Elevated Levels of Peripheral Kynurenine Decrease Bone Strength in Rats with Chronic Kidney Disease

Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss

(2017) Mona El Refaey et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A link between central kynurenine metabolism and bone strength in rats with chronic kidney disease

(2017) Bartlomiej Kalaska et al.   PeerJ

Moderate chronic kidney disease impairs bone quality in C57Bl/6J mice

(2016) Chelsea M. Heveran et al.   BONE

The Nuclear Receptor AhR Controls Bone Homeostasis by Regulating Osteoclast Differentiation via the RANK/c-Fos Signaling Axis

(2016) Takashi Izawa et al.   JOURNAL OF IMMUNOLOGY

Serum metabolic fingerprinting after exposure of rats to quinolinic acid

(2016) Bartlomiej Kalaska et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The Association between Elevated Levels of Peripheral Serotonin and Its Metabolite – 5-Hydroxyindoleacetic Acid and Bone Strength and Metabolism in Growing Rats with Mild Experimental Chronic Kidney Disease

(2016) Dariusz Pawlak et al.   PLoS One

Urinary Sodium and Potassium Excretion and CKD Progression

(2015) J. He et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Oxidation of the aromatic amino acids tryptophan and tyrosine disrupts their anabolic effects on bone marrow mesenchymal stem cells

(2015) Mona El Refaey et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Bone remodeling markers: so easy to measure, so difficult to interpret

(2015) E. Seeman et al.   OSTEOPOROSIS INTERNATIONAL

Aryl Hydrocarbon Receptors in Osteoclast Lineage Cells Are a Negative Regulator of Bone Mass

(2015) Tai-yong Yu et al.   PLoS One

Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study

(2014) E. M. Apalset et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The three-year incidence of fracture in chronic kidney disease

(2014) Kyla L. Naylor et al.   KIDNEY INTERNATIONAL

The Associations of Serum Serotonin with Bone Traits Are Age- and Gender-Specific

(2014) Qin Wang et al.   PLoS One

The Kynurenine Pathway of Tryptophan Degradation is Activated During Osteoblastogenesis

(2014) Christopher Vidal et al.   STEM CELLS

Metabolomics in chronic kidney disease

(2013) Ying-Yong Zhao   CLINICA CHIMICA ACTA

The G60S connexin 43 mutation activates the osteoblast lineage and results in a resorption-stimulating bone matrix and abrogation of old-age-related bone loss

(2013) Tanya Zappitelli et al.   JOURNAL OF BONE AND MINERAL RESEARCH

New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties

(2013) Maria Herlin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The influence of follistatin on mechanical properties of bone tissue in growing mice with overexpression of follistatin

(2012) Anna Gajos-Michniewicz et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Topically administered Risedronate shows powerful anti-osteoporosis effect in ovariectomized mouse model

(2011) So Hee Nam et al.   BONE

Vitamin K2 Improves Renal Function and Increases Femoral Bone Strength in Rats with Renal Insufficiency

(2011) Jun Iwamoto et al.   CALCIFIED TISSUE INTERNATIONAL

5-HT and bone biology

(2011) Patricia Ducy   CURRENT OPINION IN PHARMACOLOGY

Increased Numbers of Nonattached Osteoclasts After Long-Term Zoledronic Acid Therapy in Mice

(2011) Shinichiro Kuroshima et al.   ENDOCRINOLOGY

A comparison between micro-CT and histology for the evaluation of cortical bone: effect of polymethylmethacrylate embedding on structural parameters

(2011) F. PARTICELLI et al.   JOURNAL OF MICROSCOPY

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

Mineral and bone disorders in children with chronic kidney disease

(2011) Claus Peter Schmitt et al.   Nature Reviews Nephrology

Methods for Assessing Bone Quality: A Review

(2010) Eve Donnelly   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

The effects of ovariectomy and 17β-estradiol on cortical bone histomorphometry in growing rats

(2010) Russell T. Turner et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Continuous elevation of PTH increases the number of osteoblasts via both osteoclast-dependent and -independent mechanisms

(2010) Robert L Jilka et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The two faces of serotonin in bone biology

(2010) Patricia Ducy et al.   JOURNAL OF CELL BIOLOGY

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

The Uremic Toxin 3-Indoxyl Sulfate Is a Potent Endogenous Agonist for the Human Aryl Hydrocarbon Receptor

(2009) Jennifer C. Schroeder et al.   BIOCHEMISTRY

A Serotonin-Dependent Mechanism Explains the Leptin Regulation of Bone Mass, Appetite, and Energy Expenditure

(2009) Vijay K. Yadav et al.   CELL

Foreword

(2009) Kai-Uwe Eckardt et al.   KIDNEY INTERNATIONAL

Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms

(2009) J. C. Schefold et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The kynurenines are associated with oxidative stress, inflammation and the prevalence of cardiovascular disease in patients with end-stage renal disease

(2008) Krystyna Pawlak et al.   ATHEROSCLEROSIS

Prevalence of chronic kidney disease in population-based studies: Systematic review

(2008) Qiu-Li Zhang et al.   BMC PUBLIC HEALTH

Chronic kidney disease and hip fracture-related mortality in older people in the UK

(2008) D. Nitsch et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION