Phagocyte NADPH oxidase and specific immunity

TCR-triggered extracellular superoxide production is not required for T-cell activation

(2014) Aleksey V Belikov et al.   Cell Communication and Signaling

NADPH Oxidase Modifies Patterns of MHC Class II-Restricted Epitopic Repertoires through Redox Control of Antigen Processing

(2014) E. R. O. Allan et al.   JOURNAL OF IMMUNOLOGY

Tryptophan catabolism is unaffected in chronic granulomatous disease

(2014) Ghassan J. Maghzal et al.   NATURE

How should eosinophilic cystitis be treated in patients with chronic granulomatous disease?

(2014) Alessia Claps et al.   PEDIATRIC NEPHROLOGY

Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice

(2014) I. Khmaladze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deficiency of gp91phoxInhibits Allergic Airway Inflammation

(2013) Carla M. Sevin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD

(2013) M. Y. Zeng et al.   BLOOD

B-cell activating factor (BAFF) is elevated in Chronic Granulomatous Disease

(2013) Kabir Matharu et al.   CLINICAL IMMUNOLOGY

Molecular Identification of Bacterial DNA in the Chorioretinal Scars of Chronic Granulomatous Disease

(2013) Yujuan Wang et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Which NADPH Oxidase Isoform Is Relevant for Ischemic Stroke? The Case for Nox 2

(2012) Timo Kahles et al.   ANTIOXIDANTS & REDOX SIGNALING

Humans with chronic granulomatous disease maintain humoral immunologic memory despite low frequencies of circulating memory B cells

(2012) S. Moir et al.   BLOOD

Prolonged Production of Reactive Oxygen Species in Response to B Cell Receptor Stimulation Promotes B Cell Activation and Proliferation

(2012) Matthew L. Wheeler et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: NADPH Oxidase Modulates MHC Class II Antigen Presentation by B Cells

(2012) V. L. Crotzer et al.   JOURNAL OF IMMUNOLOGY

Hyperinflammation of chronic granulomatous disease is abolished by NOX2 reconstitution in macrophages and dendritic cells

(2012) Christine Deffert et al.   JOURNAL OF PATHOLOGY

Immunoglobulin resistance in Kawasaki disease with chronic granulomatous disease

(2012) Mitsuru Tsuge et al.   PEDIATRICS INTERNATIONAL

Extensive Natural Variation for Cellular Hydrogen Peroxide Release Is Genetically Controlled

(2012) Homa Attar et al.   PLoS One

NADPH Oxidase Inhibits the Pathogenesis of Systemic Lupus Erythematosus

(2012) A. M. Campbell et al.   Science Translational Medicine

Role of p47phox in Antigen-Presenting Cell-Mediated Regulation of Humoral Immunity in Mice

(2011) Sam Vasilevsky et al.   AMERICAN JOURNAL OF PATHOLOGY

Superoxide Dismutase 3 Suppresses Hyaluronic Acid Fragments Mediated Skin Inflammation by Inhibition of Toll-Like Receptor 4 Signaling Pathway: Superoxide Dismutase 3 Inhibits Reactive Oxygen Species-Induced Trafficking of Toll-Like Receptor 4 to Lipid Rafts

(2011) Myung-Ja Kwon et al.   ANTIOXIDANTS & REDOX SIGNALING

Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms

(2011) D. R. Balce et al.   BLOOD

Expansion of T helper type 17 lymphocytes in patients with chronic granulomatous disease

(2011) R. Horváth et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH-independent manner

(2011) Joanna M Rybicka et al.   EMBO JOURNAL

Ligation of CD40 receptor in human B lymphocytes triggers the 5-lipoxygenase pathway to produce reactive oxygen species and activate p38 MAPK

(2011) Yun Jung Ha et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

TNF-α blockade in chronic granulomatous disease–induced hyperinflammation: Patient analysis and murine model

(2011) Christine Deffert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inheritance Pattern and Clinical Aspects of 93 Iranian Patients with Chronic Granulomatous Disease

(2011) Fatemeh Fattahi et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Low Interleukin-17A Production in Response to Fungal Pathogens in Patients with Chronic Granulomatous Disease

