Autoimmune synaptopathies

Cellular plasticity induced by anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor encephalitis antibodies

(2015) Xiaoyu Peng et al.   ANNALS OF NEUROLOGY

Epileptogenic effects of NMDAR antibodies in a passive transfer mouse model

(2015) Sukhvir Wright et al.   BRAIN

Ketamine and phencyclidine: the good, the bad and the unexpected

(2015) D Lodge et al.   BRITISH JOURNAL OF PHARMACOLOGY

GRIN1mutations cause encephalopathy with infantile-onset epilepsy, and hyperkinetic and stereotyped movement disorders

(2015) Chihiro Ohba et al.   EPILEPSIA

Electrophysiological analysis of neuromuscular synaptic function in myasthenia gravis patients and animal models

(2015) Jaap J. Plomp et al.   EXPERIMENTAL NEUROLOGY

Human IgG4: a structural perspective

(2015) Anna M. Davies et al.   IMMUNOLOGICAL REVIEWS

MuSK Frizzled-Like Domain Is Critical for Mammalian Neuromuscular Junction Formation and Maintenance

(2015) J. Messeant et al.   JOURNAL OF NEUROSCIENCE

Lambert-Eaton syndrome IgG inhibits transmitter release via P/Q Ca2+ channels

(2015) J. Spillane et al.   NEUROLOGY

Encephalitis and AMPA receptor antibodies: Novel findings in a case series of 22 patients

(2015) R. Hoftberger et al.   NEUROLOGY

Anti-DPPX encephalitis

(2015) Johannes Piepgras et al.   NEUROLOGY

Antibodies to GABAA receptor  1 and  2 subunits: Clinical and serologic characterization

(2015) P. Pettingill et al.   NEUROLOGY

Targeted Ablation, Silencing, and Activation Establish Glycinergic Dorsal Horn Neurons as Key Components of a Spinal Gate for Pain and Itch

(2015) Edmund Foster et al.   NEURON

Preexisting Serum Autoantibodies Against the NMDAR Subunit NR1 Modulate Evolution of Lesion Size in Acute Ischemic Stroke

(2015) M. Zerche et al.   STROKE

Control of cortical neuronal migration by glutamate and GABA

(2015) Heiko J. Luhmann et al.   Frontiers in Cellular Neuroscience

Clinical Spectrum of Encephalitis Associated With Antibodies Against the α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor

(2015) Bastien Joubert et al.   JAMA Neurology

Absence ofN-Methyl-D-Aspartate Receptor IgG Autoantibodies in Schizophrenia

(2015) Lot D. de Witte et al.   JAMA Psychiatry

Acute mechanisms underlying antibody effects in anti-N-methyl-D-aspartate receptor encephalitis

(2014) Emilia H. Moscato et al.   ANNALS OF NEUROLOGY

Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes

(2014) Alexander Carvajal-González et al.   BRAIN

Glutamatergic neuron-targeted loss of LGI1 epilepsy gene results in seizures

(2014) Morgane Boillot et al.   BRAIN

Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

(2014) Jesús Planagumà et al.   BRAIN

Homozygous Deletion of the LGI1 Gene in Mice Leads to Developmental Abnormalities Resulting in Cortical Dysplasia

(2014) Jeane Silva et al.   BRAIN PATHOLOGY

Clinical and scientific aspects of muscle-specific tyrosine kinase-related myasthenia gravis

(2014) Stephen W. Reddel et al.   CURRENT OPINION IN NEUROLOGY

Seroprevalence of n-methyl-d-aspartate glutamate receptor (NMDA-R) autoantibodies in aging subjects without neuropsychiatric disorders and in dementia patients

(2014) Stefan Busse et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Myasthenia gravis: A comprehensive review of immune dysregulation and etiological mechanisms

(2014) Sonia Berrih-Aknin et al.   JOURNAL OF AUTOIMMUNITY

Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing

(2014) Claire Redin et al.   JOURNAL OF MEDICAL GENETICS

Outcome of limbic encephalitis with VGKC-complex antibodies: relation to antigenic specificity

