Treatment strategies for autoimmune encephalitis

Intracellular and non-neuronal targets of voltage-gated potassium channel complex antibodies

(2017) Bethan Lang et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Autoantibodies to Synaptic Receptors and Neuronal Cell Surface Proteins in Autoimmune Diseases of the Central Nervous System

(2017) Josep Dalmau et al.   PHYSIOLOGICAL REVIEWS

Preservation of gonadal function in women undergoing chemotherapy: a review of the potential role for gonadotropin-releasing hormone agonists

(2016) Lisa C. Hickman et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Human cerebrospinal fluid monoclonalN-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis

(2016) Jakob Kreye et al.   BRAIN

Plasma exchange in pediatric anti-NMDAR encephalitis: A systematic review

(2016) Agnese Suppiej et al.   BRAIN & DEVELOPMENT

Cerebrospinal fluid markers of neuronal and glial cell damage to monitor disease activity and predict long-term outcome in patients with autoimmune encephalitis

(2016) R. Constantinescu et al.   EUROPEAN JOURNAL OF NEUROLOGY

Neuronal central nervous system syndromes probably mediated by autoantibodies

(2016) Aude Chefdeville et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Diagnosis and Treatment of Autoimmune Encephalitis

(2016) Eric Lancaster   Journal of Clinical Neurology

Prevalence of antineuronal antibodies in patients with encephalopathy of unknown etiology: Data from a nationwide registry in Korea

(2016) Jung-Ick Byun et al.   JOURNAL OF NEUROIMMUNOLOGY

New feasible treatment for refractory autoimmune encephalitis: Low-dose interleukin-2

(2016) Jung-Ah Lim et al.   JOURNAL OF NEUROIMMUNOLOGY

Immunoadsorption or plasma exchange in the treatment of autoimmune encephalitis: a pilot study

(2016) Josephine Heine et al.   JOURNAL OF NEUROLOGY

Cognitive and Social Functioning Deficits after Anti-N-Methyl-D-Aspartate Receptor Encephalitis: An Exploratory Case Series

(2016) Gemma L. McKeon et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Maintenance immunosuppression in myasthenia gravis

(2016) Lauren Gotterer et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A clinical approach to diagnosis of autoimmune encephalitis

(2016) Francesc Graus et al.   LANCET NEUROLOGY

Therapeutic approach to IgG4-related disease

(2016) Pilar Brito-Zerón et al.   MEDICINE

Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus

(2016) Jing He et al.   NATURE MEDICINE

Plasma cells as an innovative target in autoimmune disease with renal manifestations

(2016) Falk Hiepe et al.   Nature Reviews Nephrology

Autoimmune synaptopathies

(2016) Sarah J. Crisp et al.   NATURE REVIEWS NEUROSCIENCE

Rituximab treatment for autoimmune limbic encephalitis in an institutional cohort

(2016) Woo-Jin Lee et al.   NEUROLOGY

Bortezomib for treatment of therapy-refractory anti-NMDA receptor encephalitis

(2016) Franziska Scheibe et al.   NEUROLOGY

Anti-LGI1–associated cognitive impairment

(2016) Helena Ariño et al.   NEUROLOGY

The clinical spectrum of Caspr2 antibody–associated disease

(2016) Agnes van Sonderen et al.   NEUROLOGY

Anti-LGI1 encephalitis

(2016) Agnes van Sonderen et al.   NEUROLOGY

The relevance of VGKC positivity in the absence of LGI1 and Caspr2 antibodies

(2016) Agnes van Sonderen et al.   NEUROLOGY

Tocilizumab in Autoimmune Encephalitis Refractory to Rituximab: An Institutional Cohort Study

(2016) Woo-Jin Lee et al.   Neurotherapeutics

Utility of CSF Cytokine/Chemokines as Markers of Active Intrathecal Inflammation: Comparison of Demyelinating, Anti-NMDAR and Enteroviral Encephalitis

(2016) Kavitha Kothur et al.   PLoS One

Effect of Immunotherapy on Seizure Outcome in Patients with Autoimmune Encephalitis: A Prospective Observational Registry Study

(2016) Jung-Ick Byun et al.   PLoS One

I mmuno g lobuli N i n the T reatment of E ncephalitis (IgNiTE): protocol for a multicentre randomised controlled trial

(2016) M A Iro et al.   BMJ Open

Bortezomib Treatment for Patients With Anti-N-Methyl-d-Aspartate Receptor Encephalitis

(2016) Volker Behrendt et al.   JAMA Neurology

Efficacy and Safety of Rituximab Therapy in Neuromyelitis Optica Spectrum Disorders

