Translational Identification of Transcriptional Signatures of Major Depression and Antidepressant Response

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium

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Mutation of Kinesin-6 Kif20b causes defects in cortical neuron polarization and morphogenesis

(2017) Katrina C. McNeely et al.   Neural Development

Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression

(2017) Giannina Descalzi et al.   Science Signaling

Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression

(2017) Giannina Descalzi et al.   Science Signaling

Delineation of molecular pathway activities of the chronic antidepressant treatment response suggests important roles for glutamatergic and ubiquitin–proteasome systems

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Systematic review of blood transcriptome profiling in neuropsychiatric disorders: guidelines for biomarker discovery

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Understanding the epigenetic basis of sex differences in depression

(2016) Georgia E. Hodes et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis

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Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility

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Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach

(2016) Gaël Qesseveur et al.   NEUROPHARMACOLOGY

Molecular biomarkers of depression

(2016) Anand Gururajan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Blood Transcriptomic Markers in Patients with Late-Onset Major Depressive Disorder

(2016) Shigeo Miyata et al.   PLoS One

Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior

(2016) Ashley E. Lepack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Consistently altered expression of gene sets in postmortem brains of individuals with major psychiatric disorders

(2016) M M Darby et al.   Translational Psychiatry

Nature and nurture: environmental influences on a genetic rat model of depression

(2016) N S Mehta-Raghavan et al.   Translational Psychiatry

Is there Progress? An Overview of Selecting Biomarker Candidates for Major Depressive Disorder

(2016) Juan Joseph Young et al.   Frontiers in Psychiatry

Enhanced cardiac TBC1D10C expression lowers heart rate and enhances exercise capacity and survival

(2016) Cornelia Volland et al.   Scientific Reports

Identifying Predictors, Moderators, and Mediators of Antidepressant Response in Major Depressive Disorder: Neuroimaging Approaches

(2015) Mary L. Phillips et al.   AMERICAN JOURNAL OF PSYCHIATRY

Blood transcriptomic markers for major depression: from animal models to clinical settings

(2015) Eva E. Redei et al.   Annals of the New York Academy of Sciences

Biomarker approaches in major depressive disorder evaluated in the context of current hypotheses

(2015) Mike C Jentsch et al.   Biomarkers in Medicine

Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts

(2015) Fee Bengsch et al.   CELL CYCLE

Sialylation regulates brain structure and function

(2015) Seung-Wan Yoo et al.   FASEB JOURNAL

ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior

(2015) HaoSheng Sun et al.   NATURE MEDICINE

Determining the role of microRNAs in psychiatric disorders

(2015) Orna Issler et al.   NATURE REVIEWS NEUROSCIENCE

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

(2015) Janine Arloth et al.   NEURON

Fibroblasts from patients with major depressive disorder show distinct transcriptional response to metabolic stressors

(2015) K A Garbett et al.   Translational Psychiatry

Identification of genes and gene pathways associated with major depressive disorder by integrative brain analysis of rat and human prefrontal cortex transcriptomes

(2015) K Malki et al.   Translational Psychiatry

Identification of Differential MicroRNAs in Cerebrospinal Fluid and Serum of Patients with Major Depressive Disorder

(2015) Yunqiang Wan et al.   PLoS One

Are there meaningful biomarkers of treatment response for depression?

(2014) Barbara Breitenstein et al.   DRUG DISCOVERY TODAY

Towards a classification of biomarkers of neuropsychiatric disease: from encompass to compass

(2014) J Davis et al.   MOLECULAR PSYCHIATRY

MicroRNA 135 Is Essential for Chronic Stress Resiliency, Antidepressant Efficacy, and Intact Serotonergic Activity

(2014) Orna Issler et al.   NEURON

Testing the Predictive Value of Peripheral Gene Expression for Nonremission Following Citalopram Treatment for Major Depression

(2014) Jean-Philippe Guilloux et al.   NEUROPSYCHOPHARMACOLOGY

Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes

(2014) Nikolaos P. Daskalakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A review of fMRI studies during visual emotive processing in major depressive disorder

