Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth

Degradation of mutant p53H175 protein by Zn(II) through autophagy

(2014) A Garufi et al.   Cell Death & Disease

Dissecting the pathways that destabilize mutant p53: The proteasome or autophagy?

(2013) Sujata Choundhury et al.   CELL CYCLE

Allele-Specific p53 Mutant Reactivation

(2012) Xin Yu et al.   CANCER CELL

Mutant p53: one name, many proteins

(2012) W. A. Freed-Pastor et al.   GENES & DEVELOPMENT

Selective Depletion of Mutant p53 by Cancer Chemopreventive Isothiocyanates and Their Structure−Activity Relationships

(2011) Xiantao Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair

(2011) Lisa Woodbine et al.   NUCLEIC ACIDS RESEARCH

Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress

(2011) M. Aggarwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenethyl Isothiocyanate Inhibits Oxidative Phosphorylation to Trigger Reactive Oxygen Species-mediated Death of Human Prostate Cancer Cells

(2010) Dong Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of SATB1 in Breast Cancer Pathogenesis

(2010) Elizabeth Iorns et al.   JNCI-Journal of the National Cancer Institute

Intracellular signaling and hepatocellular carcinoma

(2010) Polina Iakova et al.   SEMINARS IN CANCER BIOLOGY

Atg5 Regulates Phenethyl Isothiocyanate-Induced Autophagic and Apoptotic Cell Death in Human Prostate Cancer Cells

(2009) A. Bommareddy et al.   CANCER RESEARCH

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

Cancer Preventive Isothiocyanates Induce Selective Degradation of Cellular α- and β-Tubulins by Proteasomes

(2009) Lixin Mi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A common gain of function of p53 cancer mutants in inducing genetic instability

(2009) D P Liu et al.   ONCOGENE