(2014) M. P. Malter et al.   JOURNAL OF NEUROLOGY

Limbic encephalitis due to GABABand AMPA receptor antibodies: a case series

(2014) M Dogan Onugoren et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Persistent anterograde amnesia following limbic encephalitis associated with antibodies to the voltage-gated potassium channel complex

(2014) C. R. Butler et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

IgG and Complement Deposition and Neuronal Loss in Cats and Humans With Epilepsy and Voltage-Gated Potassium Channel Complex Antibodies

(2014) Andrea Klang et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

LRP4 Is Critical for Neuromuscular Junction Maintenance

(2014) A. Barik et al.   JOURNAL OF NEUROSCIENCE

Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAA receptor: a case series, characterisation of the antigen, and analysis of the effects of antibodies

(2014) Mar Petit-Pedrol et al.   LANCET NEUROLOGY

A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series, characterisation of the antigen, and post-mortem study

(2014) Lidia Sabater et al.   LANCET NEUROLOGY

Progressive encephalomyelitis with rigidity and myoclonus: A new variant with DPPX antibodies

(2014) B. Balint et al.   NEUROLOGY

N-methyl-d-aspartate glutamate receptor (NMDA-R) antibodies in mild cognitive impairment and dementias

(2014) Stefan Busse et al.   NEUROSCIENCE RESEARCH

Immunotherapy for patients with acute psychosis and serum N-Methyl d-Aspartate receptor (NMDAR) antibodies: A description of a treated case series

(2014) Michael S. Zandi et al.   SCHIZOPHRENIA RESEARCH

Abnormal Neurons in Teratomas in NMDAR Encephalitis

(2014) Gregory S. Day et al.   JAMA Neurology

IgG Subclasses and Allotypes: From Structure to Effector Functions

(2014) Gestur Vidarsson et al.   Frontiers in Immunology

High prevalence of NMDA receptor IgA/IgM antibodies in different dementia types

(2014) Sarah Doss et al.   Annals of Clinical and Translational Neurology

Herpes simplex virus encephalitis is a trigger of brain autoimmunity

(2013) Thaís Armangue et al.   ANNALS OF NEUROLOGY

Complement associated pathogenic mechanisms in myasthenia gravis

(2013) Erdem Tüzün et al.   AUTOIMMUNITY REVIEWS

Postnatal development of glycine receptor subunits α1, α2, α3, and β immunoreactivity in multiple brain stem respiratory-related nuclear groups of the rat

(2013) Qiuli Liu et al.   BRAIN RESEARCH

Prevalence of neurologic autoantibodies in cohorts of patients with new and established epilepsy

(2013) Tanja Brenner et al.   EPILEPSIA

Autoimmune epilepsy in children: Case series and proposed guidelines for identification

(2013) Jehan Suleiman et al.   EPILEPSIA

Shining a light on CNTNAP2: complex functions to complex disorders

(2013) Pedro Rodenas-Cuadrado et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Faciobrachial dystonic seizures arise from cortico–subcortical abnormal brain areas

(2013) Frank Boesebeck et al.   JOURNAL OF NEUROLOGY

Autoantibodies to Epilepsy-Related LGI1 in Limbic Encephalitis Neutralize LGI1-ADAM22 Interaction and Reduce Synaptic AMPA Receptors

(2013) T. Ohkawa et al.   JOURNAL OF NEUROSCIENCE

Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study

(2013) Maarten J Titulaer et al.   LANCET NEUROLOGY

Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood–brain barrier integrity

(2013) C Hammer et al.   MOLECULAR PSYCHIATRY

N-methyl-D-aspartate receptor antibodies in post-herpes simplex virus encephalitis neurological relapse

(2013) Yael Hacohen et al.   MOVEMENT DISORDERS

Herpes simplex encephalitis relapse with chorea is associated with autoantibodies toN-Methyl-D-aspartate receptor or dopamine-2 receptor

(2013) Shekeeb S. Mohammad et al.   MOVEMENT DISORDERS

A randomized, double-blind, placebo-controlled phase II study of eculizumab in patients with refractory generalized myasthenia gravis

(2013) James F. Howard et al.   MUSCLE & NERVE

De novo mutations in epileptic encephalopathies

(2013) et al.   NATURE

Teaching NeuroImages: Basal ganglia involvement in facio-brachial dystonic seizures associated with LGI1 antibodies