(2011) Sanne P. Smeekens et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Ncf1 (p47phox) Is Essential for Direct Regulatory T Cell Mediated Suppression of CD4+ Effector T Cells

(2011) Olga Efimova et al.   PLoS One

NADPH Oxidase-2 Derived ROS Dictates Murine DC Cytokine-Mediated Cell Fate Decisions during CD4 T Helper-Cell Commitment

(2011) Meghan A. Jendrysik et al.   PLoS One

Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells

(2011) K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redox Remodeling Allows and Controls B-Cell Activation and Differentiation

(2010) Roberta Vené et al.   ANTIOXIDANTS & REDOX SIGNALING

Tryptophan/kynurenine metabolism in human leukocytes is independent of superoxide and is fully maintained in chronic granulomatous disease

(2010) S. S. De Ravin et al.   BLOOD

Mitochondrial Reactive Oxygen Species Control T Cell Activation by Regulating IL-2 and IL-4 Expression: Mechanism of Ciprofloxacin-Mediated Immunosuppression

(2010) M. M. Kaminski et al.   JOURNAL OF IMMUNOLOGY

Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease

(2010) Douglas B. Kuhns et al.   NEW ENGLAND JOURNAL OF MEDICINE

Incomplete Kawasaki disease in a patient with chronic granulomatous disease

(2010) Jun Muneuchi et al.   PEDIATRICS INTERNATIONAL

Phosphoinositide 3-kinase-dependent regulation of Na+/H+ exchanger in dendritic cells

(2010) Anand Rotte et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

NADPH oxidase activity controls phagosomal proteolysis in macrophages through modulation of the lumenal redox environment of phagosomes

(2010) J. M. Rybicka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Redox Regulation of ORAI Ion Channels: A Mechanism to Tune Cellular Calcium Signaling

(2010) I. Bogeski et al.   Science Signaling

Autoantibody-dependent and autoantibody-independent roles for B cells in systemic lupus erythematosus: Past, present, and future

(2009) Noam Jacob et al.   AUTOIMMUNITY

BCR-induced superoxide negatively regulates B-cell proliferation and T-cell-independent type 2 Ab responses

(2009) Sabrina M. Richards et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nox proteins in signal transduction

(2009) David I. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE

Three common polymorphisms in theCYBAgene form a haplotype associated with decreased ROS generation

(2009) Karen Bedard et al.   HUMAN MUTATION

Role of NADPH oxidase-2 in lipopolysaccharide-induced matrix metalloproteinase expression and cell migration

(2009) So-Yeon Kim et al.   IMMUNOLOGY AND CELL BIOLOGY

Ocular manifestations in chronic granulomatous disease in Saudi Arabia

(2009) Saleh Al-Muhsen et al.   JOURNAL OF AAPOS

Ncf1-Associated Reduced Oxidative Burst Promotes IL-33R+ T Cell-Mediated Adjuvant-Free Arthritis in Mice

(2009) K. Hagenow et al.   JOURNAL OF IMMUNOLOGY

Autoimmune thyroiditis and ROS

(2008) C. Lynne Burek et al.   AUTOIMMUNITY REVIEWS

NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

(2008) A. R. Mantegazza et al.   BLOOD

Th17 development and autoimmune arthritis in the absence of reactive oxygen species

(2008) Annie George-Chandy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Chronic granulomatous disease as a risk factor for autoimmune disease

(2008) Suk See De Ravin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification of Pseudomonas aeruginosa DNA in a chorioretinal lesion associated with chronic granulomatous disease

(2008) A A Herzlich et al.   JOURNAL OF CLINICAL PATHOLOGY

Reactive oxygen species play a central role in the activity of cationic liposome based cancer vaccine

(2008) Weili Yan et al.   JOURNAL OF CONTROLLED RELEASE

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

(2008) Luigina Romani et al.   NATURE

Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase

(2008) Michela G. Schäppi et al.   Seminars in Immunopathology

The NADPH oxidase NOX2 plays a role in periodontal pathologies

(2008) Catherine Giannopoulou et al.   Seminars in Immunopathology

Clinical features, long-term follow-up and outcome of a large cohort of patients with Chronic Granulomatous Disease: An Italian multicenter study

(2007) Baldassarre Martire et al.   CLINICAL IMMUNOLOGY