The brain orexin system and almorexant in fear-conditioned startle reactions in the rat

Activation of the Orexin 1 Receptor is a Critical Component of CO2-Mediated Anxiety and Hypertension but not Bradycardia

(2012) Philip L Johnson et al.   NEUROPSYCHOPHARMACOLOGY

Favoured genetic background for testing anxiolytics in the fear-potentiated and light-enhanced startle paradigms in the rat

(2011) Michel A. Steiner et al.   BEHAVIOURAL BRAIN RESEARCH

Hcrtr1 and 2 signaling differentially regulates depression-like behaviors

(2011) Michael M. Scott et al.   BEHAVIOURAL BRAIN RESEARCH

Discovery process and pharmacological characterization of a novel dual orexin 1 and orexin 2 receptor antagonist useful for treatment of sleep disorders

(2011) Romano Di Fabio et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Orexinergic innervation of the extended amygdala and basal ganglia in the rat

(2011) Oliver Schmitt et al.   Brain Structure & Function

Orexin A in rat rostral ventrolateral medulla is pressor, sympatho-excitatory, increases barosensitivity and attenuates the somato-sympathetic reflex

(2011) Israt Z Shahid et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of orexin neurons in dorsomedial/perifornical hypothalamus and antidepressant reversal in a rodent model of depression

(2011) Mathieu Nollet et al.   NEUROPHARMACOLOGY

Evidence for a role of inhibition of orexinergic neurons in the anxiolytic and sedative effects of diazepam: A c-Fos study

(2011) Anne E. Panhelainen et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Amygdalar orexinergic–GABAergic interactions regulate anxiety behaviors of the Syrian golden hamster

(2010) Ennio Avolio et al.   BEHAVIOURAL BRAIN RESEARCH

Association between Major Mood Disorders and the hypocretin receptor 1 gene

(2010) Innocenzo Rainero et al.   JOURNAL OF AFFECTIVE DISORDERS

Differential Effects of the Dual Orexin Receptor Antagonist Almorexant and the GABAA-α1 Receptor Modulator Zolpidem, Alone or Combined with Ethanol, on Motor Performance in the Rat

(2010) Michel A Steiner et al.   NEUROPSYCHOPHARMACOLOGY

Oxytocin Reduces Background Anxiety in a Fear-Potentiated Startle Paradigm

(2010) Galen Missig et al.   NEUROPSYCHOPHARMACOLOGY

Orexins in the paraventricular nucleus of the thalamus mediate anxiety-like responses in rats

(2010) Yonghui Li et al.   PSYCHOPHARMACOLOGY

Intact learning and memory in rats following treatment with the dual orexin receptor antagonist almorexant

(2010) Hendrik Dietrich et al.   PSYCHOPHARMACOLOGY

State-dependent central chemoreception: A role of orexin

(2010) Tomoyuki Kuwaki et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Abnormal activity in reward brain circuits in human narcolepsy with cataplexy

(2009) Aurélie Ponz et al.   ANNALS OF NEUROLOGY

Orexin neurons in the hypothalamus mediate cardiorespiratory responses induced by disinhibition of the amygdala and bed nucleus of the stria terminalis

(2009) Wei Zhang et al.   BRAIN RESEARCH

Amygdaloid axons innervate melanin-concentrating hormone- and orexin-containing neurons in the mouse lateral hypothalamus

(2009) Sawako Nakamura et al.   BRAIN RESEARCH

Antidepressant-induced jitteriness/anxiety syndrome: systematic review

(2009) Lindsey I. Sinclair et al.   BRITISH JOURNAL OF PSYCHIATRY

Hypocretin /orexin contributes to the expression of some but not all forms of stress and arousal

(2009) Teri M. Furlong et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A key role for orexin in panic anxiety

(2009) Philip L Johnson et al.   NATURE MEDICINE

Effects of Substance P in the Amygdala, Ventromedial Hypothalamus and Periaqueductal Gray on Fear-Potentiated Startle

(2008) Zuowei Zhao et al.   NEUROPSYCHOPHARMACOLOGY