Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus

Regulation of Brain-Derived Neurotrophic Factor Exocytosis and Gamma-Aminobutyric Acidergic Interneuron Synapse by the Schizophrenia Susceptibility Gene Dysbindin-1

(2016) Qiang Yuan et al.   BIOLOGICAL PSYCHIATRY

The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse

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Lack of the effect of bumetanide, a selective NKCC1 inhibitor, in patients with schizophrenia: A double-blind randomized trial

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Global, quantitative and dynamic mapping of protein subcellular localization

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Alterations in Cortical Network Oscillations and Parvalbumin Neurons in Schizophrenia

(2015) Guillermo Gonzalez-Burgos et al.   BIOLOGICAL PSYCHIATRY

FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

(2015) Jessica Mariani et al.   CELL

The KCNE2 K+ channel regulatory subunit: Ubiquitous influence, complex pathobiology

(2015) Geoffrey W. Abbott   GENE

Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor

(2015) Avanti Gokhale et al.   HUMAN MOLECULAR GENETICS

The N-Ethylmaleimide-Sensitive Factor and Dysbindin Interact To Modulate Synaptic Plasticity

(2015) A. Gokhale et al.   JOURNAL OF NEUROSCIENCE

Gene Dosage in the Dysbindin Schizophrenia Susceptibility Network Differentially Affect Synaptic Function and Plasticity

(2015) A. P. Mullin et al.   JOURNAL OF NEUROSCIENCE

Evaluating historical candidate genes for schizophrenia

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Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome

(2015) Gabriele Deidda et al.   NATURE MEDICINE

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

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Comparative density of CCK- and PV-GABA cells within the cortex and hippocampus

(2015) Paul D. Whissell et al.   Frontiers in Neuroanatomy

Lack of parvalbumin in mice leads to behavioral deficits relevant to all human autism core symptoms and related neural morphofunctional abnormalities

(2015) M Wöhr et al.   Translational Psychiatry

Decreased Chloride Channel Expression in the Dorsolateral Prefrontal Cortex in Schizophrenia

(2015) Courtney R. Sullivan et al.   PLoS One

The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy

(2014) C. McCloskey et al.   EMBO Molecular Medicine

Mutations in the BLOC-1 Subunits Dysbindin and Muted Generate Divergent and Dosage-dependent Phenotypes

(2014) Jennifer Larimore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Cation-chloride cotransporters in neuronal development, plasticity and disease

(2014) Kai Kaila et al.   NATURE REVIEWS NEUROSCIENCE

KCNQ1, KCNE2, and Na+-Coupled Solute Transporters Form Reciprocally Regulating Complexes That Affect Neuronal Excitability

(2014) G. W. Abbott et al.   Science Signaling

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Erbb4 Deletion from Fast-Spiking Interneurons Causes Schizophrenia-like Phenotypes

(2013) Isabel del Pino et al.   NEURON

MeCP2 Regulates the Synaptic Expression of a Dysbindin-BLOC-1 Network Component in Mouse Brain and Human Induced Pluripotent Stem Cell-Derived Neurons

(2013) Jennifer Larimore et al.   PLoS One

The DTNBP1 (dysbindin-1) gene variant rs2619522 is associated with variation of hippocampal and prefrontal grey matter volumes in humans

(2012) S. Trost et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Snapin is Critical for Presynaptic Homeostatic Plasticity

(2012) D. K. Dickman et al.   JOURNAL OF NEUROSCIENCE

Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction

(2012) M Ayalew et al.   MOLECULAR PSYCHIATRY

Autistic-like behaviour in Scn1a +/− mice and rescue by enhanced GABA-mediated neurotransmission

(2012) Sung Han et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Interneuron dysfunction in psychiatric disorders

(2012) Oscar Marín   NATURE REVIEWS NEUROSCIENCE

Cation-chloride cotransporters NKCC1 and KCC2 as potential targets for novel antiepileptic and antiepileptogenic treatments

(2012) Wolfgang Löscher et al.   NEUROPHARMACOLOGY

GeneCodis3: a non-redundant and modular enrichment analysis tool for functional genomics

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Targeted Deletion of Kcne2 Impairs HCN Channel Function in Mouse Thalamocortical Circuits

(2012) Shui-Wang Ying et al.   PLoS One

Dysbindin-Containing Complexes and their Proposed Functions in Brain: From Zero to (too) Many in a Decade

(2011) Cristina A Ghiani et al.   ASN Neuro

KCNE1 and KCNE2 Inhibit Forward Trafficking of Homomeric N-Type Voltage-Gated Potassium Channels

(2011) Vikram A. Kanda et al.   BIOPHYSICAL JOURNAL

KCNE1 and KCNE2 Provide a Checkpoint Governing Voltage-Gated Potassium Channel α-Subunit Composition

(2011) Vikram A. Kanda et al.   BIOPHYSICAL JOURNAL

Protein kinase C downregulates IKs by stimulating KCNQ1-KCNE1 potassium channel endocytosis

(2011) Vikram A. Kanda et al.   HEART RHYTHM

Effects of DTNBP1 genotype on brain development in children

(2011) Stefania Tognin et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Expression of GABA Signaling Molecules KCC2, NKCC1, and GAD1 in Cortical Development and Schizophrenia

(2011) T. M. Hyde et al.   JOURNAL OF NEUROSCIENCE

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse

(2011) Jennifer Larimore et al.   MOLECULAR BIOLOGY OF THE CELL

Cell Biology of the BLOC-1 Complex Subunit Dysbindin, a Schizophrenia Susceptibility Gene

(2011) Ariana P. Mullin et al.   MOLECULAR NEUROBIOLOGY

The Na+/Ca2+ exchanger NCKX4 governs termination and adaptation of the mammalian olfactory response

(2011) Aaron B Stephan et al.   NATURE NEUROSCIENCE

Synaptic Dysbindin-1 Reductions in Schizophrenia Occur in an Isoform-Specific Manner Indicating Their Subsynaptic Location

(2011) Konrad Talbot et al.   PLoS One

Functional Analysis beyond Enrichment: Non-Redundant Reciprocal Linkage of Genes and Biological Terms

(2011) Celia Fontanillo et al.   PLoS One

Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila

(2011) L. Shao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia

(2011) G. C. Carlson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced Dysbindin Expression Mediates N-Methyl-D-Aspartate Receptor Hypofunction and Impaired Working Memory Performance

(2010) Katherine H. Karlsgodt et al.   BIOLOGICAL PSYCHIATRY

Blocking Early GABA Depolarization with Bumetanide Results in Permanent Alterations in Cortical Circuits and Sensorimotor Gating Deficits

(2010) Doris D. Wang et al.   CEREBRAL CORTEX

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

Dysbindin C–A–T haplotype is associated with thicker medial orbitofrontal cortex in healthy population

(2010) Antonio Cerasa et al.   NEUROIMAGE

Impact of schizophrenia-risk gene dysbindin 1 on brain activation in bilateral middle frontal gyrus during a working memory task in healthy individuals

(2009) Valentin Markov et al.   HUMAN BRAIN MAPPING

Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency

(2009) Verónica T. Cheli et al.   HUMAN MOLECULAR GENETICS

Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression

(2009) J. Tang et al.   HUMAN MOLECULAR GENETICS

Common circuit defect of excitatory-inhibitory balance in mouse models of autism

(2009) Nadine Gogolla et al.   Journal of Neurodevelopmental Disorders

Dysbindin-1 genotype effects on emotional working memory

(2009) C Wolf et al.   MOLECULAR PSYCHIATRY

The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth

(2009) C A Ghiani et al.   MOLECULAR PSYCHIATRY

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Genetic variation in schizophrenia-risk-gene dysbindin 1 modulates brain activation in anterior cingulate cortex and right temporal gyrus during language production in healthy individuals

(2009) V. Markov et al.   NEUROIMAGE

Dysbindin modulates brain function during visual processing in children

(2009) A. Mechelli et al.   NEUROIMAGE

Dysbindin Modulates Prefrontal Cortical Glutamatergic Circuits and Working Memory Function in Mice

(2009) James David Jentsch et al.   NEUROPSYCHOPHARMACOLOGY

Role of dysbindin in dopamine receptor trafficking and cortical GABA function

(2009) Y. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Schizophrenia Susceptibility Gene dysbindin Controls Synaptic Homeostasis

(2009) D. K. Dickman et al.   SCIENCE

Conserved Regional Patterns of GABA-Related Transcript Expression in the Neocortex of Subjects With Schizophrenia

(2008) Takanori Hashimoto et al.   AMERICAN JOURNAL OF PSYCHIATRY

Variation in the dysbindin gene and normal cognitive function in three independent population samples

(2008) M. Luciano et al.   GENES BRAIN AND BEHAVIOR

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS