Determining the role of microRNAs in psychiatric disorders

Copy Number Variable MicroRNAs in Schizophrenia and Their Neurodevelopmental Gene Targets

(2015) William Warnica et al.   BIOLOGICAL PSYCHIATRY

Early life epigenetic programming and transmission of stress-induced traits in mammals

(2014) Katharina Gapp et al.   BIOESSAYS

Genetic Studies of Major Depressive Disorder: Why Are There No Genome-wide Association Study Findings and What Can We Do About It?

(2014) Douglas F. Levinson et al.   BIOLOGICAL PSYCHIATRY

Heterogeneity and Individuality: microRNAs in Mental Disorders

(2014) Leif G. Hommers et al.   JOURNAL OF NEURAL TRANSMISSION

Long-Term Impact of Early Life Events on Physiology and Behaviour

(2014) G. J. Boersma et al.   JOURNAL OF NEUROENDOCRINOLOGY

MicroRNA-19b Associates with Ago2 in the Amygdala Following Chronic Stress and Regulates the Adrenergic Receptor Beta 1

(2014) N. Volk et al.   JOURNAL OF NEUROSCIENCE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment

(2014) Juan Pablo Lopez et al.   NATURE MEDICINE

Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice

(2014) Katharina Gapp et al.   NATURE NEUROSCIENCE

Identification and consequences of miRNA–target interactions — beyond repression of gene expression

(2014) Jean Hausser et al.   NATURE REVIEWS GENETICS

The emergence of proteome-wide technologies: systematic analysis of proteins comes of age

(2014) Michal Breker et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Amygdala-Dependent Fear Memory Consolidation via miR-34a and Notch Signaling

(2014) Brian George Dias et al.   NEURON

MicroRNA 135 Is Essential for Chronic Stress Resiliency, Antidepressant Efficacy, and Intact Serotonergic Activity

(2014) Orna Issler et al.   NEURON

The Impact of MIR137 on Dorsolateral Prefrontal–Hippocampal Functional Connectivity in Healthy Subjects

(2014) Bing Liu et al.   NEUROPSYCHOPHARMACOLOGY

Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cells

(2014) Matthew J. Hill et al.   SCHIZOPHRENIA RESEARCH

Mapping the Epigenetic Basis of Complex Traits

(2014) S. Cortijo et al.   SCIENCE

A direct molecular link between the autism candidate gene RORa and the schizophrenia candidate MIR137

(2014) Paolo Devanna et al.   Scientific Reports

Transcriptional targets of the schizophrenia risk gene MIR137

(2014) A L Collins et al.   Translational Psychiatry

Mining the 3′UTR of Autism-implicated Genes for SNPs Perturbing MicroRNA Regulation

(2014) Varadharajan Vaishnavi et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

Derepression of a Neuronal Inhibitor due to miRNA Dysregulation in a Schizophrenia-Related Microdeletion

(2013) Bin Xu et al.   CELL

MicroRNAs: regulators of neuronal fate

(2013) Alfred X Sun et al.   CURRENT OPINION IN CELL BIOLOGY

Polymorphisms in microRNA target sites influence susceptibility to schizophrenia by altering the binding of miRNAs to their targets

(2013) Yunguo Gong et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Paternal Stress Exposure Alters Sperm MicroRNA Content and Reprograms Offspring HPA Stress Axis Regulation

(2013) A. B. Rodgers et al.   JOURNAL OF NEUROSCIENCE

MicroRNA-182 Regulates Amygdala-Dependent Memory Formation

(2013) E. M. Griggs et al.   JOURNAL OF NEUROSCIENCE

Reduced Adult Hippocampal Neurogenesis and Working Memory Deficits in the Dgcr8-Deficient Mouse Model of 22q11.2 Deletion-Associated Schizophrenia Can Be Rescued by IGF2

(2013) Y. Ouchi et al.   JOURNAL OF NEUROSCIENCE

Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex

(2013) Ilaria Guella et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Identification of differentially expressed microRNAs across the developing human brain

(2013) M N Ziats et al.   MOLECULAR PSYCHIATRY

The genome-wide supported microRNA-137 variant predicts phenotypic heterogeneity within schizophrenia

(2013) T A Lett et al.   MOLECULAR PSYCHIATRY

TALEN-mediated editing of the mouse Y chromosome

(2013) Haoyi Wang et al.   NATURE BIOTECHNOLOGY

Circulating microRNAs as novel biomarkers for diabetes mellitus

(2013) Claudiane Guay et al.   Nature Reviews Endocrinology

Adult-specific functions of animal microRNAs

(2013) Kailiang Sun et al.   NATURE REVIEWS GENETICS

Effects of MIR137 on fronto-amygdala functional connectivity

(2013) Omar Mothersill et al.   NEUROIMAGE

Insights on the Functional Impact of MicroRNAs Present in Autism-Associated Copy Number Variants

(2013) Varadarajan Vaishnavi et al.   PLoS One

MIR137 gene and target gene CACNA1C of miR-137 contribute to schizophrenia susceptibility in Han Chinese

(2013) Fanglin Guan et al.   SCHIZOPHRENIA RESEARCH

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

MicroRNAs as biomarkers for CNS disease

(2013) Pooja Rao et al.   Frontiers in Molecular Neuroscience

Potential Impact of miR-137 and Its Targets in Schizophrenia

(2013) Carrie Wright et al.   Frontiers in Genetics

Age-Dependent MicroRNA Control of Synaptic Plasticity in 22q11 Deletion Syndrome and Schizophrenia

(2012) L. R. Earls et al.   JOURNAL OF NEUROSCIENCE

Non-coding RNAs with essential roles in neurodegenerative disorders

(2012) Evgenia Salta et al.   LANCET NEUROLOGY

MicroRNAs in learning, memory, and neurological diseases

(2012) W. Wang et al.   LEARNING & MEMORY

Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia

(2012) M J Green et al.   MOLECULAR PSYCHIATRY

MicroRNA profiling: approaches and considerations

(2012) Colin C. Pritchard et al.   NATURE REVIEWS GENETICS

Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain

(2012) Miao He et al.   NEURON

Impact of a microRNA MIR137 Susceptibility Variant on Brain Function in People at High Genetic Risk of Schizophrenia or Bipolar Disorder

(2012) Heather C Whalley et al.   NEUROPSYCHOPHARMACOLOGY

Mood congruent psychotic symptoms and specific cognitive deficits in carriers of the novel schizophrenia risk variant at MIR-137

(2012) E. Cummings et al.   NEUROSCIENCE LETTERS

Cell-to-cell miRNA transfer: From body homeostasis to therapy

(2012) Roxana S. Redis et al.   PHARMACOLOGY & THERAPEUTICS

Experimental validation of candidate schizophrenia gene ZNF804A as target for hsa-miR-137

(2012) Albert H. Kim et al.   SCHIZOPHRENIA RESEARCH

Horizontal transfer of microRNAs: molecular mechanisms and clinical applications

(2012) Xi Chen et al.   Protein & Cell

Deletion of Astroglial Dicer Causes Non-Cell-Autonomous Neuronal Dysfunction and Degeneration

(2011) J. Tao et al.   JOURNAL OF NEUROSCIENCE

microRNA as Repressors of Stress-Induced Anxiety: The Case of Amygdalar miR-34

(2011) S. Haramati et al.   JOURNAL OF NEUROSCIENCE

Early Prenatal Stress Epigenetically Programs Dysmasculinization in Second-Generation Offspring via the Paternal Lineage

(2011) C. P. Morgan et al.   JOURNAL OF NEUROSCIENCE

Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression

(2011) R M O'Connor et al.   MOLECULAR PSYCHIATRY

Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets

(2011) E Kwon et al.   MOLECULAR PSYCHIATRY

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory

(2011) Quan Lin et al.   NATURE NEUROSCIENCE

MicroRNAs in body fluids—the mix of hormones and biomarkers

(2011) Maria Angelica Cortez et al.   Nature Reviews Clinical Oncology

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex

(2011) Claude M Schofield et al.   Neural Development

MicroRNAs and depression

(2011) Sophie Mouillet-Richard et al.   NEUROBIOLOGY OF DISEASE

Regulation of MiR-124, Let-7d and MiR-181a in the Accumbens Affects the Expression, Extinction and Reinstatement of Cocaine-Induced Conditioned Place Preference

(2011) Vijay Chandrasekar et al.   NEUROPSYCHOPHARMACOLOGY

Experimental strategies for microRNA target identification

(2011) D. W. Thomson et al.   NUCLEIC ACIDS RESEARCH

Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex

(2011) K. Fenelon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TAL Effectors: Customizable Proteins for DNA Targeting

(2011) A. J. Bogdanove et al.   SCIENCE

Early Life Programming and Neurodevelopmental Disorders

(2010) Tracy L. Bale et al.   BIOLOGICAL PSYCHIATRY

Upregulation of Dicer and MicroRNA Expression in the Dorsolateral Prefrontal Cortex Brodmann Area 46 in Schizophrenia

(2010) Danielle M. Santarelli et al.   BIOLOGICAL PSYCHIATRY

Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys

(2010) Ronald C. Kessler et al.   BRITISH JOURNAL OF PSYCHIATRY

MicroRNA pathways in neural development and plasticity

(2010) Ngan K Vo et al.   CURRENT OPINION IN NEUROBIOLOGY

Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

(2010) Sébastien S. Hébert et al.   HUMAN MOLECULAR GENETICS

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross talk between microRNA and epigenetic regulation in adult neurogenesis

(2010) Keith E. Szulwach et al.   JOURNAL OF CELL BIOLOGY

MicroRNA Loss Enhances Learning and Memory in Mice

(2010) W. Konopka et al.   JOURNAL OF NEUROSCIENCE

Striatal microRNA controls cocaine intake through CREB signalling

(2010) Jonathan A. Hollander et al.   NATURE

A novel pathway regulates memory and plasticity via SIRT1 and miR-134

(2010) Jun Gao et al.   NATURE

Targeted integration in rat and mouse embryos with zinc-finger nucleases

(2010) Xiaoxia Cui et al.   NATURE BIOTECHNOLOGY

MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212

(2010) Heh-In Im et al.   NATURE NEUROSCIENCE

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

MicroRNA assassins: factors that regulate the disappearance of miRNAs

(2010) Zoya S Kai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Export of microRNAs and microRNA-protective protein by mammalian cells

(2010) Kai Wang et al.   NUCLEIC ACIDS RESEARCH

Genome-wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndrome

(2010) H. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiR-16 Targets the Serotonin Transporter: A New Facet for Adaptive Responses to Antidepressants

(2010) A. Baudry et al.   SCIENCE

MicroRNA miR-137 Regulates Neuronal Maturation by Targeting Ubiquitin Ligase Mind Bomb-1

(2010) Richard D. Smrt et al.   STEM CELLS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

microRNAs miR-124, let-7d and miR-181a regulate Cocaine-induced Plasticity

(2009) Vijay Chandrasekar et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Schizophrenia is associated with an increase in cortical microRNA biogenesis

(2009) N J Beveridge et al.   MOLECULAR PSYCHIATRY

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Understanding microRNAs in neurodegeneration

(2009) Stephen M. Eacker et al.   NATURE REVIEWS NEUROSCIENCE

Effects of stress throughout the lifespan on the brain, behaviour and cognition

(2009) Sonia J. Lupien et al.   NATURE REVIEWS NEUROSCIENCE

microRNAs at the synapse

(2009) Gerhard Schratt   NATURE REVIEWS NEUROSCIENCE

MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction

(2009) J. Kocerha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNAs in neurodegeneration

(2008) Natascha Bushati et al.   CURRENT OPINION IN NEUROBIOLOGY

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus

(2008) T. H. Davis et al.   JOURNAL OF NEUROSCIENCE

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

(2008) Kimberly L Stark et al.   NATURE GENETICS