(2016) Valentina Damato et al.   JAMA Neurology

Association of Progressive Cerebellar Atrophy With Long-term Outcome in Patients With Anti-N-Methyl-d-Aspartate Receptor Encephalitis

(2016) Takahiro Iizuka et al.   JAMA Neurology

Clinical and Immunologic Investigations in Patients With Stiff-Person Spectrum Disorder

(2016) Eugenia Martinez-Hernandez et al.   JAMA Neurology

Chronic Stress and Glucocorticoids: From Neuronal Plasticity to Neurodegeneration

(2016) Sheela Vyas et al.   NEURAL PLASTICITY

Detection and Characterization of Autoantibodies to Neuronal Cell-Surface Antigens in the Central Nervous System

(2016) Marleen H. van Coevorden-Hameete et al.   Frontiers in Molecular Neuroscience

Transient spurious intrathecal immunoglobulin synthesis in neurological patients after therapeutic apheresis

(2015) Benjamin Berger et al.   BMC Neurology

Epileptogenic effects of NMDAR antibodies in a passive transfer mouse model

(2015) Sukhvir Wright et al.   BRAIN

Interleukin-6 as a Therapeutic Target

(2015) J.-F. Rossi et al.   CLINICAL CANCER RESEARCH

Immunosuppressive Medications

(2015) A. C. Wiseman   Clinical Journal of the American Society of Nephrology

Selective IL-2 Responsiveness of Regulatory T Cells Through Multiple Intrinsic Mechanisms Supports the Use of Low-Dose IL-2 Therapy in Type 1 Diabetes

(2015) Aixin Yu et al.   DIABETES

The expanding field of IgG4-mediated neurological autoimmune disorders

(2015) M. G. Huijbers et al.   EUROPEAN JOURNAL OF NEUROLOGY

Immune therapy in autoimmune encephalitis: a systematic review

(2015) Margherita Nosadini et al.   Expert Review of Neurotherapeutics

Intravenous methylprednisolone versus therapeutic plasma exchange for treatment of anti-n-methyl-d-aspartate receptor antibody encephalitis: A retrospective review

(2015) Allen D. DeSena et al.   JOURNAL OF CLINICAL APHERESIS

Encephalitis and AMPA receptor antibodies: Novel findings in a case series of 22 patients

(2015) R. Hoftberger et al.   NEUROLOGY

Antibodies to GABAA receptor  1 and  2 subunits: Clinical and serologic characterization

(2015) P. Pettingill et al.   NEUROLOGY

CSF findings in patients with anti-N-methyl-d-aspartate receptor-encephalitis

(2015) Rui Wang et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Immune therapy in autoimmune encephalitis: a systematic review

(2015) Margherita Nosadini et al.   Expert Review of Neurotherapeutics

Investigations on CXCL13 in Anti–N-Methyl-D-Aspartate Receptor Encephalitis

(2015) Frank Leypoldt et al.   JAMA Neurology

Severe Cognitive Impairment Associated With Intrathecal Antibodies to the NR1 Subunit of theN-Methyl-D-Aspartate Receptor in a Patient With Multiple Sclerosis

(2015) Robert Fleischmann et al.   JAMA Neurology

Paraneoplastic Neurological Syndromes and Glutamic Acid Decarboxylase Antibodies

(2015) Helena Ariño et al.   JAMA Neurology

Long-term Therapy With Interleukin 6 Receptor Blockade in Highly Active Neuromyelitis Optica Spectrum Disorder

(2015) Marius Ringelstein et al.   JAMA Neurology

Hepatitis B Reactivation and Rituximab: A New Boxed Warning and Considerations for Solid Organ Transplantation

(2014) S. T. Martin et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Overlapping demyelinating syndromes and anti-N-methyl-D-aspartate receptor encephalitis

(2014) Maarten J. Titulaer et al.   ANNALS OF NEUROLOGY

Acute mechanisms underlying antibody effects in anti-N-methyl-D-aspartate receptor encephalitis

(2014) Emilia H. Moscato et al.   ANNALS OF NEUROLOGY

Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes

(2014) Alexander Carvajal-González et al.   BRAIN

Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

(2014) Jesús Planagumà et al.   BRAIN

Tryptophan immunoadsorption for the treatment of autoimmune encephalitis

(2014) W. Köhler et al.   EUROPEAN JOURNAL OF NEUROLOGY

Therapeutic uses of anti-interleukin-6 receptor antibody

(2014) S. Kang et al.   INTERNATIONAL IMMUNOLOGY

Outcome of limbic encephalitis with VGKC-complex antibodies: relation to antigenic specificity

(2014) M. P. Malter et al.   JOURNAL OF NEUROLOGY

Natural course of LGI1 encephalitis: 3–5years of follow-up without immunotherapy

(2014) Monika Szots et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAA receptor: a case series, characterisation of the antigen, and analysis of the effects of antibodies

(2014) Mar Petit-Pedrol et al.   LANCET NEUROLOGY

A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series, characterisation of the antigen, and post-mortem study

(2014) Lidia Sabater et al.   LANCET NEUROLOGY

Treatment of neuromyelitis optica: state-of-the-art and emerging therapies

(2014) Marios C. Papadopoulos et al.   Nature Reviews Neurology

Utility and safety of rituximab in pediatric autoimmune and inflammatory CNS disease

(2014) R. C. Dale et al.   NEUROLOGY

DPPX potassium channel antibody: Frequency, clinical accompaniments, and outcomes in 20 patients

(2014) W. O. Tobin et al.   NEUROLOGY

Efficacy of the anti-IL-6 receptor antibody tocilizumab in neuromyelitis optica: A pilot study

(2014) M. Araki et al.   NEUROLOGY

Effects of Low-Dose Recombinant Interleukin 2 to Promote T-Regulatory Cells in Alopecia Areata

(2014) Emeline Castela et al.   JAMA Dermatology

The mechanisms of action of plasma exchange

(2013) Hollie M. Reeves et al.   BRITISH JOURNAL OF HAEMATOLOGY

Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy

(2013) Wei Liao et al.   IMMUNITY

Autoimmune encephalitis: Recent updates and emerging challenges

(2013) Sudarshini Ramanathan et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Rituximab ameliorates anti-N-methyl-d-aspartate receptor encephalitis by removal of short-lived plasmablasts

(2013) Yasuo Hachiya et al.   JOURNAL OF NEUROIMMUNOLOGY

Prevalence and treatment of anti-NMDA receptor encephalitis – Authors' reply

(2013) Maarten J Titulaer et al.   LANCET NEUROLOGY

Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study

(2013) Maarten J Titulaer et al.   LANCET NEUROLOGY

Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study

(2013) Nuria Gresa-Arribas et al.   LANCET NEUROLOGY

Regulatory T cell proliferative potential is impaired in human autoimmune disease

(2013) Fortunata Carbone et al.   NATURE MEDICINE

Encephalitis and GABAB receptor antibodies: Novel findings in a new case series of 20 patients

(2013) R. Hoftberger et al.   NEUROLOGY

Persistent Intrathecal Antibody Synthesis 15 Years After Recovering From Anti– N-methyl-D-aspartate Receptor Encephalitis

(2013) Hans-Christian Hansen et al.   JAMA Neurology

Interleukin 6 Receptor Blockade in Patients With Neuromyelitis Optica Nonresponsive to Anti-CD20 Therapy

(2013) Ilya Ayzenberg et al.   JAMA Neurology

Successful Treatment of Anti-Caspr2 Syndrome by Interleukin 6 Receptor Blockade Through Tocilizumab

(2013) Christos Krogias et al.   JAMA Neurology

A 5-Year Follow-up of Rituximab Treatment in Patients With Neuromyelitis Optica Spectrum Disorder

(2013) Su-Hyun Kim et al.   JAMA Neurology

A case of anti-N-methyl-d-aspartate receptor encephalitis with multiple sclerosis-like demyelinated lesions

(2013) Akitoshi Takeda et al.   Multiple Sclerosis and Related Disorders

Encephalitis and antibodies to dipeptidyl-peptidase-like protein-6, a subunit of Kv4.2 potassium channels

(2012) Anna Boronat et al.   ANNALS OF NEUROLOGY

Morvan syndrome: Clinical and serological observations in 29 cases

(2012) Sarosh R. Irani et al.   ANNALS OF NEUROLOGY

Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis

(2012) C. G. Bien et al.   BRAIN

Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis

(2012) Lenka Mikasova et al.   BRAIN

The Frequency of Autoimmune N-Methyl-D-Aspartate Receptor Encephalitis Surpasses That of Individual Viral Etiologies in Young Individuals Enrolled in the California Encephalitis Project

(2012) M. S. Gable et al.   CLINICAL INFECTIOUS DISEASES

CXCL13 is the major determinant for B cell recruitment to the CSF during neuroinflammation

(2012) Markus C Kowarik et al.   Journal of Neuroinflammation

Paraneoplastic and non-paraneoplastic autoimmunity to neurons in the central nervous system

(2012) Nico Melzer et al.   JOURNAL OF NEUROLOGY

Anti-NMDA Receptor Encephalitis Antibody Binding Is Dependent on Amino Acid Identity of a Small Region within the GluN1 Amino Terminal Domain

