology

Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer

(2008) I Wolf et al.   ONCOGENE

Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

(2008) S.-K. Cha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA