Integration of pro- and anti-angiogenic signals by endothelial cells

Role of vascular normalization in benefit from metronomic chemotherapy

(2017) Fotios Mpekris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligand-induced growth and compaction of CD36 nanoclusters enriched in Fyn induces Fyn signaling

(2016) John Maringa Githaka et al.   JOURNAL OF CELL SCIENCE

Mechanisms and regulation of endothelial VEGF receptor signalling

(2016) Michael Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression

(2016) Jon-Vidar Gaustad et al.   Oncotarget

Combined therapy with thrombospondin-1 type I repeats (3TSR) and chemotherapy induces regression and significantly improves survival in a preclinical model of advanced stage epithelial ovarian cancer

(2015) Samantha Russell et al.   FASEB JOURNAL

Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis

(2014) A. Fantin et al.   DEVELOPMENT

Invoking the power of thrombospondins: Regulation of thrombospondins expression

(2014) Olga Stenina-Adognravi   MATRIX BIOLOGY

Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding

(2014) Maria V Gelfand et al.   eLife

The vascular permeabilizing factors histamine and serotonin induce angiogenesis through TR3/Nur77 and subsequently truncate it through thrombospondin-1

(2013) L. Qin et al.   BLOOD

Thrombospondin-1 modulates VEGF signaling via CD36 by recruiting SHP-1 to VEGFR2 complex in microvascular endothelial cells

(2013) L.-Y. Chu et al.   BLOOD

Thrombospondins

(2013) Olga Stenina-Adognravi   CURRENT OPINION IN LIPIDOLOGY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Molecular Basis for the Regulation of Angiogenesis by Thrombospondin-1 and -2

(2013) P. R. Lawler et al.   Cold Spring Harbor Perspectives in Medicine

VEGF signaling inside vascular endothelial cells and beyond

(2012) Anne Eichmann et al.   CURRENT OPINION IN CELL BIOLOGY

The matricellular protein thrombospondin-1 globally regulates cardiovascular function and responses to stress via CD47

(2012) David D. Roberts et al.   MATRIX BIOLOGY

Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanisms

(2012) Mariya T. Sweetwyne et al.   MATRIX BIOLOGY

Direct and Allosteric Inhibition of the FGF2/HSPGs/FGFR1 Ternary Complex Formation by an Antiangiogenic, Thrombospondin-1-Mimic Small Molecule

(2012) Katiuscia Pagano et al.   PLoS One

Priming of the vascular endothelial growth factor signaling pathway by thrombospondin-1, CD36, and spleen tyrosine kinase

(2011) S. Kazerounian et al.   BLOOD

CD47 applies the brakes to angiogenesis via vascular endothelial growth factor receptor-2

(2011) Sukhbir Kaur et al.   CELL CYCLE

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

(2011) Peter Carmeliet et al.   NATURE REVIEWS DRUG DISCOVERY

CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo

(2010) Manuel Koch et al.   BREAST CANCER RESEARCH AND TREATMENT

Molecular mechanisms underlying tumor dormancy

(2010) Nava Almog   CANCER LETTERS

Vessel abnormalization: another hallmark of cancer?Molecular mechanisms and therapeutic implications

(2010) Katrien De Bock et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Thrombospondin-1 Inhibits VEGF Receptor-2 Signaling by Disrupting Its Association with CD47

(2010) Sukhbir Kaur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-peptidic Thrombospondin-1 Mimics as Fibroblast Growth Factor-2 Inhibitors

(2010) Giorgio Colombo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombospondin-1 modulates VEGF-A-mediated Akt signaling and capillary survival in the developing retina

(2009) Jingfang Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A Double Hit to Kill Tumor and Endothelial Cells by TRAIL and Antiangiogenic 3TSR

(2009) B. Ren et al.   CANCER RESEARCH

CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior

(2009) R. L. Silverstein et al.   Science Signaling

Thrombospondins: from structure to therapeutics

(2008) S. Kazerounian et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Thrombospondins: from structure to therapeutics

(2008) C. B. Carlson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Fibroblast growth factor-2 binding to the thrombospondin-1 type III repeats, a novel antiangiogenic domain

(2007) Barbara Margosio et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Thrombospondins Use the VLDL Receptor and a Nonapoptotic Pathway to Inhibit Cell Division in Microvascular Endothelial Cells

(2007) Anush Oganesian et al.   MOLECULAR BIOLOGY OF THE CELL