(2012) A. J. Gleichman et al.   JOURNAL OF NEUROSCIENCE

Re-establishing immunological self-tolerance in autoimmune disease

(2012) Shimon Sakaguchi et al.   NATURE MEDICINE

Intravenous Immune Globulin in Autoimmune and Inflammatory Diseases

(2012) Erwin W. Gelfand   NEW ENGLAND JOURNAL OF MEDICINE

Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis

(2012) Fabrizio De Benedetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Repeated Treatment With Rituximab Based on the Assessment of Peripheral Circulating Memory B Cells in Patients With Relapsing Neuromyelitis Optica Over 2 Years

(2011) Su-Hyun Kim   ARCHIVES OF NEUROLOGY

Anti-N-methyl d-aspartate-type glutamate receptor antibody-positive limbic encephalitis in a patient with multiple sclerosis

(2011) Akiyuki Uzawa et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Cognitive deficits following anti-NMDA receptor encephalitis

(2011) Carsten Finke et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Encephalitis and antibodies to synaptic and neuronal cell surface proteins

(2011) E. Lancaster et al.   NEUROLOGY

Analysis of relapses in anti-NMDAR encephalitis

(2011) I. Gabilondo et al.   NEUROLOGY

Analysis of complement and plasma cells in the brain of patients with anti-NMDAR encephalitis

(2011) E. Martinez-Hernandez et al.   NEUROLOGY

Regulatory T-Cell Responses to Low-Dose Interleukin-2 in HCV-Induced Vasculitis

(2011) David Saadoun et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease

(2011) John Koreth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Investigations of caspr2, an autoantigen of encephalitis and neuromyotonia

(2010) Eric Lancaster et al.   ANNALS OF NEUROLOGY

N-methyl-d-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes

(2010) Sarosh R. Irani et al.   BRAIN

Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity

(2010) Thomas R. Malek et al.   IMMUNITY

Reversible brain atrophy in anti-NMDA receptor encephalitis: a long-term observational study

(2010) Takahiro Iizuka et al.   JOURNAL OF NEUROLOGY

Cellular and Synaptic Mechanisms of Anti-NMDA Receptor Encephalitis

(2010) E. G. Hughes et al.   JOURNAL OF NEUROSCIENCE

Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series

(2010) Meizan Lai et al.   LANCET NEUROLOGY

Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis

(2010) Josep Dalmau et al.   LANCET NEUROLOGY

NMDA RECEPTOR ENCEPHALITIS MIMICKING SERONEGATIVE NEUROMYELITIS OPTICA

(2010) M. C. Kruer et al.   NEUROLOGY

Practical considerations on the use of rituximab in autoimmune neurological disorders

(2010) Mixalis L. Kosmidis et al.   Therapeutic Advances in Neurological Disorders

Evidence for antibody-mediated pathogenesis in anti-NMDAR encephalitis associated with ovarian teratoma

(2009) Erdem Tüzün et al.   ACTA NEUROPATHOLOGICA

AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location

(2009) Meizan Lai et al.   ANNALS OF NEUROLOGY

Antibodies to glutamic acid decarboxylase define a form of limbic encephalitis

(2009) Michael P. Malter et al.   ANNALS OF NEUROLOGY

Plasma exchange and immunoadsorption for autoimmune neurologic diseases – current guidelines and future perspectives

(2009) Reinhard Klingel et al.   ATHEROSCLEROSIS SUPPLEMENTS

Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project

(2009) K. R. Carson et al.   BLOOD

Current Proposed Mechanisms of Action of Intravenous Immunoglobulins in Inflammatory Neuropathies

(2009) Saiju Jacob et al.   Current Neuropharmacology

A Low Interleukin-2 Receptor Signaling Threshold Supports the Development and Homeostasis of T Regulatory Cells

(2009) Aixin Yu et al.   IMMUNITY

Antibodies to the GABAB receptor in limbic encephalitis with seizures: case series and characterisation of the antigen

(2009) Eric Lancaster et al.   LANCET NEUROLOGY

GAD65 as a prototypic autoantigen

(2008) Gustavo Fenalti et al.   JOURNAL OF AUTOIMMUNITY

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial

(2008) Josef S Smolen et al.   LANCET

Paraneoplastic syndromes of the CNS

(2008) Josep Dalmau et al.   LANCET NEUROLOGY

Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies

(2008) Josep Dalmau et al.   LANCET NEUROLOGY

PROGRESSIVE ENCEPHALOMYELITIS, RIGIDITY, AND MYOCLONUS: A NOVEL GLYCINE RECEPTOR ANTIBODY

(2008) M. Hutchinson et al.   NEUROLOGY

Invited Article: Inhibition of B cell functions: Implications for neurology

(2008) M. C. Dalakas   NEUROLOGY

How corticosteroids control inflammation: Quintiles Prize Lecture 2005

(2006) Peter J Barnes   BRITISH JOURNAL OF PHARMACOLOGY