(2014) Natalia Jaworska et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy

(2014) E E Redei et al.   Translational Psychiatry

Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness

(2014) R Kohen et al.   Translational Psychiatry

Xenopus laevis nucleotide binding protein 1 (xNubp1) is important for convergent extension movements and controls ciliogenesis via regulation of the actin cytoskeleton

(2013) Andriani Ioannou et al.   DEVELOPMENTAL BIOLOGY

Calcineurin Interacts with the Serotonin Transporter C-Terminus to Modulate Its Plasma Membrane Expression and Serotonin Uptake

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Re-cycling Paradigms: Cell Cycle Regulation in Adult Hippocampal Neurogenesis and Implications for Depression

(2013) Patrícia Patrício et al.   MOLECULAR NEUROBIOLOGY

Neural correlates of dysfunctional emotion regulation in major depressive disorder. A systematic review of neuroimaging studies

(2013) Maria M. Rive et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Mitochondrial dysfunction, oxidative stress, and major depressive disorder

(2013) Edward Tobe   Neuropsychiatric Disease and Treatment

A breach in the scaffold: The possible role of cytoskeleton dysfunction in the pathogenesis of major depression

(2012) Ginger Tsz-Hin Wong et al.   AGEING RESEARCH REVIEWS

Adenylate Cyclase 7 Is Implicated in the Biology of Depression and Modulation of Affective Neural Circuitry

(2012) Jennifer Joeyen-Waldorf et al.   BIOLOGICAL PSYCHIATRY

The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance and therapeutic implications

(2012) S Moylan et al.   MOLECULAR PSYCHIATRY

Epigenetics of the Depressed Brain: Role of Histone Acetylation and Methylation

(2012) HaoSheng Sun et al.   NEUROPSYCHOPHARMACOLOGY

Nubp1 Is Required for Lung Branching Morphogenesis and Distal Progenitor Cell Survival in Mice

(2012) Carsten Schnatwinkel et al.   PLoS One

Sensitive periods in epigenetics: bringing us closer to complex behavioral phenotypes

(2012) Corina Nagy et al.   Epigenomics

Discovery of blood transcriptomic markers for depression in animal models and pilot validation in subjects with early-onset major depression

(2012) K Pajer et al.   Translational Psychiatry

Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode

(2012) R Belzeaux et al.   Translational Psychiatry

Phenome-transcriptome correlation unravels anxiety and depression related pathways

(2011) Philipp Gormanns et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: Implications for brain energy metabolism and neurotrophic signaling

(2011) W.T. Regenold et al.   JOURNAL OF PSYCHIATRIC RESEARCH

MicroRNAs in body fluids—the mix of hormones and biomarkers

(2011) Maria Angelica Cortez et al.   Nature Reviews Clinical Oncology

Chronic social defeat stress disrupts regulation of lipid synthesis

(2010) Jen-Chieh Chuang et al.   JOURNAL OF LIPID RESEARCH

Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models

(2010) B M Andrus et al.   MOLECULAR PSYCHIATRY

Rank–rank hypergeometric overlap: identification of statistically significant overlap between gene-expression signatures

(2010) Seema B. Plaisier et al.   NUCLEIC ACIDS RESEARCH

Biomarkers to Predict Antidepressant Response

(2010) Andrew F. Leuchter et al.   Current Psychiatry Reports

A Molecular Signature of Depression in the Amygdala

(2009) Etienne Sibille et al.   AMERICAN JOURNAL OF PSYCHIATRY

Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery

(2009) Mariàngels de Planell-Saguer et al.   HUMAN MOLECULAR GENETICS

Duloxetine in acute major depression: review of comparisons to placebo and standard antidepressants using dissimilar methods

(2009) Paolo Girardi et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Drug-Dependent Requirement of Hippocampal Neurogenesis in a Model of Depression and of Antidepressant Reversal

(2008) Alexandre Surget et al.   BIOLOGICAL PSYCHIATRY

Outcomes in major depressive disorder: The evolving concept of remission and its implications for treatment

(2008) Hans-Jürgen Möller   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY