Regulation of Microglia and Macrophage Polarization via Apoptosis Signal-Regulating Kinase 1 Silencing after Ischemic/Hypoxic Injury

Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization

(2017) Eleni Vergadi et al.   JOURNAL OF IMMUNOLOGY

Ubiquitylation of MFHAS1 by the ubiquitin ligase praja2 promotes M1 macrophage polarization by activating JNK and p38 pathways

(2017) Jing Zhong et al.   Cell Death & Disease

Lipopolysaccharide Preconditioning Induces an Anti-inflammatory Phenotype in BV2 Microglia

(2016) Yongwei Qin et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Knockdown of apoptosis signal-regulating kinase 1 affects ischaemia-induced astrocyte activation and glial scar formation

(2016) So Yeong Cheon et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype

(2016) Ioanna Plastira et al.   Journal of Neuroinflammation

Epigenetic Control of Macrophage Polarisation and Soluble Mediator Gene Expression during Inflammation

(2016) Theodore S. Kapellos et al.   MEDIATORS OF INFLAMMATION

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

Inflammation and Stroke: An Overview

(2016) Josef Anrather et al.   Neurotherapeutics

Blockade of Apoptosis Signal-Regulating Kinase 1 Attenuates Matrix Metalloproteinase 9 Activity in Brain Endothelial Cells and the Subsequent Apoptosis in Neurons after Ischemic Injury

(2016) So Y. Cheon et al.   Frontiers in Cellular Neuroscience

Apoptosis signal-regulating kinase 1 mediates striatal degeneration via the regulation of C1q

(2016) Kyoung Joo Cho et al.   Scientific Reports

The effect of ASK1 on vascular permeability and edema formation in cerebral ischemia

(2015) Juhyun Song et al.   BRAIN RESEARCH

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Macrophage polarization in pathology

(2015) Antonio Sica et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Atorvastatin promotes human monocyte differentiation toward alternative M2 macrophages through p38 mitogen-activated protein kinase-dependent peroxisome proliferator-activated receptor γ activation

(2015) Ou Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Role of Activated Microglia and Resident Macrophages in the Neurovascular Unit during Cerebral Ischemia: Is the Jury Still Out?

(2015) Rawan Barakat et al.   MEDICAL PRINCIPLES AND PRACTICE

Immune interventions in stroke

(2015) Ying Fu et al.   Nature Reviews Neurology

In vivo analysis of neuroinflammation in the late chronic phase after experimental stroke

(2015) H.L. Walter et al.   NEUROSCIENCE

ASK1 modulates the expression of microRNA Let7A in microglia under high glucose in vitro condition

(2015) Juhyun Song et al.   Frontiers in Cellular Neuroscience

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Immunological consequences of ischemic stroke

(2013) A. Vogelgesang et al.   ACTA NEUROLOGICA SCANDINAVICA

Transcriptional Control of Macrophage Polarization

(2013) Derin Tugal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of ASK1-p38 pathway prevents neural cell death following optic nerve injury

(2012) T Katome et al.   CELL DEATH AND DIFFERENTIATION

Comparison of polarization properties of human adult microglia and blood-derived macrophages

(2012) Bryce A. Durafourt et al.   GLIA

Cerebroprotective effects of red ginseng extract pretreatment against ischemia-induced oxidative stress and apoptosis

(2012) So Yeong Cheon et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Class A scavenger receptor attenuates myocardial infarction-induced cardiomyocyte necrosis through suppressing M1 macrophage subset polarization

(2011) Yulong Hu et al.   BASIC RESEARCH IN CARDIOLOGY

Apoptosis signal-regulating kinase 1 (Ask1) targeted small interfering RNA on ischemic neuronal cell death

(2011) Hyun-Woo Kim et al.   BRAIN RESEARCH

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway

(2010) Xiaoli Guo et al.   EMBO Molecular Medicine

Critical role for apoptosis signal-regulating kinase 1 in the development of inflammatory K/BxN serum-induced arthritis

(2010) Stephen J. Mnich et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Myeloid-Specific Deletion of the Mineralocorticoid Receptor Reduces Infarct Volume and Alters Inflammation During Cerebral Ischemia

(2010) Ryan A. Frieler et al.   STROKE

Inflammation and brain injury: Acute cerebral ischaemia, peripheral and central inflammation

(2009) A. Denes et al.   BRAIN BEHAVIOR AND IMMUNITY

Inflammatory and Neuroimmunomodulatory Changes in Acute Cerebral Ischemia

(2009) David Brea et al.   CEREBROVASCULAR DISEASES

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

The blood–brain barrier and immune function and dysfunction

(2009) William A. Banks et al.   NEUROBIOLOGY OF DISEASE

Post-ischemic brain damage: pathophysiology and role of inflammatory mediators

(2008) Diana Amantea et al.   FEBS Journal

Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice

(2008) Bettina H Clausen et al.   Journal of Neuroinflammation

Immune-To-Brain Signaling: How Important are the Blood–Brain Barrier-independent Pathways?

(2008) Ning Quan   MOLECULAR NEUROBIOLOGY

Apoptosis Signal-Regulating Kinase 1 in Stress and Immune Response

(2007) Kohsuke Takeda et al.   Annual Review of Pharmacology and Toxicology

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark