Evaluation of JNJ-54717793 a Novel Brain Penetrant Selective Orexin 1 Receptor Antagonist in Two Rat Models of Panic Attack Provocation
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Evaluation of JNJ-54717793 a Novel Brain Penetrant Selective Orexin 1 Receptor Antagonist in Two Rat Models of Panic Attack Provocation
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-06-09
DOI
10.3389/fphar.2017.00357
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Evaluation of Low versus High Volume per Minute Displacement CO2 Methods of Euthanasia in the Induction and Duration of Panic-Associated Behavior and Physiology
- (2016) Debra Hickman et al. Animals
- Orexin 2 Receptor Antagonism is Sufficient to Promote NREM and REM Sleep from Mouse to Man
- (2016) Anthony L. Gotter et al. Scientific Reports
- Recent trends in orexin research—2010 to 2015
- (2015) Christoph Boss et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Both Ox1R and Ox2R orexin receptors contribute to the cardiorespiratory response evoked from the perifornical hypothalamus
- (2015) Mirza I Beig et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- OREXIN 1 AND 2 RECEPTOR INVOLVEMENT IN CO2-INDUCED PANIC-ASSOCIATED BEHAVIOR AND AUTONOMIC RESPONSES
- (2015) Philip L. Johnson et al. DEPRESSION AND ANXIETY
- Both Ox1r and Ox2r orexin receptors contribute to the cardiovascular and locomotor components of the novelty stress response in the rat
- (2015) Mirza I. Beig et al. NEUROPHARMACOLOGY
- Orexins and fear: implications for the treatment of anxiety disorders
- (2015) África Flores et al. TRENDS IN NEUROSCIENCES
- Antagonistic interplay between hypocretin and leptin in the lateral hypothalamus regulates stress responses
- (2015) Patricia Bonnavion et al. Nature Communications
- The Hypocretin/Orexin System Mediates the Extinction of Fear Memories
- (2014) África Flores et al. NEUROPSYCHOPHARMACOLOGY
- Orexin-1 receptor blockade dysregulates REM sleep in the presence of orexin-2 receptor antagonism
- (2014) Christine Dugovic et al. Frontiers in Neuroscience
- Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls
- (2014) Jiann Wei Yeoh et al. Frontiers in Neuroscience
- Discovery and Characterization of ACT-335827, an Orally Available, Brain Penetrant Orexin Receptor Type 1 Selective Antagonist
- (2013) Michel A. Steiner et al. ChemMedChem
- Differential Effect of Orexin-1 and CRF-1 Antagonism on Stress Circuits: a fMRI Study in the Rat with the Pharmacological Stressor Yohimbine
- (2013) Alessandro Gozzi et al. NEUROPSYCHOPHARMACOLOGY
- Optogenetic examination identifies a context-specific role for orexins/hypocretins in anxiety-related behavior
- (2013) W. Heydendael et al. PHYSIOLOGY & BEHAVIOR
- Orexin/hypocretin system modulates amygdala-dependent threat learning through the locus coeruleus
- (2013) R. M. Sears et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A role for the extended amygdala in the fear-enhancing effects of acute selective serotonin reuptake inhibitor treatment
- (2013) S Ravinder et al. Translational Psychiatry
- Group II metabotropic glutamate receptor type 2 allosteric potentiators prevent sodium lactate-induced panic-like response in panic-vulnerable rats
- (2012) Philip L Johnson et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Activation of the Orexin 1 Receptor is a Critical Component of CO2-Mediated Anxiety and Hypertension but not Bradycardia
- (2012) Philip L Johnson et al. NEUROPSYCHOPHARMACOLOGY
- Orexin 1 receptors are a novel target to modulate panic responses and the panic brain network
- (2012) Philip L. Johnson et al. PHYSIOLOGY & BEHAVIOR
- An animal model of panic vulnerability with chronic disinhibition of the dorsomedial/perifornical hypothalamus
- (2012) Philip L. Johnson et al. PHYSIOLOGY & BEHAVIOR
- The brain orexin system and almorexant in fear-conditioned startle reactions in the rat
- (2012) Michel A. Steiner et al. PSYCHOPHARMACOLOGY
- The Dual Orexin Receptor Antagonist Almorexant Induces Sleep and Decreases Orexin-Induced Locomotion by Blocking Orexin 2 Receptors
- (2012) Géraldine M. Mang et al. SLEEP
- Mapping of microstimulation evoked responses and unit activity patterns in the lateral hypothalamic area recorded in awake humans
- (2011) W. Bryan Wilent et al. JOURNAL OF NEUROSURGERY
- A selective, non-peptide CRF receptor 1 antagonist prevents sodium lactate-induced acute panic-like responses
- (2010) Anantha Shekhar et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Induction of c-Fos in ‘panic/defence’-related brain circuits following brief hypercarbic gas exposure
- (2010) Philip L Johnson et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX2 receptor
- (2009) P Malherbe et al. BRITISH JOURNAL OF PHARMACOLOGY
- Hypocretin /orexin contributes to the expression of some but not all forms of stress and arousal
- (2009) Teri M. Furlong et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Induction of panic attack by stimulation of the ventromedial hypothalamus
- (2009) W. Bryan Wilent et al. JOURNAL OF NEUROSURGERY
- Blockade of Orexin-1 Receptors Attenuates Orexin-2 Receptor Antagonism-Induced Sleep Promotion in the Rat
- (2009) C. Dugovic et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A key role for orexin in panic anxiety
- (2009) Philip L Johnson et al. NATURE MEDICINE
- The orexin receptor 1 (OX1R) in the rostral medullary raphe contributes to the hypercapnic chemoreflex in wakefulness, during the active period of the diurnal cycle
- (2009) Mirela Barros Dias et al. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
- Emotional and state-dependent modification of cardiorespiratory function: Role of orexinergic neurons
- (2008) Tomoyuki Kuwaki et al. AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
- Current use of benzodiazepines in anxiety disorders
- (2008) Jean-Marc Cloos et al. CURRENT OPINION IN PSYCHIATRY
- World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Pharmacological Treatment of Anxiety, Obsessive-Compulsive and Post-Traumatic Stress Disorders – First Revision
- (2008) Borwin Bandelow et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now