Haploinsufficiency of NADPH Oxidase Subunit Neutrophil Cytosolic Factor 2 Is Sufficient to Accelerate Full-Blown Lupus in NZM 2328 Mice

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1 /G-CSF axis

(2015) J. Bagaitkar et al.   BLOOD

Phagocyte NADPH oxidase and specific immunity

(2015) Julien Cachat et al.   CLINICAL SCIENCE

The role of neutrophils in the pathogenesis of systemic lupus erythematosus

(2015) Carolyne K. Smith et al.   CURRENT OPINION IN RHEUMATOLOGY

Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation

(2015) Rikard Holmdahl et al.   IMMUNOLOGICAL REVIEWS

Systemic Lupus Erythematosus-associated Neutrophil Cytosolic Factor 2 Mutation Affects the Structure of NADPH Oxidase Complex

(2015) Don L. Armstrong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive Oxygen Species Deficiency Induces Autoimmunity with Type 1 Interferon Signature

(2014) Tiina Kelkka et al.   ANTIOXIDANTS & REDOX SIGNALING

Inflammatory manifestations in a single-center cohort of patients with chronic granulomatous disease

(2014) Alessandra Magnani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Development of Systemic Lupus Erythematosus in NZM 2328 Mice in the Absence of any Single BAFF Receptor

(2013) Chaim O. Jacob et al.   ARTHRITIS AND RHEUMATISM

NETosis: how vital is it?

(2013) B. G. Yipp et al.   BLOOD

Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations

(2013) Xana Kim-Howard et al.   HUMAN MOLECULAR GENETICS

Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus

(2013) Jason S. Knight et al.   JOURNAL OF CLINICAL INVESTIGATION

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

Endocytosis of soluble immune complexes leads to their clearance by Fc RIIIB but induces neutrophil extracellular traps via Fc RIIA in vivo

(2012) K. Chen et al.   BLOOD

Type I IFN system in the development and manifestations of SLE

(2012) Keith B. Elkon et al.   CURRENT OPINION IN RHEUMATOLOGY

NADPH Oxidase Inhibits the Pathogenesis of Systemic Lupus Erythematosus

(2012) A. M. Campbell et al.   Science Translational Medicine

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase

(2011) C. O. Jacob et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

p47phoxPhox Homology Domain Regulates Plasma Membrane but Not Phagosome Neutrophil NADPH Oxidase Activation

(2010) Xing Jun Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40phox and selective defects in neutrophil NADPH oxidase activity

(2009) J. D. Matute et al.   BLOOD

Accelerated Pathological and Clinical Nephritis in Systemic Lupus Erythematosus-Prone New Zealand Mixed 2328 Mice Doubly Deficient in TNF Receptor 1 and TNF Receptor 2 via a Th17-Associated Pathway

(2009) N. Jacob et al.   JOURNAL OF IMMUNOLOGY

Macrophage NADPH Oxidase Flavocytochrome b Localizes to the Plasma Membrane and Rab11-Positive Recycling Endosomes

(2009) A.-J. Casbon et al.   JOURNAL OF IMMUNOLOGY

Chronic Granulomatous Disease: The European Experience

(2009) J. Merlijn van den Berg et al.   PLoS One

Vav1: A hematopoietic signal transduction molecule involved in human malignancies

(2008) Shulamit Katzav   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase

(2008) Michela G. Schäppi et al.   Seminars in Immunopathology