Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis

The exercise-glucocorticoid paradox: How exercise is beneficial to cognition, mood, and the brain while increasing glucocorticoid levels

(2017) Chong Chen et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Pioglitazone attenuates lipopolysaccharide-induced depression-like behaviors, modulates NF-κB/IL-6/STAT3, CREB/BDNF pathways and central serotonergic neurotransmission in mice

(2017) L. Liao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment

(2016) Silvia Alboni et al.   BRAIN BEHAVIOR AND IMMUNITY

Intracerebroventricular administration of TNF-like weak inducer of apoptosis induces depression-like behavior and cognitive dysfunction in non-autoimmune mice

(2016) Jing Wen et al.   BRAIN BEHAVIOR AND IMMUNITY

Depression mediates impaired glucose tolerance and cognitive dysfunction: A neuromodulatory role of rosiglitazone

(2016) Sita Sharan Patel et al.   HORMONES AND BEHAVIOR

Icariin attenuates cerebral ischemia–reperfusion injury through inhibition of inflammatory response mediated by NF-κB, PPARα and PPARγ in rats

(2016) Deqing Xiong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Antidepressant effects of curcumin and HU-211 coencapsulated solid lipid nanoparticles against corticosterone-induced cellular and animal models of major depression

(2016) Xiaolie He et al.   International Journal of Nanomedicine

Clearing Amyloid-β through PPARγ/ApoE Activation by Genistein is a Treatment of Experimental Alzheimer’s Disease

(2016) Vicent Bonet-Costa et al.   JOURNAL OF ALZHEIMERS DISEASE

Involvement of PI3K/Akt/FoxO3a and PKA/CREB Signaling Pathways in the Protective Effect of Fluoxetine Against Corticosterone-Induced Cytotoxicity in PC12 Cells

(2016) Bingqing Zeng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Pioglitazone ameliorates the phenotype of a novel Parkinson’s disease mouse model by reducing neuroinflammation

(2016) Milena Pinto et al.   Molecular Neurodegeneration

Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition

(2016) M-L Wong et al.   MOLECULAR PSYCHIATRY

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

(2016) Ronald S Duman et al.   NATURE MEDICINE

Fluoxetine protects against IL-1β-induced neuronal apoptosis via downregulation of p53

(2016) Han Shan et al.   NEUROPHARMACOLOGY

Involvement of Infralimbic Prefrontal Cortex but not Lateral Habenula in Dopamine Attenuation After Chronic Mild Stress

(2016) Jared L Moreines et al.   NEUROPSYCHOPHARMACOLOGY

Antidepressant therapies inhibit inflammation and microglial M1-polarization

(2016) Hans O. Kalkman et al.   PHARMACOLOGY & THERAPEUTICS

PPAR-γ Agonists for the Treatment of Major Depression: A Review

(2016) R. Colle et al.   PHARMACOPSYCHIATRY

For whom the endocannabinoid tolls: Modulation of innate immune function and implications for psychiatric disorders

(2016) Rebecca J. Henry et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Impaired GABA synthesis, uptake and release are associated with depression-like behaviors induced by chronic mild stress

(2016) K Ma et al.   Translational Psychiatry

Alzheimer Disease: Crosstalk between the Canonical Wnt/Beta-Catenin Pathway and PPARs Alpha and Gamma

(2016) Alexandre Vallée et al.   Frontiers in Neuroscience

The retina as an early biomarker of neurodegeneration in a rotenone-induced model of Parkinson’s disease: evidence for a neuroprotective effect of rosiglitazone in the eye and brain

(2016) Eduardo Maria Normando et al.   Acta Neuropathologica Communications

Rosiglitazone-activated PPARγ induces neurotrophic factor-α1 transcription contributing to neuroprotection

(2015) Erwan Thouennon et al.   JOURNAL OF NEUROCHEMISTRY

Neuroinflammation and neuronal autophagic death were suppressed via Rosiglitazone treatment: New evidence on neuroprotection in a rat model of global cerebral ischemia

(2015) Zi-Qiang Shao et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Hippocampal neuroplasticity in major depressive disorder

(2015) N.V. Malykhin et al.   NEUROSCIENCE

Activation of RXR/PPARγ underlies neuroprotection by bexarotene in ischemic stroke

(2015) Michelangelo Certo et al.   PHARMACOLOGICAL RESEARCH

Molecular network of neuronal autophagy in the pathophysiology and treatment of depression

(2015) Jack Jia et al.   Neuroscience Bulletin

Depression, anxiety disorders, and metabolic syndrome in a population at risk for type 2 diabetes mellitus

(2015) Kai G. Kahl et al.   Brain and Behavior

Cobalamin status and its relation with depression, cognition and neuropathy in patients with type 2 diabetes mellitus using metformin

(2014) Elke Biemans et al.   ACTA DIABETOLOGICA

Autophagy and Its Normal and Pathogenic States in the Brain

(2014) Ai Yamamoto et al.   Annual Review of Neuroscience

Lack of seipin in neurons results in anxiety- and depression-like behaviors via down regulation of PPARγ

(2014) Libin Zhou et al.   HUMAN MOLECULAR GENETICS

Impaired autophagy: a link between neurodegenerative and neuropsychiatric diseases

(2014) Mira Polajnar et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The role of mTOR in depression and antidepressant responses

(2014) Helena M. Abelaira et al.   LIFE SCIENCES

Neurotrophic factor-α1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone

(2014) Y Cheng et al.   MOLECULAR PSYCHIATRY

Hippocampal HDAC4 Contributes to Postnatal Fluoxetine-Evoked Depression-Like Behavior

(2014) Ambalika Sarkar et al.   NEUROPSYCHOPHARMACOLOGY

Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans

(2014) Nils C. Gassen et al.   PLOS MEDICINE

Prolonged Restraint Stress Increases IL-6, Reduces IL-10, and Causes Persistent Depressive-Like Behavior That Is Reversed by Recombinant IL-10

(2013) Jeffrey L. Voorhees et al.   PLoS One

Hormones and the Social Brain

(2013) B. S. McEwen   SCIENCE

Adolescent Stress-Induced Epigenetic Control of Dopaminergic Neurons via Glucocorticoids

(2013) M. Niwa et al.   SCIENCE

Chronic Stress Triggers Social Aversion via Glucocorticoid Receptor in Dopaminoceptive Neurons

(2013) J. Barik et al.   SCIENCE

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

(2011) Jason S. Snyder et al.   NATURE

Rosiglitazone Add-On in Treatment of Depressed Patients with Insulin Resistance: a Pilot Study

(2011) Natalie L. Rasgon et al.   TheScientificWorldJOURNAL

Autophagy augmented by troglitazone is independent of EGFR transactivation and correlated with AMP-activated protein kinase signaling

(2010) Jinguo Yan et al.   Autophagy

Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis

(2010) A. Nouwen et al.   DIABETOLOGIA

Vital exhaustion, depressive symptoms and serum triglyceride levels in high-risk middle-aged men

(2010) Cornel Victor Igna et al.   PSYCHIATRY RESEARCH

Examining a Bidirectional Association Between Depressive Symptoms and Diabetes

(2008) Sherita Hill Golden   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The molecular neurobiology of depression

(2008) Vaishnav Krishnan et al.   NATURE