The Hypocretin/Orexin System Mediates the Extinction of Fear Memories

Blocking of corticotrophin releasing factor receptor-1 during footshock attenuates context fear but not the upregulation of prepro-orexin mRNA in rats

(2014) Xiaoyu Chen et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The Hypocretin/Orexin Receptor-1 as a Novel Target to Modulate Cannabinoid Reward

(2013) África Flores et al.   BIOLOGICAL PSYCHIATRY

The hypocretins/orexins: integrators of multiple physiological functions

(2013) Jingcheng Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

Orexin Receptor-1 in the Locus Coeruleus Plays an Important Role in Cue-Dependent Fear Memory Consolidation

(2013) S. Soya et al.   JOURNAL OF NEUROSCIENCE

The contextual brain: implications for fear conditioning, extinction and psychopathology

(2013) Stephen Maren et al.   NATURE REVIEWS NEUROSCIENCE

Orexin/hypocretin system modulates amygdala-dependent threat learning through the locus coeruleus

(2013) R. M. Sears et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anxiolytic function of the orexin 2/hypocretin A receptor in the basolateral amygdala

(2013) David H. Arendt et al.   PSYCHONEUROENDOCRINOLOGY

Orexin Receptor Antagonists Differ from Standard Sleep Drugs by Promoting Sleep at Doses That Do Not Disrupt Cognition

(2013) J. M. Uslaner et al.   Science Translational Medicine

Contrasting Effects of Pretraining, Posttraining, and Pretesting Infusions of Corticotropin-Releasing Factor into the Lateral Amygdala: Attenuation of Fear Memory Formation but Facilitation of its Expression

(2012) Koichi Isogawa et al.   BIOLOGICAL PSYCHIATRY

Dynorphins Regulate Fear Memory: from Mice to Men

(2012) A. Bilkei-Gorzo et al.   JOURNAL OF NEUROSCIENCE

Post-training unilateral amygdala lesions selectively impair contextual fear memories

(2012) C. R. Flavell et al.   LEARNING & MEMORY

Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity

(2012) O Gunduz-Cinar et al.   MOLECULAR PSYCHIATRY

Genetic Strain Differences in Learned Fear Inhibition Associated with Variation in Neuroendocrine, Autonomic and Amygdala Dendritic Phenotypes

(2012) Marguerite C Camp et al.   NEUROPSYCHOPHARMACOLOGY

The brain orexin system and almorexant in fear-conditioned startle reactions in the rat

(2012) Michel A. Steiner et al.   PSYCHOPHARMACOLOGY

Individual differences in recovery from traumatic fear

(2012) Andrew Holmes et al.   TRENDS IN NEUROSCIENCES

Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress

(2011) Mohammed R. Milad et al.   Annual Review of Psychology

Hcrtr1 and 2 signaling differentially regulates depression-like behaviors

(2011) Michael M. Scott et al.   BEHAVIOURAL BRAIN RESEARCH

Hypocretin/Orexin Signaling in the Hypothalamic Paraventricular Nucleus is Essential for the Expression of Nicotine Withdrawal

(2011) Ainhoa Plaza-Zabala et al.   BIOLOGICAL PSYCHIATRY

Fear conditioning and extinction: emotional states encoded by distinct signaling pathways

(2011) Natalie C. Tronson et al.   TRENDS IN NEUROSCIENCES

Neuronal circuits of fear extinction

(2010) Cyril Herry et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Rescue of Impaired Fear Extinction and Normalization of Cortico-Amygdala Circuit Dysfunction in a Genetic Mouse Model by Dietary Zinc Restriction

(2010) N. Whittle et al.   JOURNAL OF NEUROSCIENCE

Hypocretins Regulate the Anxiogenic-Like Effects of Nicotine and Induce Reinstatement of Nicotine-Seeking Behavior

(2010) A. Plaza-Zabala et al.   JOURNAL OF NEUROSCIENCE

Dissociable Roles of Prelimbic and Infralimbic Cortices, Ventral Hippocampus and Basolateral Amygdala in the Expression and Extinction of Conditioned Fear

(2010) Demetrio Sierra-Mercado et al.   NEUROPSYCHOPHARMACOLOGY

Orexins in the paraventricular nucleus of the thalamus mediate anxiety-like responses in rats

(2010) Yonghui Li et al.   PSYCHOPHARMACOLOGY

Intact learning and memory in rats following treatment with the dual orexin receptor antagonist almorexant

(2010) Hendrik Dietrich et al.   PSYCHOPHARMACOLOGY

Abnormal activity in reward brain circuits in human narcolepsy with cataplexy

(2009) Aurélie Ponz et al.   ANNALS OF NEUROLOGY

Neurobiological Basis of Failure to Recall Extinction Memory in Posttraumatic Stress Disorder

(2009) Mohammed R. Milad et al.   BIOLOGICAL PSYCHIATRY

A key role for orexin in panic anxiety

(2009) Philip L Johnson et al.   NATURE MEDICINE

Projections of the paraventricular and paratenial nuclei of the dorsal midline thalamus in the rat

(2008) Robert P. Vertes et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Impaired Fear Extinction Learning and Cortico-Amygdala Circuit Abnormalities in a Common Genetic Mouse Strain

(2008) K. Hefner et al.   JOURNAL OF NEUROSCIENCE

Switching on and off fear by distinct neuronal circuits

(2008) Cyril Herry et al.   NATURE

Insular hypocretin transmission regulates nicotine reward

(2008) J. A. Hollander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA