Synthesis of spiropyrazoline oxindoles by a formal [4 + 1] annulation reaction between 3-bromooxindoles and in situ-derived 1,2-diaza-1,3-dienes
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Synthesis of spiropyrazoline oxindoles by a formal [4 + 1] annulation reaction between 3-bromooxindoles and in situ-derived 1,2-diaza-1,3-dienes
Authors
Keywords
-
Journal
Organic Chemistry Frontiers
Volume 4, Issue 7, Pages 1289-1293
Publisher
Royal Society of Chemistry (RSC)
Online
2017-03-28
DOI
10.1039/c7qo00163k
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Copper(I)-Catalyzed Asymmetric 1,3-Dipolar [3+4] Cycloaddition of Nitrones with Azoalkenes
- (2016) Liang Wei et al. ADVANCED SYNTHESIS & CATALYSIS
- Construction of 2,3,4,7-Tetrahydro-1,2,4,5-oxatriazepines via [4+3] Cycloadditions of α-Halogeno Hydrazones with Nitrones
- (2016) Hong-Wu Zhao et al. ADVANCED SYNTHESIS & CATALYSIS
- Asymmetric Synthesis of Spirobenzazepinones with Atroposelectivity and Spiro-1,2-Diazepinones by NHC-Catalyzed [3+4] Annulation Reactions
- (2016) Lei Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Natural Product-Derived Spirooxindole Fragments Serve as Privileged Substructures for Discovery of New Anticancer Agents
- (2016) Bin Yu et al. Anti-Cancer Agents in Medicinal Chemistry
- Fluoride-Assisted Synthesis of 1,4,5,6-Tetrahydropyridazines via [4 + 2] Cyclodimerization of in Situ-Generated Azoalkenes Followed by a C–N Bond Cleavage
- (2016) Anil M. Shelke et al. ORGANIC LETTERS
- TEMPO-Mediated Aza-Diels–Alder Reaction: Synthesis of Tetrahydropyridazines Using Ketohydrazones and Olefins
- (2016) Xiu-Long Yang et al. ORGANIC LETTERS
- Oxidative Radical Addition–Cyclization of Sulfonyl Hydrazones with Simple Olefins by Binary Acid Catalysis
- (2016) Xingren Zhong et al. ORGANIC LETTERS
- Direct access to non-aromatic 1,2,3,6-tetrahydro-1,2,3,4-tetrazines via [4 + 2] cycloaddition of α-halogeno hydrazones with azodicarboxylic acid derivatives
- (2016) Hong-Wu Zhao et al. RSC Advances
- Therapeutic Potential of Spirooxindoles as Antiviral Agents
- (2016) Na Ye et al. ACS Infectious Diseases
- The catalytic asymmetric synthesis of tetrahydropyridazines via inverse electron-demand aza-Diels–Alder reaction of enol ethers with azoalkenes
- (2015) Liang Wei et al. CHEMICAL COMMUNICATIONS
- Formal [4+1] Annulation Reactions in the Synthesis of Carbocyclic and Heterocyclic Systems
- (2015) Jia-Rong Chen et al. CHEMICAL REVIEWS
- Spirooxindoles: Promising scaffolds for anticancer agents
- (2015) Bin Yu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of orally active anticancer candidate CFI-400945 derived from biologically promising spirooxindoles: Success and challenges
- (2015) Bin Yu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Enantioselective [4 + 1] Annulation Reactions of α-Substituted Ammonium Ylides To Construct Spirocyclic Oxindoles
- (2015) Peng-Fei Zheng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Catalytic Asymmetric Cascade Vinylogous Mukaiyama 1,6-Michael/Michael Addition of 2-Silyloxyfurans with Azoalkenes: Direct Approach to Fused Butyrolactones
- (2015) Jun Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Molecular diversity of spirooxindoles. Synthesis and biological activity
- (2015) Tetyana L. Pavlovska et al. MOLECULAR DIVERSITY
- Synthesis of novel symmetrical 2-oxo-spiro[indole-3,4′-pyridines] by a reaction of oxindoles with 1,2-diaza-1,3-dienes
- (2015) Orazio A. Attanasi et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Ylide formal [4 + 1] annulation
- (2015) Chunyin Zhu et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Substrate-controlled product-selectivity in the reaction of the Bestmann–Ohira reagent with N-unprotected isatin-derived olefins
- (2015) Ashis Kumar Gupta et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- [4 + 2] Cycloaddition of in Situ Generated 1,2-Diaza-1,3-dienes with Simple Olefins: Facile Approaches to Tetrahydropyridazines
- (2015) Xingren Zhong et al. ORGANIC LETTERS
- Divergent Construction of Pyrazoles via Michael Addition of N-Arylhydrazones to 1,2-Diaza-1,3-dienes
- (2015) Serena Mantenuto et al. ORGANIC LETTERS
- Organocatalytic Enantioselective 1,3-Dipolar Cycloadditions between Seyferth–Gilbert Reagent and Isatylidene Malononitriles: Synthesis of Chiral Spiro-phosphonylpyrazoline-oxindoles
- (2015) Taiping Du et al. ORGANIC LETTERS
- Catalytic Asymmetric Synthesis of [2,3]-Fused Indoline Heterocycles through Inverse-Electron-Demand Aza-Diels-Alder Reaction of Indoles with Azoalkenes
- (2014) Min-Chao Tong et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of novel spiropyrazoline oxindoles and evaluation of cytotoxicity in cancer cell lines
- (2014) Ângelo Monteiro et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and antimicrobial activity of some novel 2-thienyl substituted heterocycles
- (2014) Mohamed Salah K. Youssef et al. HETEROCYCLIC COMMUNICATIONS
- Synthesis and Antimicrobial Evaluation of Some New Spiroindolinone Derivatives
- (2014) Hala M. Refat JOURNAL OF HETEROCYCLIC CHEMISTRY
- N-Heterocyclic Carbene Catalyzed Switchable Reactions of Enals with Azoalkenes: Formal [4 + 3] and [4 + 1] Annulations for the Synthesis of 1,2-Diazepines and Pyrazoles
- (2014) Chang Guo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Recent advances in the synthesis of biologically active spirooxindoles
- (2014) Maria M.M. Santos TETRAHEDRON
- Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies
- (2014) Daojuan Cheng et al. ACS Catalysis
- Copper-Catalyzed Enantioselective Inverse Electron-Demand Hetero-Diels-Alder Reactions of Diazadienes with Enol Ethers: Efficient Synthesis of Chiral Pyridazines
- (2013) Shuang Gao et al. ADVANCED SYNTHESIS & CATALYSIS
- Recent Advances in Asymmetric Organocatalytic Construction of 3,3′-Spirocyclic Oxindoles
- (2013) Liang Hong et al. ADVANCED SYNTHESIS & CATALYSIS
- [4+3] Cycloaddition of in situ generated azoalkenes with C,N-cyclic azomethine imines: efficient synthesis of tetrazepine derivatives
- (2013) Xiao-Qiang Hu et al. CHEMICAL COMMUNICATIONS
- 4,5-Dihydro-1H-pyrazole: an indispensable scaffold
- (2013) Jimi Marin Alex et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Pyrazolines: A Biological Review
- (2013) Akranth Marella et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones
- (2013) Anthony L. Gerten et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Synthesis and Antimicrobial and Antifungal Activity of Carbamate-Functionized Spiro Compounds
- (2013) A. V. Velikorodov et al. PHARMACEUTICAL CHEMISTRY JOURNAL
- Recent Advances in Diversity Oriented Synthesis through Isatin-based Multicomponent Reactions
- (2013) Yunyun Liu et al. Asian Journal of Organic Chemistry
- Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks
- (2012) Girija S. Singh et al. CHEMICAL REVIEWS
- Recent advances in organocatalytic methods for the synthesis of disubstituted 2- and 3-indolinones
- (2012) Renato Dalpozzo et al. CHEMICAL SOCIETY REVIEWS
- Enantioselective Synthesis of Dihydropyrazoles by Formal [4+1] Cycloaddition of in Situ-Derived Azoalkenes and Sulfur Ylides
- (2012) Jia-Rong Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Strategies for the enantioselective synthesis of spirooxindoles
- (2012) Nicolas R. Ball-Jones et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Asymmetric Catalytic 1,3-Dipolar Cycloaddition Reaction of Nitrile Imines for the Synthesis of Chiral Spiro-Pyrazoline-Oxindoles
- (2012) Gang Wang et al. ORGANIC LETTERS
- Synthesis of Oxindolyl Pyrazolines and 3-Amino Oxindole Building Blocks via a Nitrile Imine [3 + 2] Cycloaddition Strategy
- (2012) Anand Singh et al. ORGANIC LETTERS
- Synthesis and Biological Activity of Chiral Dihydropyrazole: Potential Lead for Drug Design
- (2011) X.-H. Liu et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Synthetic and biological studies of pyrazolines and related heterocyclic compounds
- (2011) Mohamad Yusuf et al. Arabian Journal of Chemistry
- Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position
- (2010) Feng Zhou et al. ADVANCED SYNTHESIS & CATALYSIS
- Cultivating the Passion to Build Heterocycles from 1,2-Diaza-1,3-dienes: the Force of Imagination
- (2009) Orazio A. Attanasi et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started