(2013) D. Plantone et al.   NEUROLOGY

Encephalitis and GABAB receptor antibodies: Novel findings in a new case series of 20 patients

(2013) R. Hoftberger et al.   NEUROLOGY

MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4

(2013) M. G. Huijbers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequency and Characteristics of Isolated Psychiatric Episodes in Anti–N-Methyl-d-Aspartate Receptor Encephalitis

(2013) Matthew S. Kayser et al.   JAMA Neurology

Increased Prevalence of Diverse N -Methyl-D-Aspartate Glutamate Receptor Antibodies in Patients With an Initial Diagnosis of Schizophrenia

(2013) Johann Steiner et al.   JAMA Psychiatry

Encephalitis and antibodies to dipeptidyl-peptidase-like protein-6, a subunit of Kv4.2 potassium channels

(2012) Anna Boronat et al.   ANNALS OF NEUROLOGY

Morvan syndrome: Clinical and serological observations in 29 cases

(2012) Sarosh R. Irani et al.   ANNALS OF NEUROLOGY

Transport activities and expression patterns of glycine transporters 1 and 2 in the developing murine brain stem and spinal cord

(2012) Deepti Lall et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice

(2012) Rinse Klooster et al.   BRAIN

Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis

(2012) C. G. Bien et al.   BRAIN

Antibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders

(2012) Russell C. Dale et al.   BRAIN

Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis

(2012) Lenka Mikasova et al.   BRAIN

Changes in glycine receptor subunit expression in forebrain regions of the Wistar rat over development

(2012) Susanne Jonsson et al.   BRAIN RESEARCH

The startle syndromes: Physiology and treatment

(2012) Yasmine E. M. Dreissen et al.   EPILEPSIA

Passive and active immunization models of MuSK-Ab positive myasthenia: Electrophysiological evidence for pre and postsynaptic defects

(2012) Stuart Viegas et al.   EXPERIMENTAL NEUROLOGY

Pathogenic and physiological autoantibodies in the central nervous system

(2012) Maike Gold et al.   IMMUNOLOGICAL REVIEWS

Anti-NMDA Receptor Encephalitis Antibody Binding Is Dependent on Amino Acid Identity of a Small Region within the GluN1 Amino Terminal Domain

(2012) A. J. Gleichman et al.   JOURNAL OF NEUROSCIENCE

Epilepsy Gene LGI1 Regulates Postnatal Developmental Remodeling of Retinogeniculate Synapses

(2012) Y.-D. Zhou et al.   JOURNAL OF NEUROSCIENCE

Stoichiometry of the Human Glycine Receptor Revealed by Direct Subunit Counting

(2012) N. Durisic et al.   JOURNAL OF NEUROSCIENCE

Pediatric Anti-N-methyl-D-Aspartate Receptor Encephalitis—Clinical Analysis and Novel Findings in a Series of 20 Patients

(2012) Thaís Armangue et al.   JOURNAL OF PEDIATRICS

Supranuclear gaze palsy in glycine receptor antibody-positive progressive encephalomyelitis with rigidity and myoclonus

(2012) Elke Peeters et al.   MOVEMENT DISORDERS

Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses

(2012) Norihiro Yumoto et al.   NATURE

An anatomically comprehensive atlas of the adult human brain transcriptome

(2012) Michael J. Hawrylycz et al.   NATURE

Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development

(2012) G. R. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibodies against Muscle-Specific Kinase Impair Both Presynaptic and Postsynaptic Functions in a Murine Model of Myasthenia Gravis

(2011) Shuuichi Mori et al.   AMERICAN JOURNAL OF PATHOLOGY

Absence of CNTNAP2 Leads to Epilepsy, Neuronal Migration Abnormalities, and Core Autism-Related Deficits

(2011) Olga Peñagarikano et al.   CELL

A case of glycine-receptor antibody-associated encephalomyelitis with rigidity and myoclonus (PERM): clinical course, treatment and CSF findings

(2011) A. Piotrowicz et al.   JOURNAL OF NEUROLOGY

Cognitive deficits following anti-NMDA receptor encephalitis

(2011) Carsten Finke et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

EphB Controls NMDA Receptor Function and Synaptic Targeting in a Subunit-Specific Manner

(2011) M. J. Nolt et al.   JOURNAL OF NEUROSCIENCE

Suppression of synaptic plasticity by cerebrospinal fluid from anti-NMDA receptor encephalitis patients

(2011) Qing Zhang et al.   NEUROBIOLOGY OF DISEASE

Progressive encephalomyelitis with rigidity and myoclonus: Resolution after thymectomy

(2011) K. Clerinx et al.   NEUROLOGY

Antibodies to metabotropic glutamate receptor 5 in the Ophelia syndrome

(2011) E. Lancaster et al.   NEUROLOGY

In vivo effects of antibodies from patients with anti-NMDA receptor encephalitis: further evidence of synaptic glutamatergic dysfunction

(2011) Mario Manto et al.   Orphanet Journal of Rare Diseases

Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis

(2010) Osamu Higuchi et al.   ANNALS OF NEUROLOGY

Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis

(2010) Sarosh R. Irani et al.   ANNALS OF NEUROLOGY

Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice

(2010) Elodie Chabrol et al.   BRAIN

N-methyl-d-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes

(2010) Sarosh R. Irani et al.   BRAIN

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia

(2010) Sarosh R. Irani et al.   BRAIN

Human limbic encephalitis serum enhances hippocampal mossy fiber-CA3 pyramidal cell synaptic transmission

(2010) Tatjana Lalic et al.   EPILEPSIA

Structure and function of immunoglobulins

(2010) Harry W. Schroeder et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Afferent facilitation of corticomotor responses is increased by IgGs of patients with NMDA-receptor antibodies

(2010) Mario Manto et al.   JOURNAL OF NEUROLOGY

Cellular and Synaptic Mechanisms of Anti-NMDA Receptor Encephalitis

(2010) E. G. Hughes et al.   JOURNAL OF NEUROSCIENCE

Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series

(2010) Meizan Lai et al.   LANCET NEUROLOGY

Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis

(2010) Josep Dalmau et al.   LANCET NEUROLOGY

Disruption of LGI1–linked synaptic complex causes abnormal synaptic transmission and epilepsy

(2010) Yuko Fukata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for antibody-mediated pathogenesis in anti-NMDAR encephalitis associated with ovarian teratoma

(2009) Erdem Tüzün et al.   ACTA NEUROPATHOLOGICA

AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location

(2009) Meizan Lai et al.   ANNALS OF NEUROLOGY

Differential localization of γ-aminobutyric acid type a and glycine receptor subunits and gephyrin in the human pons, medulla oblongata and uppermost cervical segment of the spinal cord: An immunohistochemical study

(2009) H.J. Waldvogel et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Role of Glycinergic Inhibition in Shaping Activity of Saccadic Burst Neurons

(2009) Yoshiki Iwamoto et al.   JOURNAL OF NEUROPHYSIOLOGY

Antibodies to the GABAB receptor in limbic encephalitis with seizures: case series and characterisation of the antigen

(2009) Eric Lancaster et al.   LANCET NEUROLOGY

LGI1-associated epilepsy through altered ADAM23-dependent neuronal morphology

(2009) Katherine Owuor et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

IgG1 antibodies to acetylcholine receptors in ‘seronegative’ myasthenia gravis†

(2008) Maria Isabel Leite et al.   BRAIN

Lrp4 Is a Receptor for Agrin and Forms a Complex with MuSK

(2008) Natalie Kim et al.   CELL

Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies

(2008) Josep Dalmau et al.   LANCET NEUROLOGY

Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupus

(2008) Ji Y Lee et al.   NATURE MEDICINE

LRP4 Serves as a Coreceptor of Agrin

(2008) Bin Zhang et al.   NEURON

Regulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity

(2008) Koji Yashiro et al.   NEUROPHARMACOLOGY

Native glycine receptor subtypes and their physiological roles

(2008) Joseph W. Lynch   NEUROPHARMACOLOGY

GABAA receptors: Subtypes provide diversity of function and pharmacology

(2008) Richard W. Olsen et al.   NEUROPHARMACOLOGY